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  • Saturday, Jun 24th
    18:00 – 18:30 ET
    PL 01.2 - A Life Spent Investigating Coagulation Factor V
    Room: 517
    Speaker: Björn Dahlbäck, MD, PhD (he/him/his) – Lund University
    Coagulation and Natural Anticoagulants
  • Sunday, Jun 25th
    07:00 – 07:45 ET
    MC 03.1 - COVID, Complement and Coagulation
    Room: Wilcom Room at the InterContinental Montreal
    Speaker: Edward M Conway, MD, PhD – Centre for Blood Research, University of British Columbia
    Coagulation and Natural Anticoagulants
  • Sunday, Jun 25th
    08:00 – 09:15 ET
    SOA 02.4 - Emerging Concepts in Coagulation Factor Variants
    Room: 516
    Moderator: David-Alexandre TREGOUET, PhD (he/him/his) – Bordeaux Population Health research center - INSERM UMR1219
    Moderator: Jorge Di Paola, MD (he/him/his) – Washington University School of Medicine
    Coagulation and Natural Anticoagulants
  • Sunday, Jun 25th
    08:00 – 08:25 ET
    SOA 02.1 - Complex Trait Genetics in Thrombosis and Hemostasis
    Room: 516
    Speaker: Karl C. Desch, MD (he/him/his) – University of Michigan
    Coagulation and Natural Anticoagulants
  • Sunday, Jun 25th
    08:25 – 08:50 ET
    SOA 02.2 - FV Variants in Bleeding and Thrombosis
    Room: 516
    Speaker: Elisabetta Castoldi, PhD – Department of Biochemistry, CARIM, Maastricht University, Maastricht (The Netherlands)
    Coagulation and Natural Anticoagulants
  • Sunday, Jun 25th
    08:50 – 09:15 ET
    SOA 02.3 - Genetics of the Antithrombin-Prothrombin Axis
    Room: 516
    Speaker: Javier Corral, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    07:00 – 07:45 ET
    MC 19.1 - Structure and Function of Coagulation factors
    Room: Belfour Room at the InterContinental Montreal
    Speaker: Mettine Bos, PhD – Leiden University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    08:00 – 09:15 ET
    SOA 12.4 - Targeting Coagulation by the Natural World
    Room: 516
    Moderator: Mettine Bos, PhD – Leiden University Medical Center
    Moderator: Reheman Adili, MD – Bloodworks Research Institute
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    08:00 – 08:25 ET
    SOA 12.1 - Molecular Basis of Anticoagulant Tick Salivary Proteins
    Room: 516
    Speaker: Ingrid Dijkgraaf, PhD (she/her/hers) – Maastricht University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    08:25 – 08:50 ET
    SOA 12.2 - Evolution of Proteases in Venoms From Pitvipers and Beyond
    Room: 516
    Speaker: Ana Maria Moura da Silva, PhD (she/her/hers) – Butantan Institute
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    08:50 – 09:15 ET
    SOA 12.3 - Variegin, a Potent Direct Thrombin Inhibitor From Tick Saliva
    Room: 516
    Speaker: Manjunatha R. Kini, PhD (he/him/his) – National University of Singapore
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    10:45 – 12:00 ET
    OC 31.6 - DOAC Reversal: Current Practice and Emerging Concepts
    Room: 516
    Moderator: Yesim G. Dargaud, MD, PhD – University Lyon 1
    Moderator: Lacra Ivanciu, PhD – University of Pennsylvania/Children's Hospital of Philadelphia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    10:45 – 11:00 ET
    OC 31.1 - Management and Outcomes of Anticoagulated Patients in Urgent Surgery: The PAUSE-ER Study
    Room: 516
    Presenting Author: Deborah M. Siegal, MD MSc FRCPC – The Ottawa Hospital
    Co-Author: Eleni Arnaoutoglou – General University Hospital of Larissa
    Co-Author: Mark Blostein, MDCM – Jewish General Hospital
    Co-Author: Lana A. Castellucci, MD, MSc – Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada.
    Co-Author: John Eikelboom – Hamilton Health Sciences - General Hospital
    Co-Author: Rohit Gandhi – Hopital Montfort/Institut du Savoir Montfort
    Co-Author: Peter L. Gross, MD MSc FRCP(c) (he/him/his) – Department of Medicine, McMaster University
    Co-Author: Scott Kaatz, DO, MSc – Henry Ford Health
    Co-Author: Gregoire Le Gal, MD PhD – Ottawa Hospital Research Institute, University of Ottawa, Canada
    Co-Author: Sam Schulman, MD, PhD – Department of Medicine, Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada.
    Co-Author: Vinay Shah – Henry Ford Health System
    Co-Author: Konstantinos Stamoulis – General University Hospital of Larissa
    Co-Author: Alfonso Tafur, MD, MS, MBA (he/him/his) – Northshore University HealthSystem, Cardiovascular Institute
    Co-Author: Kelly Vogt – London Health Sciences Centre, Victoria Hospital
    Co-Author: Joanne Nixon – McMaster University
    Co-Author: Melanie St John – McMaster University
    Co-Author: Meera Karunakaran – McMaster University
    Co-Author: Bambie Levoy-Jones – McMaster University
    Co-Author: James Douketis, MD (he/him/his) – McMaster University/St. Joseph's Healthcare
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    11:00 – 11:15 ET
    OC 31.2 - Andexanet Alfa Is Associated With Lower In-Hospital Mortality Compared To 4-Factor Prothrombin Complex Concentrate In Patients With Factor Xa Inhibitor–Related Major Bleeding
    Room: 516
    Presenting Author: Paul P. Dobesh, PharmD, FACC, FAHA, FACC, BCPS, BCCP – University of Nebraska Medical Center College of Pharmacy
    Co-Author: Craig I. Coleman, PharmD – University of Connecticut
    Co-Author: Mark Danese – Outcomes Insights
    Co-Author: Mary J. Christoph – AstraZeneca Pharmaceuticals
    Co-Author: Eva Lesen – AstraZeneca
    Co-Author: Hungta Chen – AstraZeneca Pharmaceuticals
    Co-Author: Julie Ulloa – Outcomes Insights
    Co-Author: Sherry Danese – Outcomes Insights
    Co-Author: Bruce Koch – AstraZeneca
    Co-Author: Gregory J. Fermann – Department of Emergency Medicine, University of Cincinnati
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    11:15 – 11:30 ET
    OC 31.3 - Phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of VMX-C001 in healthy subjects
    Room: 516
    Presenting Author: Gerard Short, MRCP FFPM MBA – VarmX, Leiden, The Netherlands
    Co-Author: Daniël Verhoef – VarmX, Leiden, The Netherlands
    Co-Author: Tainá Gomes – VarmX, Leiden, The Netherlands
    Co-Author: Henri Spronk – Coagulation Profile, Maastricht, The Netherlands
    Co-Author: Jan Ohrstrom – VarmX, Leiden, The Netherlands
    Co-Author: Bo Persson – VarmX, Leiden, The Netherlands
    Co-Author: Jeffrey I. Weitz – McMaster University and the Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada
    Co-Author: Pieter Reitsma – VarmX, Leiden, The Netherlands
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    11:30 – 11:45 ET
    OC 31.4 - Novel Factor Xa agents that restore hemostasis in mice treated with apixaban
    Room: 516
    Presenting Author: Wojciech Jankowski, PhD – US Food and Drug Administration (FDA)
    Co-Author: Nancy Hernandez – FDA
    Co-Author: Stepan S. Surov – FDA
    Co-Author: Atul Rawal – FDA
    Co-Author: Marcos Battistel – FDA
    Co-Author: Darón I. Freedberg – US Food and Drug Administration
    Co-Author: Mikhail V. Ovanesov – US Food and Drug Administration
    Co-Author: Zuben E. Sauna – U.S. Food and Drug Administration
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    11:45 – 12:00 ET
    OC 31.5 - Novel Snake Venom Hemocoagulase Reverses Anticoagulant Effect of Factor Xa Inhibitors and Restores Hemostasis in Vitro and in Vivo
    Room: 516
    Presenting Author: Reheman Adili, MD – Bloodworks Research Institute
    Co-Author: Nicole Rhoads – Bloodworks Research Institute
    Co-Author: Michael Wong – Lee's Pharmaceutical Holdings Ltd.
    Co-Author: Benjamin Li – Lee's Pharmaceutical Holdings Ltd.
    Co-Author: Junmei Chen, PhD – Bloodworks Research Institute
    Co-Author: Dominic Chung – Bloodworks Research Institute
    Co-Author: José López – Bloodworks Research Institute
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    14:45 – 16:00 ET
    OC 41.6 - Contact Pathway: Structure and Function I
    Room: 516
    Moderator: Joost C.M Meijers, PhD (he/him/his) – Department of Experimental Vascular Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands
    Moderator: Bassem M. Mohammed, BPharm, PhD (he/him/his) – Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    14:45 – 16:00 ET
    OC 45.6 - Integrating Knowledge on Coagulation
    Room: 511
    Moderator: Stephanie  A. Smith, DVM – University of Michigan
    Moderator: Yaqiu Sang, PhD – UNC at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    14:45 – 15:00 ET
    OC 41.1 - Structural Identification of the Factor XII - uPAR Binding Interface For Selective Drug Development.
    Room: 516
    Presenting Author: Dillon J. Bohinc (he/him/his) – Department of Medicine, Hematology and Oncology Division, CWRU School of Medicine, Cleveland, OH, USA.
    Co-Author: Kara L. Bane – Department of Medicine, Hematology and Oncology Division, CWRU School of Medicine, Cleveland, OH, USA.
    Co-Author: Maria de la Fuente – Department of Pharmacology, CWRU School of Medicine, Cleveland, OH, USA.
    Co-Author: Shruti Raghunathan – Department of Biomedical Engineering, Case Western Reserve University
    Co-Author: Marvin T. Nieman – Case Western Reserve University
    Co-Author: Steven de Maat, PhD – Department of CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
    Co-Author: Helen Philippou, PhD – University of Leeds.
    Co-Author: Jonas Emsley, Phd – Nottingham Biodiscovery Institute, School of Pharmacy
    Co-Author: Coen Maas, PhD – CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Thomas Renné – Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
    Co-Author: Anirban Sen Gupta, PhD (he/him/his) – Case Western Reserve University
    Co-Author: Evi X. Stavrou, MD – Department of Medicine, Hematology and Oncology Division, CWRU School of Medicine, Cleveland, OH, USA.
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    14:45 – 15:00 ET
    OC 45.1 - A genome-wide CRISPR-Cas9 knockout screen reveals FSP1 as the warfarin-resistant vitamin K reductase
    Room: 511
    Co-Author: Da-Yun Jin – University of North Carolina at Chapel Hill
    Co-Author: Xuejie Chen – University of North Carolina at Chapel Hill
    Co-Author: Yizhou Liu – University of Queensland
    Co-Author: Criag Williams – University of Queensland, Australia
    Co-Author: Lars Pedersen – NIEHS
    Co-Author: Darrel Stafford – University of North Carolina at Chapel Hill
    Presenting Author: Jian-Ke Tie, PhD – University of North Carolina at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:00 – 15:15 ET
    OC 41.2 - Coagulation factor XII-independent contribution of kallikrein to contact pathway-mediated thrombin generation in mouse whole blood
    Room: 516
    Co-Author: Jun Wan, PhD (he/him/his) – Cyrus Tang Hematology Center, Soochow University
    Co-Author: Rohan Kathuri – University of North Carolina at Chapel Hill
    Co-Author: Sophia Dhrolia – University of North Carolina at Chapel Hill
    Co-Author: Mark Roest, PhD (he/him/his) – Department of Platelet pathophysiology, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill
    Co-Author: Rafal Pawlinski, PhD – Division of Hematology and Blood Research Center, University of North Carolina at Chapel Hill
    Co-Author: Pavan K. Bendapudi – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Boston, MA
    Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill
    Presenting Author: Steven P. Grover, PhD – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:00 – 15:15 ET
    OC 45.2 - Knockdown of Zebrafish Tmem242 Enhances Production of ROS That Signals to Increase Foxa2 and Foxa3 Expression That May Increase Clotting Factors Resulting in Thrombosis and Bleeding
    Room: 511
    Presenting Author: Afnan O. Deebani, Master of Science in Biology (she/her/hers) – University of North Texas
    Co-Author: Weam Fallatah – University of North Texas
    Co-Author: Ayah Al Qaryoute – University of North Texas
    Co-Author: Pudur Jagadeeswaran, PhD – University of North Texas
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:15 – 15:30 ET
    OC 41.3 - Intramolecular interactions that stabilize factor XII in a closed form
    Room: 516
    Co-Author: ALEKSANDR SHAMANAEV, PhD – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Maxim Litvak, MD PhD – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Jonas Emsley, Phd – Nottingham Biodiscovery Institute, School of Pharmacy
    Presenting Author: David Gailani, MD – Vanderbilt University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:15 – 15:30 ET
    OC 45.3 - Major Bleeding Event Rates in Patients on Hemodialysis and Peritoneal Dialysis: Results from the International DOPPS and PDOPPS
    Room: 511
    Co-Author: Murilo Guedes – Arbor Research Collaborative for Health
    Co-Author: Junhui Zhao – Arbor Research Collaborative for Health
    Co-Author: Catelyn Coyle – Merck & Co., Inc.
    Co-Author: Lori D. Bash – Merck & Co., Inc.
    Co-Author: Dena Ramey – Merck & Co., Inc.
    Co-Author: G. Brandon Atkins – Merck and Co., Inc.
    Co-Author: David Johnson – Department of Kidney and Transplant Services, University of Queensland at Princess Alexandra Hospital
    Co-Author: Almudena Vega – Hospital Universitario Infanta Leonor: Hospital Infanta Leonor
    Co-Author: Pablo Urena – AURA Nord Saint Ouen
    Co-Author: Pietro Manuel Ferraro – Università Cattolica del Sacro Cuore
    Co-Author: Mohammed Al Ghonaim – Medicine Department, Saudi Center for Organ Transplantation, King Saud University
    Presenting Author: Marc P. Bonaca, MD MPH FAHA FACC (he/him/his) – University of Colorado School of Medicine
    Co-Author: Roberto Pecoits-Filho – Arbor Research Collaborative for Health
    Co-Author: Angelo Karaboyas – Arbor Research Collaborative for Health
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:30 – 15:45 ET
    OC 45.4 - Crucial roles of red blood cells and platelets in coagulation
    Room: 511
    Presenting Author: Siyu Sun, MS – Synapse rsearch institute
    Co-Author: Jinmi Zou – Synapse research insitute
    Co-Author: Elena Campello, MD, PhD (she/her/hers) – Department of Medicine, University of Padova, Italy
    Co-Author: Joke Konings, PhD – Synapse Research Institute
    Co-Author: Dana Huskens, PhD – Synapse research insitute
    Co-Author: Jun Wan, PhD (he/him/his) – Cyrus Tang Hematology Center, Soochow University
    Co-Author: Delia Fernandez – Maastricht university
    Co-Author: Chris Reutelingsperger – Maastricht university
    Co-Author: Hugo ten Cate, MD, PhD, FAHA (he/him/his) – Thrombosis Expertise Center, Heart & Vascular Center, Maastricht University Medical Center, Maastricht, the Netherlands
    Co-Author: Serena Toffanin – University of Padua
    Co-Author: Cristiana Bulato – Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, University of Padua Medical School, Padua (Italy)
    Co-Author: Philip G. de Groot – Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Bas de Laat, MD, PhD – Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Paolo Simioni, MD, PhD (he/him/his) – Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, University of Padua Medical School, Padua (Italy)
    Co-Author: Johan W. M. Heemskerk – Synapse research insitute
    Co-Author: Mark Roest, PhD (he/him/his) – Department of Platelet pathophysiology, Synapse Research Institute, Maastricht, the Netherlands
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:45 – 16:00 ET
    OC 41.5 - Two positively charged patches in the EGF-1 domain of Factor XII synergistically contribute to surface binding and activation
    Room: 516
    Presenting Author: Rowan Frunt, MSc – Department of CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Hinde El Otmani, MSc – Department of CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Simone Smits – Department of CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Chantal Clark – Van Creveldkliniek - Center for Benign Hematology, Thrombosis and Hemostasis, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Coen Maas, PhD – CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    15:45 – 16:00 ET
    OC 45.5 - The lethality in mice treated with intravenous polyphosphate is not due to thrombosis
    Room: 511
    Presenting Author: Rida A. Malik, HBSc – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Co-Author: Ji Zhou – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Co-Author: James C. Fredenburgh, PhD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Co-Author: Jeff S. Healey – McMaster University
    Co-Author: Jeffrey I. Weitz, MD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0516 - Andexanet alfa versus 4-F prothrombin complex concentrate in an apixaban anticoagulated porcine polytrauma model
    Room: Exhibition
    Co-Author: Oliver Grottke, MD, PhD – Department of Anaesthesiology, RWITH Aachen University Hospital, Aachen, Germany
    Co-Author: Till Braunschweig – MD
    Co-Author: Rolf Rossaint – Medical Doctor
    Presenting Author: Farahnaz Rayatdoost, MSc (she/her/hers) – MSc
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0517 - Enhancement of experimental venous thrombosis in sickle trait mice is prevented by Gardos channel inhibition.
    Room: Exhibition
    Presenting Author: Steven P. Grover, PhD – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Fatima Trebak – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Anton Ilich, MD – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Yuriy Prokopenko – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Erica M. Sparkenbaugh, PhD (she/her/hers) – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Malgorzata Kasztan – University of Alabama at Birmingham
    Co-Author: Nigel S. Key – Division of Hematology, University of North Carolina, Chapel Hill, NC, USA
    Co-Author: Rafal Pawlinski, PhD – Division of Hematology and Blood Research Center, University of North Carolina at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0518 - Novel insights into antifibrinolytic and prothrombotic functions of lipoprotein(a)
    Room: Exhibition
    Presenting Author: Justin Clark, MSc (he/him/his) – Western University
    Co-Author: Julia St. John – Western University
    Co-Author: Michael B. Boffa, PhD – Western University, Robarts Research Institute
    Co-Author: Marlys Koschinsky – Western University, Robarts Research Institute
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0519 - Age-Dependent Changes in Mortality and Biomarkers of Immunothrombosis in a Murine Model of Sepsis
    Room: Exhibition
    Presenting Author: Neha Sharma, B.Sc and MS – McMaster University - The Thrombosis & Atherosclerosis Research Institute
    Co-Author: Alex Chen – McMaster University
    Co-Author: Leah Heinen – McMaster University
    Co-Author: Ruth Liu – McMaster University
    Co-Author: Dhruva Dwivedi – McMaster University - The Thrombosis & Atherosclerosis Research Institute
    Co-Author: Patricia Liaw, PhD (she/her/hers) – McMaster University - The Thrombosis & Atherosclerosis Research Institute
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0520 - Atorvastatin treatment inhibits the procoagulant properties of a 3D culture model of the human neointimal layer
    Room: Exhibition
    Co-Author: Jassim Echrish – Ibn-Alnafees Hospital for heart diseases
    Co-Author: Madalina Pasca – Keele University
    Co-Author: Ying Yang, PhD – the 6th Medical Centre of Chinese PLA General Hospital
    Presenting Author: Alan GS Harper, MA, PhD – Keele University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0521 - Development and characterization of novel nanoparticulate carrier for oral delivery of low molecular weight heparin
    Room: Exhibition
    Presenting Author: Saurabh Bhargava – United Institute of Pharmacy
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0522 - Characterization of Coagulopathy in a Swine Muscle Injury Model
    Room: Exhibition
    Presenting Author: Chih Jen Yang, MD – Oregon Health & Science University
    Co-Author: Martin A. Schreiber – Oregon Health & Science University
    Co-Author: Michael P. Hutchens – Oregon Health & Science University
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: Cristina Puy, PhD – Oregon Health & Science University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0523 - Effect of Flow on Structural and Mechanical Properties of the Fibrin Network in Plasma Thrombi
    Room: Exhibition
    Presenting Author: Hande Eyisoylu, MSc – Department of Hematology, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Co-Author: Emmelien Hazekamp – Department of Hematology, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Co-Author: Gijsje H. Koenderink – Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands
    Co-Author: Moniek P.M. de Maat, PhD – Department of Hematology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0524 - Preparation and Characterization of Nanocarriers for Transdermal Delivery of Enoxaparin
    Room: Exhibition
    Presenting Author: Mani Bhargava, M.Ph – Signa College of Pharmacy
    Co-Author: Saurabh Bhargava – United Institute of Pharmacy
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0525 - Identification of an aberrant cell population in a knock-in murine model with RUNX1 variant generated by CRISPR/Cas9
    Room: Exhibition
    Presenting Author: Ana Marin-Quilez, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, University of Murcia, IMIB, CIBERER-U765, Murcia, Spain
    Co-Author: Ignacio García-Tuñón – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: José Luis Ordoñez – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain; Laboratory of Pharmacology, Department of Physiology and Pharmacology, Faculty of Pharmacy, University of Salamanca, Salamanca, Spain
    Co-Author: Mónica del Rey – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: David Sanz – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: Lorena Díaz-Ajenjo – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: Carmen Guerrero – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: Jesús Pérez-Losada – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: Jose Ramon Gonzalez Porras – Hospital Clínico Universitario Salamanca
    Co-Author: Jesús María Hernández-Rivas – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain; Hospital Clínico Universitario Salamanca
    Co-Author: Rocío Benito – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain
    Co-Author: José RIVERA Rivera, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Jose Mª Bastida, PhD, MD – Complejo Asistencial Universitario de Salamanca-IBSAL-USAL (Salamanca)
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0527 - Assessment of the rats model of hemophilic arthritis by Micro CT scanning
    Room: Exhibition
    Co-Author: Shuang Chen, master of medicine – North China University of Technology Affiliated Hospital
    Co-Author: Shi-Bo Zhang – Affiliated Hospital of North China University of Technology
    Co-Author: Yan-Yan Xie – Affiliated Hospital of North China University of Technology
    Co-Author: Ji-Ji Xu – Affiliated Hospital of North China University of Technology
    Co-Author: Jun Yang – Affiliated Hospital of North China University of Technology
    Co-Author: Wen-Qi Wu – Affiliated Hospital of North China University of Technology
    Co-Author: Lin-Hong Wang – Affiliated Hospital of North China University of Technology
    Co-Author: Dong-Nan Li – Affiliated Hospital of North China University of Technology
    Presenting Author: Zhen-Yu Yan – Affiliated Hospital of North China University of Technology
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0529 - Haemostatic properties of Chromolaena odorata: evaluation of in vivo and in vitro activity
    Room: Exhibition
    Presenting Author: Evidence Nwabueze Okoroiwu, Msc (he/him/his) – Arthur Jarvis University, Akpabuyo
    Co-Author: Henshaw Uchechi Okoroiwu – Arthur Jarvis University
    Co-Author: Ifeyinwa Maryann Okafor – University of Calabar
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0530 - Sex-Specific Differences in Procoagulant Profiles
    Room: Exhibition
    Co-Author: Andréa Coy-Canguçu – Catholic Pontifical University of Campinas
    Presenting Author: Fernanda A. Orsi – University of São Paulo Medical School
    Co-Author: Frits R. R. Rosendaal – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Co-Author: Suzanne C. Cannegieter, MD PhD – Department of Clinical Epidemiology, Leiden University Medical Center
    Co-Author: Luuk Scheres – Leiden University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0531 - Mechanical behavior of clots: Molecular mechanism of forced unfolding of crosslinked fibrin protofibrils
    Room: Exhibition
    Co-Author: Valeri Barsegov – University of Massachusetts Lowell
    Co-Author: Farkhad Maksudov – University of Massachusetts Lowell
    Co-Author: Alexander Nikanshin – University of Massachusetts Lowell
    Co-Author: Anna Protopopova – UPenn
    Presenting Author: Rustem I. Litvinov, MD, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: John W. Weisel, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0532 - The Factor XIa Antibody Osocimab Combined with Enoxaparin Strongly Inhibits Clotting in Extracorporeal Circuits in vitro
    Room: Exhibition
    Co-Author: Eslam Samaha – Department of Clinical Pharmacology
    Presenting Author: Katarina D. Kovacevic, PhD – Department of Clinical Pharmacology, Medical University of Vienna
    Co-Author: Michael Schwameis – Department of Clinical Pharmacology
    Co-Author: Sabine Schranz – Department of Clinical Pharmacology, Medical University of Vienna
    Co-Author: Bruno Watschinger – Department of Internal Medicine III, Division of Nephrology, Center for Medical Physics and Biomedical Engineering,
    Co-Author: Anja Buchmüller – Bayer
    Co-Author: Martin Stoiber – Medical Univeristy of Vienna
    Co-Author: Bernd Jilma – department of Clinical Pharmacology
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0533 - New low molecular weight heparin antidote based on an antithrombin mutant
    Room: Exhibition
    Presenting Author: David Zaragoza Huesca, PhD student – Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla
    Co-Author: Julia Peñas Martínez – Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla
    Co-Author: Salvador Espín – Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla
    Co-Author: Isabel Zuazu – Centro Regional de Hemodonación, Hospital Universitario Morales Meseguer, IMIB-Pascual Parrilla
    Co-Author: Horacio Cano – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain.
    Co-Author: María Luisa Lozano – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain
    Co-Author: Irene Martínez Martínez, PhD – Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0534 - Rapid Measurement of DOAC Concentration and Platelet Function Using Whole Blood in a Disposable Microfluidic Device
    Room: Exhibition
    Co-Author: Jason M. Rossi – FloBio LLC
    Co-Author: Karen Panckeri – Department of Medicine, University of Pennsylvania
    Co-Author: Soumita Ghosh – Institute for Translational Medicine and Therapeutics, University of Pennsylvania
    Co-Author: Tilo Grosser – Institute for Translational Medicine and Therapeutics, University of Pennsylvania
    Co-Author: Adam Cuker, MD, MS (he/him/his) – Department of Medicine and Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Presenting Author: Scott Diamond, PhD – Institute for Medicine and Engineering, Dept. Chemical and Biomolecular Engineering, University of Pennsylvania
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0535 - Development of function-blocking antibodies to plasma prekallikrein for the study of the interplay between coagulation and inflammation
    Room: Exhibition
    Presenting Author: Samantha A. Moellmer – Oregon Health & Science University
    Co-Author: Yong-Ping Zhong – OHSU
    Co-Author: Mao-fu Sun – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Cristina Puy, PhD – Oregon Health & Science University
    Co-Author: Philip Streeter – OHSU
    Co-Author: Joseph J. Shatzel – Oregon Health & Science University
    Co-Author: Karina Nakayama – OHSU
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: Erik I. Tucker – Aronora, Inc.
    Co-Author: Christina U. Lorentz – Aronora, Inc
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0536 - Oral Factor XIIa inhibitor KV998086 protects against FeCl3 induced thrombosis in mice.
    Room: Exhibition
    Presenting Author: Allen C. Clermont, MS – KalVista Pharmaceuticals
    Co-Author: Freya Pinckney – KalVista Pharmaceuticals, Ltd
    Co-Author: Marza Hill – KalVista Pharmaceuticals
    Co-Author: Sally Hampton – KalVista Pharmaceuticals, Ltd
    Co-Author: Edward Feener – KalVista Pharmaceuticals
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0537 - Tissue Factor Pathway Inhibitor and Tissue Factor Pathway Inhibitor-rs7586970 variant in Myocardial Infarction with Type 2 Diabetes Mellitus
    Room: Exhibition
    Presenting Author: Doha Abdelhamid – Faculty of medicine Suez canal university
    Co-Author: Noha Kamel – Faculty of medicine Suez canal university
    Co-Author: Ahmed Abdellah – Faculty of medicine Suez canal university
    Co-Author: Nevene Ramsis – Faculty of medicine Suez canal university
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0538 - A monoclonal antibody against human factor V impairs its activation and procoagulant function
    Room: Exhibition
    Presenting Author: Francis Ayombil, PhD – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
    Co-Author: Sean M. Quinn – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
    Co-Author: Emily A. Cid – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
    Co-Author: Matthew W. Bunce – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
    Co-Author: Rodney M. Camire, PhD – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0539 - Detection of TFPI citrullination in blood after neutrophil activation by PMA.
    Room: Exhibition
    Co-Author: Bryan RC Bouwens – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Co-Author: Stella Thomassen – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Co-Author: Elke Magdelyns – Department of Biochemistry, Cardiovascular research institute Maastricht, Maastricht University
    Presenting Author: Rory R. Koenen, PhD (he/him/his) – Maastricht University
    Co-Author: Tilman M. Hackeng, PhD – Coagulation Profile, Maastricht, The Netherlands
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0541 - Expression of recombinant human Factor VII activating protease (FSAP) and exploration of its 3D structure using AlphaFold.
    Room: Exhibition
    Co-Author: Sai Priya Sarma Kandanur – University of Oslo
    Co-Author: Monika Pathak – University of Nottingham
    Presenting Author: Jonas Emsley, Phd – Nottingham Biodiscovery Institute, School of Pharmacy
    Co-Author: Sandip M. M. Kanse – University of Oslo
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0542 - Investigating thrombin-loaded fibrin in whole blood clot microfluidic assay via fluorogenic peptide.
    Room: Exhibition
    Co-Author: Jennifer Crossen – University of Pennsylvania
    Presenting Author: Scott Diamond, PhD – Institute for Medicine and Engineering, Dept. Chemical and Biomolecular Engineering, University of Pennsylvania
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0543 - Like heparin, polyphosphate promotes the formation of a ternary complex with thrombin and fibrin
    Room: Exhibition
    Presenting Author: Xintong (Hester) Yao (she/her/hers) – McMaster University
    Co-Author: James C. Fredenburgh, PhD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Co-Author: Jeffrey I. Weitz, MD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0544 - Management of inherited antithrombin deficiency in pregnancy and puerperium: Single center experience
    Room: Exhibition
    Co-Author: AMAIA LOPEZ-PEÑA – MIGUEL SERVET UNIVERSITARY HOSPITAL
    Co-Author: Marta Sofia Ordas – MIGUEL SERVET UNIVERSITY HOSPITAL
    Co-Author: Carmen Rodriguez – MIGUEL SERVET UNIVERSITARY HOSPITAL
    Co-Author: Javier Corral, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain
    Co-Author: Maria Eugenia de la Morena-Barrio, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Arrixaca, CIBERER, Murcia, Spain
    Co-Author: Mar Herrero – MIGUEL SERVET UNIVERSITARY HOSPITAL
    Co-Author: Pablo Estuardo Lopez-Gomez – Miguel Servet Universitary Hospital
    Co-Author: Rita Gonzalez-Resina – Miguel Servet Universitary Hospital
    Co-Author: Jhossyuriel Obregon-membreño – Miguel Servet Universitary Hospital
    Co-Author: Laura Fernandez-Cuezva – Miguel Servet Universitary Hospital
    Co-Author: Leire Etxebarria-Bahillo – Miguel Servet Universitary Hospital
    Co-Author: Laura Villarroya-Martinez – MIGUEL SERVET UNIVERSITARY HOSPITAL
    Co-Author: Rafael monleon-Gil – MIGUEL SERVET UNIVERSITARY HOSPITAL
    Presenting Author: Jose Manuel Calvo-Villas, MD – Miguel Servet Universitary Hospital
    Co-Author: Nuria Fernández-Mosteirín, PhD MD – Hospital Universitario Miguel Servet (Zaragoza)
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0545 - The Effect of a History of Preeclampsia on Hemostatic Balance in the Non-pregnant State
    Room: Exhibition
    Presenting Author: Christine E. Horn – The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Maria Bravo, PhD – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Thomas Orfeo, PhD – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Lorinda Roberts, MA – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Kelley McLean, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Ira Bernstein, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0546 - Effect of Atorvastatin on IL-6 and F1+2 in High Risk Thrombosis Patients with Cancer Undergoing Chemotherapy
    Room: Exhibition
    Presenting Author: Budi Setiawan, MD, PhD (he/him/his) – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Widi Budianto – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Tri Wahyu Sukarnowati, MD (she/her/hers) – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Daniel Rizky – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Eko Adhi Pangarsa – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Damai Santosa – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Co-Author: Catharina Suharti – Hematology-Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Diponegoro University/Dr. Kariadi Hospital, Semarang, Indonesia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0547 - Poly(sodium styrenesulfonate)-based copolymers with anticoagulant activity: preliminary efficacy and safety studies
    Room: Exhibition
    Presenting Author: Justyna Swieton, MSc (she/her/hers) – Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland
    Co-Author: Natalia Marcinczyk – Department of Biopharmacy and Radiopharmacy, Medical University of Bialystok, Bialystok, Poland
    Co-Author: Anna Gromotowicz-Poplawska – Department of Biopharmacy and Radiopharmacy, Medical University of Bialystok, Bialystok, Poland
    Co-Author: Shin-ichi Yusa – Department of Applied Chemistry, University of Hyogo, Hyogo, Japan
    Co-Author: Krzysztof Szczubialka – Faculty of Chemistry, Jagiellonian University, Krakow, Poland
    Co-Author: Dariusz Pawlak – Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland
    Co-Author: Andrzej Mogielnicki – Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland
    Co-Author: Bartlomiej Kalaska – Department of Pharmacodynamics, Medical University of Bialystok, Bialystok, Poland
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0548 - Efficacy of direct oral anticoagulants in liver cirrhosis: an in-vitro study
    Room: Exhibition
    Presenting Author: Cindy Pereira Portela, MD Student – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Maxime Grégoire G. Zermatten – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Debora Bertaggia Calderara, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Montserrat Fraga – Division of Gastroenterology and Hepatology, Lausanne University Hospital and University of Lausanne
    Co-Author: Alessandro Aliotta, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Lucas Veuthey, BSc, MSc (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Durre Shehwar, MSc MPhil – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Darius Moradpour – Division of Gastroenterology and Hepatology, Lausanne University Hospital and University of Lausanne
    Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0549 - Healthcare Resource Use Among US Veterans Treated With Andexanet Alfa or 4-factor Prothrombin Complex Concentrate for Factor Xa Inhibitor-related Major Bleeding
    Room: Exhibition
    Co-Author: S. Scott Sutton – Dorn Research Institute, Columbia VA Healthcare System; Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina
    Co-Author: Joseph Magagnoli – Dorn Research Institute, Columbia VA Healthcare System; Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina
    Co-Author: Tammy H. Cummings – Dorn Research Institute, Columbia VA Healthcare System; Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina
    Co-Author: Mary J. Christoph – AstraZeneca Pharmaceuticals
    Co-Author: Raymond Chang – AstraZeneca Pharmaceuticals
    Co-Author: Hungta Chen – AstraZeneca Pharmaceuticals
    Co-Author: Phillip Hunt – AstraZeneca Pharmaceuticals
    Co-Author: James W. Hardin – Dorn Research Institute, Columbia VA Healthcare System; Department of Epidemiology and Biostatistics, University of South Carolina
    Presenting Author: Karolina Andersson-Sundell, MSc, PhD – AstraZeneca
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0550 - Novel Variants of PROS1 Gene Related to Protein S Deficiency
    Room: Exhibition
    Co-Author: Alaa Malik, BS (she/her/hers) – LSUHSC
    Co-Author: Manoj Kumar – LSUHSC
    Co-Author: Verima Pereira – LSUHSC
    Co-Author: Jovanny Zabaleta – LSUHSC
    Presenting Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0551 - A comparison of USP Potency Adjusted and Mass Adjusted Heparins of Bovine, Ovine, and Porcine Origin in Various Assays
    Room: Exhibition
    Presenting Author: Emily Krupa, BS – Loyola University Chicago
    Co-Author: Guy Olson, BS – Stritch School of Medicine
    Co-Author: Debra Hoppensteadt – Loyola University Chicago
    Co-Author: Walter Jeske – Loyola University
    Co-Author: Jawed Fareed, n/a – Loyola University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0552 - Performance evaluation of the ACTICHROME Heparin Anti-Xa™ assay for the quantitative determination of unfractionated heparin and low-molecular-weight heparin plasma concentrations.
    Room: Exhibition
    Co-Author: Clémentine Wahl – AP.HP Sorbonne Université
    Co-Author: Catherine Pelé – AP.HP Sorbonne Université
    Co-Author: Loane Poulet – AP.HP Sorbonne Université
    Co-Author: Elodie Lesteven – AP.HP Sorbonne Université
    Presenting Author: Corinne Frere, MD, PhD (she/her/hers) – AP.HP Sorbonne Université
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0553 - Role of International Society of Thrombosis and Hemostasis-Bleeding Assessment Tool, RICOF, ROTEM, and APTT-Clot wave form Analysis (CWA) in evaluation of patients with Bleeding of Unknown Cause (BUC)
    Room: Exhibition
    Presenting Author: Sreya Punjadath Baby, MD,PDF (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Laya Thomas – Christian Medical College and Hospital Vellore
    Co-Author: Rutvi Gautam Dave, MBBS, MD, Post-Doctoral Fellow – Christian Medical College and Hospital Vellore
    Co-Author: Tulasi Geevar, MBBS, MD (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Ramya Vijayan – Christian Medical College and Hospital
    Co-Author: Surendar singh – Christian Medical College and Hospital Vellore
    Co-Author: Sukesh Chandran Nair – Christian Medical College and Hospital Vellore
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0554 - A phase 1/2 study to determine the dose-response relationship by assessment of thrombin generation after 4-factor PCC in healthy subjects under vitamin K antagonist anticoagulation
    Room: Exhibition
    Presenting Author: Thomas C.F Bodewes, MD, PhD (he/him/his) – Prothya Biosolutions
    Co-Author: Vladislava Zamfirova – Prothya Biosolutions
    Co-Author: Salah Hadi – ICON Netherlands
    Co-Author: Maya Isaila – Prothya Biosolutions
    Co-Author: Hartwig Gajek – Hesyra-Medical GmbH
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0555 - Efficacy and safety of 4-factor prothrombin complex concentrate for management for direct Xa inhibitor-induced major bleeding
    Room: Exhibition
    Presenting Author: Paul P. Dobesh, PharmD, FACC, FAHA, FACC, BCPS, BCCP – University of Nebraska Medical Center College of Pharmacy
    Co-Author: Emilie A. Langenhan – Nebraska Medicine
    Co-Author: Heidi L. Brink – Nebraska Medicine
    Co-Author: Jordan D. Kuck – University of Nebraska Medical Center College of Pharmacy
    Co-Author: Adam L. Roskam – University of Nebraska Medical Center College of Pharmacy
    Co-Author: Madison J. Suckstorf – University of Nebraska Medical Center College of Pharmacy
    Co-Author: Cora K. Svoboda – University of Nebraska Medical Center College of Pharmacy
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0556 - Evaluation of the ACL TOP 970 CL analyser for clotting, chromogenic and immunoturbidimetric assays for thrombophilia
    Room: Exhibition
    Presenting Author: Kieron Hickey, MSC – Sheffield Haemophilia and Thrombosis Centre
    Co-Author: Thomas Pitchford – Sheffield Haemophilia and Thrombosis Centre
    Co-Author: Steve Kitchen, PhD – Sheffield Haemophilia and Thrombosis Centre
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0557 - Fermentation of Sweet Corn Produced A Very High Concentration of Vitamin K₂
    Room: Exhibition
    Presenting Author: Hiroyuki Sumi, PhD – Kurashiki University of Science and the Arts
    Co-Author: Yasuhide Yanagisawa – Chiba Institute of Science
    Co-Author: Sawa Naito – Kurashiki University of Science and the Arts
    Co-Author: Tadashi Mitsuo – Mitsuo Clinic
    Co-Author: Chieko Yatagai – Kurashiki University of Science and the Arts
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0558 - Lack of interaction of milvexian, an investigational oral FXIa inhibitor with aspirin and ticagrelor on platelet aggregation, thrombin generation and thromboelastography in vitro
    Room: Exhibition
    Co-Author: Matthew W. Bunce – Division of Hematology and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
    Co-Author: Zheng Huang Devine – Janssen Research & Development LLC
    Presenting Author: Madhu Chintala, PhD – Janssen Research & Development LLC
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0559 - Novel Variants of PROS1 Gene Related to Protein S Deficiency
    Room: Exhibition
    Presenting Author: Alaa Malik, BS (she/her/hers) – LSUHSC
    Co-Author: Manoj Kumar – LSUHSC
    Co-Author: Jovanny Zabaleta – LSUHSC
    Co-Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0560 - Step-by-step production and biological evaluation of novel aryl piperazine-based FXa inhibitors
    Room: Exhibition
    Co-Author: Francisca Durán-Osorio – Pontificia Universidad Católica de Chile
    Co-Author: Sebastián Morales-Guerrero – Pontificia Universidad Católica de Chile
    Co-Author: Diego Rodríguez – Pontificia Universidad Católica de Chile
    Presenting Author: Flavia C. Zacconi, PhD – Pontificia Universidad Católica de Chile
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0562 - Effects of high-fat and high-carbohydrate meals on coagulation and anticoagulation factors and lipid profile
    Room: Exhibition
    Presenting Author: Hiroko Tsuda, MD, PhD (she/her/hers) – Nakamura Gakuen University
    Co-Author: Kenta Noguchi – Nakamura Gakuen University
    Co-Author: Mana M. Kawae – Nakamura Gakuen University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0563 - Evaluation of the rapid and easy-to-use point-of-care qLabs FIB® system to quantify functional fibrinogen levels in patients undergoing plasma exchange therapy
    Room: Exhibition
    Co-Author: Samir Saheb – AP.HP Sorbonne Université
    Co-Author: Murielle Maison – AP.HP Sorbonne Université
    Co-Author: Clémentine Wahl – AP.HP Sorbonne Université
    Co-Author: Morgane Bockenmeyer – Stago Biocare
    Co-Author: Cécile Cornillot – Stago Biocare
    Co-Author: Michel Arock – AP.HP Sorbonne Université
    Presenting Author: Corinne Frere, MD, PhD (she/her/hers) – AP.HP Sorbonne Université
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0564 - Evaluation of the significance of mixing study in lupus anticoagulant testing using a new CMC algorithm
    Room: Exhibition
    Presenting Author: Sreya Punjadath Baby, MD,PDF (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Rutvi Gautam Dave, MBBS, MD, Post-Doctoral Fellow – Christian Medical College and Hospital Vellore
    Co-Author: Tulasi Geevar, MBBS, MD (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Surendar singh – Christian Medical College and Hospital Vellore
    Co-Author: Ramya Vijayan – Christian Medical College and Hospital
    Co-Author: Sukesh Chandran Nair – Christian Medical College and Hospital Vellore
    Co-Author: Jansi Rani – Christian Medical College & Hospital
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0565 - Long-term ex-situ normothermic machine perfusion of human livers provides a platform to study (patho)physiology and production of hemostatic proteins
    Room: Exhibition
    Presenting Author: Bianca Lascaris, MD (she/her/hers) – UMCG
    Co-Author: Silke B. Bodewes – UMCG
    Co-Author: Jelle Adelmeijer – UMCG
    Co-Author: Maarten W.N. Nijsten – UMCG
    Co-Author: Robert J. Porte – Erasmus MC
    Co-Author: Vincent E. Meijer – UMCG
    Co-Author: Ton Lisman, PhD – UMCG
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0566 - Prediction and validation of the effects of targeting either coagulation FXI activation or activity on thrombin generation
    Room: Exhibition
    Presenting Author: Si Han Wang, PhD (she/her/hers) – Oregon Health & Science University
    Co-Author: Hari Lakshmanan, MS, PhD – Oregon Health & Science University
    Co-Author: Meghan E. Fallon – Oregon Health & Science University
    Co-Author: Helen H. Vu – Oregon Health & Science University
    Co-Author: Joseph J. Shatzel – Oregon Health & Science University
    Co-Author: Cristina Puy, PhD – Oregon Health & Science University
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Co-Author: Erik I. Tucker – Aronora, Inc.
    Co-Author: Christina U. Lorentz – Aronora, Inc
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0568 - X-Ray Structures of Thrombin Bound to Heterobifunctional Aptamer-Drug Conjugates Reveal the Mechanistic Basis for a Novel Tethered Inhibition Strategy
    Room: Exhibition
    Presenting Author: Shekhar Kumar – The Children's Hospital of Philadelphia, Philadelphia, United States
    Co-Author: Haixiang Yu – Duke University, Durham, United States
    Co-Author: Bruce A. Sullenger – Duke University, Durham, United States
    Co-Author: Sriram Krishnaswamy, PhD – The Children’s Hospital of Philadelphia, Philadelphia, United States
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0569 - Elevated International Normalized Ratio in Hospitalized Patients Treated with Direct Oral Anticoagulants
    Room: Exhibition
    Presenting Author: Orly Efros, MD, MHA (she/her/hers) – National Hemophilia Center and Thrombosis & Hemostasis Institute, Sheba Medical Center, Israel. Sackler Faculty of Medicine, Tel Aviv University, Israel.
    Co-Author: Gili Kenet, MD – The National Hemophilia Center, and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Tel Aviv University, Tel Aviv, Israel
    Co-Author: Aharon Lubetsky – National Hemophilia Center and Thrombosis & Hemostasis Institute, Sheba Medical Center, Israel. Sackler Faculty of Medicine, Tel Aviv University, Israel.
    Co-Author: Eyal Klang – Arc Innovation Center, Sheba Medical Center, Israel. Sackler Faculty of Medicine, Tel Aviv University, Israel.
    Co-Author: shelly soffer – Internal Medicine B, Assuta Medical Center, Israel. Ben-Gurion University of the Negev, Israel
    Co-Author: Noam Barda – ARC Innovation Center, Sheba Medical Center, Ramat-Gan, Israel. Software and Information Systems Engineering, Ben Gurion University, Be’er Sheva, Israel. 6 Epidemiology, Biostatistics and Community Health Services, Ben-Gurion University of the Negev, Be’er Sheva, Israel.
    Co-Author: Avshalom Leibowitz – Department of Internal Medicine “D” and Hypertension unit, Sheba Medical Center, Israel. Sackler Faculty of Medicine, Tel Aviv University, Israel.
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0570 - A comparison of Heparins from Porcine and Bovine Origins in Various Laboratory Assays
    Room: Exhibition
    Presenting Author: Emily Krupa, BS – Loyola University Chicago
    Co-Author: Debra Hoppensteadt – Loyola University Chicago
    Co-Author: Walter Jeske – Loyola University
    Co-Author: Jawed Fareed, n/a – Loyola University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0571 - Analysis of the risk factors on the development of thromboembolic complications
    Room: Exhibition
    Co-Author: Lucia Stančiaková, MD, PhD. (she/her/hers) – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Katarína Chromeková – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Kristína Vajdová, MD, PhD. – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Miroslava Dobrotová – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Pavol Holly – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Ingrid Skornova, Ing. – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Jela Ivanková – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Jana Zolkova, DSc, PhD (she/her/hers) – National Centre of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Slovakia
    Co-Author: Ľubica Vadelová – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia 2Center of Hemostasis and Thrombosis - Unilabs Slovakia, s. r. o., Martin, Slovakia
    Co-Author: Peter Kubisz – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Presenting Author: Jan Stasko, MD, PhD (he/him/his) – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0572 - Potency-adjusted bovine heparin exhibits similar anticoagulant effects as porcine heparin in whole blood clotting studies
    Room: Exhibition
    Co-Author: Andrew J. Alcazar – Loyola University Medical Center
    Co-Author: Omer Iqbal – Loyola University Medical Center
    Co-Author: Guy Olson, BS – Stritch School of Medicine
    Co-Author: Walter Jeske – Loyola University
    Presenting Author: Emily Krupa, BS – Loyola University Chicago
    Co-Author: Dilany Aliaga, RN – Loyola University Chicago
    Co-Author: Jawed Fareed, n/a – Loyola University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0573 - Routine haemostasis profile in sickle cell disease patients in steady state: a retrospective, descriptive study
    Room: Exhibition
    Co-Author: Comlan Louis AFFO, MD – Assistance-Publique–Hôpitaux de Paris (AP-HP), Université Paris Cité
    Co-Author: Carine SCHMIDT – Assistance-Publique–Hôpitaux de Paris (AP-HP), Université Paris Cité
    Co-Author: Antoine BOSQUET – Assistance-Publique–Hôpitaux de Paris (AP-HP), Université Paris Cité
    Co-Author: Benedicte DUMONT – Assistance-Publique–Hôpitaux de Paris (AP-HP), Université Paris Cité
    Presenting Author: Isabelle MAHE, MD, PhD (she/her/hers) – Paris Cité University, APHP, Hôpital Louis Mourier, Colombes, Internal Medicine Department, INSERM UMR_S1140, and F-CRIN InnoVTE, France
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0574 - Severe Bleeding in an Acquired Factor XIII Deficiency in an Otherwise Healthy Patient
    Room: Exhibition
    Co-Author: Bianca Santonastaso – Department of Pathology and Laboratory Medicine, Transfusion Medicine Unit, University of Rochester Medical Center, Rochester, New York, USA
    Co-Author: Hannah Spector – Department of Pathology and Laboratory Medicine, Transfusion Medicine Unit, University of Rochester Medical Center, Rochester, New York, USA
    Co-Author: Christine Cahill – Department of Pathology and Laboratory Medicine, Transfusion Medicine Unit, University of Rochester Medical Center, Rochester, New York, USA
    Co-Author: Frank Akwaa – Internal Medicine Department, Hematology Unit, University of Rochester Medical Center, Rochester, New York, USA
    Co-Author: Jainulabdeen J. Ifthikharuddin – Internal Medicine Department, Hematology Unit, University of Rochester Medical Center, Rochester, New York, USA
    Co-Author: Gahyun Gim – Internal Medicine Department, Hematology Unit, University of Rochester Medical Center, Rochester, New York, USA
    Presenting Author: Majed A. Refaai, MD – Department of Pathology and Laboratory Medicine, Transfusion Medicine Division, Hemostasis and Thrombosis Unit, University of Rochester Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0575 - Novel Variants of PROS1 Gene Related to Protein S Deficiency
    Room: Exhibition
    Presenting Author: Alaa Malik, BS (she/her/hers) – LSUHSC
    Co-Author: Diana Polania-Villanueva – LSUHSC
    Co-Author: Manoj Kumar – University of Alabama at Birmingham
    Co-Author: Jone Garai – LSUHSC
    Co-Author: Jovanny Zabaleta – LSUHSC
    Co-Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0576 - Correlation between high affinity material for antithrombin and anticoagulant activities of heparin
    Room: Exhibition
    Presenting Author: John Hogwood, BSc, PhD (he/him/his) – SR&I, MHRA, UK
    Co-Author: Elaine Gray – King's College London
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0577 - Heparin Potency Assays – reagents can cause differences in potency assignment
    Room: Exhibition
    Presenting Author: John Hogwood, BSc, PhD (he/him/his) – SR&I, MHRA, UK
    Co-Author: Shreya Malik – SR&I, MHRA, UK
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0578 - Antithrombin deficiency responsible for repeated thromboembolic complications – case report
    Room: Exhibition
    Co-Author: Lucia Stančiaková, MD, PhD. (she/her/hers) – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Pavol Holly – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Kristína Vajdová, MD, PhD. – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Ivan Sámel – Department of Orthopedics, University Hospital in Martin, Martin, Slovakia
    Co-Author: Ingrid Skornova, Ing. – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Jela Ivanková – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Co-Author: Jana Zolkova, DSc, PhD (she/her/hers) – National Centre of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Slovakia
    Co-Author: Ľubica Vadelová – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia 2Center of Hemostasis and Thrombosis - Unilabs Slovakia, s. r. o., Martin, Slovakia
    Co-Author: Tomáš Bolek – Department of Internal Medicine I, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, University Hospital in Martin, Martin, Slovakia
    Co-Author: Matej Samoš – Department of Internal Medicine I, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, University Hospital in Martin, Martin, Slovakia
    Co-Author: Peter Kubisz – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Presenting Author: Jan Stasko, MD, PhD (he/him/his) – National Center of Hemostasis and Thrombosis, Department of Hematology and Transfusion Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Martin, Slovakia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0579 - Approaches to assure similarity of pharmaceutical preparations of unfractionated heparin
    Room: Exhibition
    Presenting Author: Francisco Felipe Bezerra, PhD – Federal University of Rio de Janeiro
    Co-Author: Stephan Oliveira – Federal University of Rio de Janeiro
    Co-Author: Adriana Piquet – Federal University of Rio de Janeiro
    Co-Author: Eduardo Vilanova – Federal University of Rio de Janeiro
    Co-Author: Ana Tovar – Federal University of Rio de Janeiro
    Co-Author: Rodrigo Sales – Federal University of Rio de Janeiro
    Co-Author: Nina Capille – Federal University of Rio de Janeiro
    Co-Author: Paulo A. S. Mourão – UFRJ
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0580 - Laboratory diagnosis of Prekallikrein deficiency: importance of suspicion and laboratory method
    Room: Exhibition
    Co-Author: Teresa Sevivas – Department of Blood and Transfusion Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Elsa Gonçalves – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Celeste Freire – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Telma Marques – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Teresa Ferreira – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Ana Lúcia Correia – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Guiomar Rasteiro – Department of Laboratory Medicine, Coimbra Hospital and Universitary Centre, Portugal
    Co-Author: Jose Mª Bastida, PhD, MD – Complejo Asistencial Universitario de Salamanca-IBSAL-USAL (Salamanca)
    Presenting Author: João Mariano Pego, Medical Doctor – Department of Clinical Pathology, Coimbra Hospital and Universitary Centre, Portugal
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0582 - Differential neutralization of bovine heparins as measured by functional assays and absolute quantification of glycosaminoglycan context
    Room: Exhibition
    Co-Author: Charulatha Papineni – Loyola University Medical Center
    Presenting Author: Emily Krupa, BS – Loyola University Chicago
    Co-Author: Omer Iqbal – Loyola University Medical Center
    Co-Author: Andrew J. Alcazar – Loyola University Medical Center
    Co-Author: Debra Hoppensteadt – Loyola University Chicago
    Co-Author: Walter Jeske – Loyola University
    Co-Author: Jawed Fareed, n/a – Loyola University Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0584 - Using heparin-calibrated assays to assess anti-factor Xa activity of factor Xa inhibitors (FXaI): a literature correlation analysis
    Room: Exhibition
    Presenting Author: Ravindra Sarode, MD – University of Texas Southwestern Medical Center
    Co-Author: Paul Bassett – Portland Medical Communications Ltd.
    Co-Author: James Glossop – Portland Medical Communications Ltd.
    Co-Author: Stephan Maack – Octapharma AG
    Co-Author: Cristina Solomon, MD MBA – Octapharma AG
    Co-Author: Sigurd Franz Knaub, PhD – Octapharma AG
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0586 - Protein S deficiency is Associated with an Increased Risk of Deep Vein Thrombosis in Pregnant Women Using Oral Contraceptive
    Room: Exhibition
    Presenting Author: Abdulrahman Algarni, PhD – Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Northern Border University, Arar P.O. Box 91431, Saudi Arabia
    Co-Author: Ezeldine K. Abdalhabib – Ezeldine K Abdalhabib Department of Clinical Laboratory Sciences, College of Applied Medical Sciences-Al Qurayyat, Jouf University, Sakaka, Saudi Arabia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0587 - Identifying Variants of AAT M358R with Increased Selectivity for Plasma Kallikrein
    Room: Exhibition
    Presenting Author: Sangavi Sivananthan (she/her/hers) – McMaster University
    Co-Author: Tyler Seto – McMaster University
    Co-Author: William P. Sheffield – McMaster University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0588 - Epitope Mapping of the α-FXIIa Allosteric Inhibitor Monoclonal Antibody 5C12
    Room: Exhibition
    Presenting Author: Sadiq Silbak, BS, MS – Department of Pathology, Case Western Reserve University
    Co-Author: Alessandro Pinheiro, PhD (he/him/his) – Division of Hematology and Oncology Department of Medicine Case Western Reserve University
    Co-Author: Michael Wallisch, PhD (he/him/his) – Aronora, Inc.
    Co-Author: Alona Merkulova – Division of Hematology and Oncology Department of Medicine Case Western Reserve University
    Co-Author: Tracey He – Department of Pathology, Microbiology and Immunology Vanderbilt University Medical Center
    Co-Author: Stephen Dickeson, PhD – Department of Pathology, Microbiology and Immunology Vanderbilt University Medical Center
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: Alvin Schmaier – Division of Hematology and Cell Therapy, Department of Medicine, University Hospitals Cleveland Medical Center
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0589 - Human transthyretin (hTTR) amyloid fibrils induce plasma clotting by activating the intrinsic pathway of blood coagulation: implications in the pathogenesis of hTTR intracardiac thrombosis
    Room: Exhibition
    Presenting Author: Alessia Dei Rossi – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Laura Acquasaliente – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Daniele Peterle – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Nicol Berti – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Alessandro Negro – Dept. of Biomedical Sciences, University of Padua, Padua, Italy
    Co-Author: Guglielmo Verona – Center for Amyloidosis, University College London, London, United Kingdom
    Co-Author: Julian Gillmore – Center for Amyloidosis, University College London, London, United Kingdom
    Co-Author: Ornella Leone – IRCCS University Hospital of Bologna, Bologna, Italy
    Co-Author: Serena Toffanin – Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, University of Padua Medical School, Padua (Italy)
    Co-Author: Raimondo De Cristofaro, MD, PhD – 1.Fondazione Policlinico Universitario A. Gemelli, IRCCS, Center for Hemorrhagic and Thrombotic Diseases and Haemophilia Center, Rome, Italy; 2. Catholic University, Translational Medicine and Surgery Department Rome, Italy
    Co-Author: Francesco Cappelli – Dept. of Experimental and Clinical Medicine, University of Florence, Florence, Italy
    Co-Author: Federico Perfetto – Dept. of Internal Medicine, Amyloidosis Research Center, University of Florence, Florence, Italy
    Co-Author: Paolo Simioni, MD, PhD (he/him/his) – Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, University of Padua Medical School, Padua (Italy)
    Co-Author: Vittorio Bellotti – Dept of Molecular Medicine, University of Pavia, Pavia, Italy
    Co-Author: Vincenzo De Filippis – University of Padua
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0590 - The control of protein binding on bio-interface by a novel coating to prevent contact activation on biomaterials
    Room: Exhibition
    Presenting Author: Haifeng Ji – University of British Columbia
    Co-Author: Tao Xu – Sichuan University
    Co-Author: Kai Yu – University of British Columbia
    Co-Author: Sreeparna Vappala, PhD (she/her/hers) – University of British Columbia
    Co-Author: Jayachandran N. Kizhakkedathu, PhD (he/him/his) – Centre for Blood Research, University of British Columbia
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0591 - Alphafold AI based applications explored as tools for predicting contact proteins PK, FXI and HK structure and evolutionary relationships
    Room: Exhibition
    Co-Author: Michal B. Ponczek, PhD DSc (he/him/his) – University of Lodz, Faculty of Biology and Environmental Protection, Department of General Biochemistry
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Presenting Author: Jonas Emsley, Phd – Nottingham Biodiscovery Institute, School of Pharmacy
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0592 - Evaluation of the Role of Skeletal Muscle Myosin as a Cofactor for Factor XI Activation of Factor XII
    Room: Exhibition
    Presenting Author: Chih Jen Yang, MD – Oregon Health & Science University
    Co-Author: John H. Griffin – Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Co-Author: Erik I. Tucker – Aronora, Inc.
    Co-Author: Christina U. Lorentz – Aronora, Inc
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: Cristina Puy, PhD – Oregon Health & Science University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0593 - Extending the Circulatory Half-life of an Engineered Kallikrein-Specific Inhibitor
    Room: Exhibition
    Presenting Author: Ghofran Al-Adimi, B.Sc. – McMaster University
    Co-Author: Louise Eltringham-Smith – Canadian Blood Services
    Co-Author: William P. Sheffield – McMaster University
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0594 - Factor XI localization in human deep venous thrombus and function of activated factor XI on mural thrombus formation under low-shear condition.
    Room: Exhibition
    Presenting Author: Nobuyuki Oguri – University of Miyazaki
    Co-Author: Toshihiro Gi, MD (he/him/his) – University of Miyazaki
    Co-Author: Kazunari Maekawa – University of Miyazaki
    Co-Author: Eiji Furukoji – University of Miyazaki
    Co-Author: Hoshimi Okawa – ONO Pharmaceutical Co., Ltd
    Co-Author: Sho Kouyama – ONO Pharmaceutical Co., Ltd
    Co-Author: Tatefumi Sakae – University of Miyazaki
    Co-Author: Minako Azuma – University of Miyazaki
    Co-Author: Yujiro Asada – Miyazaki Medical Association Hospital
    Co-Author: Atsushi Yamashita, MD, PhD – University of Miyazaki
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0595 - The profile of contact activation system proteins in human abdominal aortic aneurysm plasma- and tissue samples
    Room: Exhibition
    Presenting Author: Stephanie Thuy Duong Pham, MSc (she/her/hers) – Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark
    Co-Author: Jes Sanddal Lindholt – Department of Cardiac, Thoracic, and Vascular Surgery, Odense University Hospital, Odense, Denmark
    Co-Author: Jose Luis Martin-Ventura – IIS-Fundación Jiménez-Díaz, Universidad Autonoma de Madrid; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain
    Co-Author: Else-Marie Bladbjerg – Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark.
    Co-Author: Katrine Pilely, PhD (she/her/hers) – Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.
    Co-Author: Yaseelan Palarasah, MSc, PhD – Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0596 - Characterization of anti-polyphosphate monoclonal antibodies
    Room: Exhibition
    Presenting Author: Josepha C. Sedzro, PhD (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Alexander Scott – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Stephanie A. Smith, DVM (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: James H. Morrissey, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0597 - Specificity of contact pathway inhibitors with regard to other coagulation and fibrinolysis proteases.
    Room: Exhibition
    Presenting Author: Dougald M. Monroe, PhD – UNC Blood Research Center, Chapel Hill, NC
    Co-Author: Mike W. Henderson – UNC Blood Research Center, Chapel Hill, NC
    Co-Author: Anton Ilich, MD – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Co-Author: Rafal Pawlinski, PhD – Division of Hematology and Blood Research Center, University of North Carolina at Chapel Hill
    Co-Author: Denis F. Noubouossie – UNC Blood Research Center
    Co-Author: Nigel S. Key – Division of Hematology, University of North Carolina, Chapel Hill, NC, USA
    Coagulation and Natural Anticoagulants
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0598 - Blood Anticoagulant Impacts Endogenous Thrombin Generation in a Peripartum Population
    Room: Exhibition
    Presenting Author: Maria Cristina Bravo, PhD, PhD (she/her/hers) – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Ira Bernstein, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Matthew Gissel – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Kelley McLean, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Thomas Orfeo, PhD – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    10:45 – 12:00 ET
    OC 51.6 - Regulation of Coagulation in Critical Illness
    Room: 710A
    Moderator: Jean M. Connors, MD (she/her/hers) – Brigham and Women's Hospital
    Moderator: Cindy MM De Jong, MD – Department of Medicine - Thrombosis & Hemostasis, Leiden University Medical Center, Leiden, The Netherlands
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    10:45 – 11:00 ET
    OC 51.1 - Risk of delayed intracranial hemorrhage according to antithrombotic treatment in patients with traumatic brain injury: Systematic Review and Meta-Analysis
    Room: 710A
    Presenting Author: Ludovica Anna Cimini, MD (she/her/hers) – Vascular and Emergency Medicine-Stroke Unit, University of Perugia
    Co-Author: Elsa Giomi – UOC Pronto Soccorso e Medicina d’urgenza, Ospedale Apuane, Massa
    Co-Author: Cecilia Becattini, PhD – University of Perugia
    Co-Author: Maria Cristina Vedovati, MD – Vascular and Emergency Medicine, University of Perugia
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    11:00 – 11:15 ET
    OC 51.2 - Systematic immediate Vitamin K antagonist reversal with prothrombin complex concentrate in patients with recent mild traumatic brain injury (PREVACT): a multicenter, randomized, controlled trial.
    Room: 710A
    Presenting Author: Pierre-Marie Roy, MD, PhD (he/him/his) – Service des urgences, Centre Hospitalo-Universitaire d’Angers, Institut MITOVASC, EA 3860, Université d'Angers, Angers, FCRIN INNOVTE, France.
    Co-Author: Delphine Douillet – Emergency Department, CHU Angers
    Co-Author: Emilie Dehours – Emergency Department, CHU Toulouse, Toulouse, France.
    Co-Author: Christian Brice – Emergency Department, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
    Co-Author: Hery Andrianjafy – Emergency Department, Centre Hospitalier de Longjumeau, Longjumeau, France
    Co-Author: Albert Trinh-Duc – Emergency Department, Centre Hospitalier d’Agen, Agen, France.
    Co-Author: Sabrina Perlet – Emergency Department, Centre Hospitalier de Saint-Malo, Saint-Malo, France.
    Co-Author: Bertrand Drugeon – Emergency Department, CHU Poitiers, Poitiers, France.
    Co-Author: Nicolas Bournaud – Emergency Department, Centre Hospitalier de Montauban, Montauban, France.
    Co-Author: Elisabeth Saligari – Emergency Department, Centre Hospitalier d’Annecy, Annecy, France.
    Co-Author: Jacques Levraut – Emergency Department, CHU Nice, Université de Nice, Nice, France.
    Co-Author: Sandrine Dautheville – Emergency Department, Hôpital Tenon, APHP, Paris, France.
    Co-Author: Mahjoub Gabteni – Emergency Department, CHU Bretonneau, Tours, France.
    Co-Author: Sigismond Lasocki – Department of Anesthesia and Intensive Care, CHU Angers, Angers, France
    Co-Author: Fabrice Prunier – Department of Cardiology, CHU Angers, Angers, France
    Co-Author: Matthieu Labriffe – Radiology Department, CHU Angers, UNIV Angers, Angers, France
    Co-Author: Luc-Marie Joly – Emergency Department, CHU Rouen, Rouen, France
    Co-Author: Patricia Jabre – SAMU de Paris, Hôpital Necker, APHP, Paris, France.
    Co-Author: Jérémie Riou – Methodology and Biostatistics Department, Delegation to Clinical Research and Innovation, CHU Angers, Angers, France
    Co-Author: Karim Tazarourte – Emergency Department, Centre Hospitalier Universitaire Édouard Herriot, Hospices Civils de Lyon, Lyon, France
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    11:15 – 11:30 ET
    OC 51.3 - Dielectric blood coagulometry for evaluation of coagulation activity of blood samples from patients prescribed with direct oral anticoagulants undergoing elective surgeries
    Room: 710A
    Presenting Author: Aya Takemoto, MD – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Co-Author: Nobuyo Kondo – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Co-Author: Akiko Kitajo – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Co-Author: Hiroto Yamamoto – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Co-Author: Yudai Yamamoyo – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Co-Author: Koji Higashino – Arkray Marketing Inc
    Co-Author: Tokujiro Uchida – Department of Anesthesiology, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    11:30 – 11:45 ET
    OC 51.4 - Low thrombin inactivation capacity is an independent risk factor for cancer mortality in men: results from the Moli-sani study
    Room: 710A
    Presenting Author: Romy De Laat-Kremers, PhD – Department of Data Analysis and Artificial Intelligence, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Simona Costanzo – Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, IS, Italy
    Co-Author: Augusto Di Castelnuovo – Mediterranea Cardiocentro, Napoli, Italy
    Co-Author: Qiuting Yan – Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Sara Magnacca – Mediterranea Cardiocentro, Napoli, Italy
    Co-Author: Maria Benedetta Donati – Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy
    Co-Author: Bas de Laat, MD, PhD – Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Licia Iacoviello – Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    11:45 – 12:00 ET
    OC 51.5 - Outcomes Associated with The Use of Dual Antiplatelet Therapy in Patients Presenting with Out of Hospital Cardiac Arrest supported with Veno arterial Extracorporeal Membrane Oxygenation
    Room: 710A
    Presenting Author: Alejandra Gutierrez, MD – University of Minnesota Medical Center: University of Minnesota Health
    Co-Author: Rajat Kalra – University of Minnesota Medical Center: University of Minnesota Health
    Co-Author: Marie E. Steiner, MD, MS – The University of Minnesota
    Co-Author: Alexandra Marquez – University of Minnesota Medical Center: University of Minnesota Health
    Co-Author: Demetris Yannopoulos – University of Minnesota Medical Center: University of Minnesota Health
    Co-Author: Jason A Bartos – University of Minnesota Medical Center: University of Minnesota Health
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    14:45 – 16:00 ET
    OC 62.6 - Novel Antithrombotic Strategies
    Room: 710B
    Moderator: Georges JOURDI, PharmD, PhD (he/him/his) – Université Paris Cité and APHP. Nord
    Moderator: Deborah M. Siegal, MD MSc FRCPC – The Ottawa Hospital
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    14:45 – 15:00 ET
    OC 62.1 - Differential suppression of arterial versus venous thrombosis but preserved hemostasis in mice expressing fibrinogen that cannot support fibrin formation
    Room: 710B
    Presenting Author: Woosuk Steve Hur, PhD – University of North Carolina at Chapel Hill
    Co-Author: Tomohiro Kawano – University of North Carolina at Chapel Hill
    Co-Author: Jean Marie Mwiza, PhD (he/him/his) – University of North Carolina at Chapel Hill
    Co-Author: David S. Paul, PhD – University of North Carolina at Chapel Hill
    Co-Author: Robert H. H. Lee, PhD – University of North Carolina at Chapel Hill
    Co-Author: Emily G. Clarke – University of North Carolina at Chapel Hill
    Co-Author: Emma Bouck – University of North Carolina at Chapel Hill
    Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill
    Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill
    Co-Author: Wolfgang Bergmeier, PhD – University of North Carolina at Chapel Hill
    Co-Author: Matthew J. Flick, PhD – University of North Carolina at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    15:00 – 15:15 ET
    OC 62.2 - Antiplatelet and anticoagulant compound (APAC) restricts thromboinflammation to ameliorates myocardial ischemia reperfusion injury
    Room: 710B
    Co-Author: Sameen Fatima, MPhil – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Saira Ambreen – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Shrey Kohli, PhD – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Riitta Lassila, MD, PhD (she/her/hers) – Helsinki University Hospital, Coagulation Disorders Unit, Department of Haematology, Comprehensive Cancer Centre, and Research Program Unit in System Oncology, University of Helsinki, Helsinki, Finland
    Co-Author: Berend Isermann, PhD MD (he/him/his) – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Presenting Author: Khurrum Shahzad – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    15:15 – 15:30 ET
    OC 62.3 - A noble metal stent coating reduces thrombo-inflammatory reactions and acute stent thrombosis – an in vitro and in vivo study
    Room: 710B
    Presenting Author: Mikael Sandell, MSc (he/him/his) – KTH Royal Institute of Technology
    Co-Author: Anna Ericsson – Bactiguard AB
    Co-Author: Jonathan Al-Saadi – Karolinska Institute
    Co-Author: Billy Södervall – Bactiguard AB
    Co-Author: Erika Södergren – Bactiguard AB
    Co-Author: Stefan Grass – Bactiguard AB
    Co-Author: Javier Sanchez – Bactiguard AB
    Co-Author: Staffan Holmin – Karolinska Institute
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    15:30 – 15:45 ET
    OC 62.4 - Factor XI(a) antibody abelacimab reduces thrombus growth and propagation in a baboon model of vascular graft thrombosis.
    Room: 710B
    Presenting Author: Michael Wallisch, PhD (he/him/his) – Aronora, Inc.
    Co-Author: Yasser Khder – Anthos Therapeutics, Inc.
    Co-Author: Jennifer Johnson – Oregon Health & Science University
    Co-Author: Monica T. Hinds – Oregon Health & Science University
    Co-Author: Erik I. Tucker – Aronora, Inc.
    Co-Author: Dan Bloomfield, MD (he/him/his) – Anthos Therapeutics, Inc.
    Co-Author: Andras Gruber – Aronora, Inc.
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    15:45 – 16:00 ET
    OC 62.5 - Next-generation, dendrimer-like polyphosphate inhibitor is a safe and effective antithrombotic agent
    Room: 710B
    Presenting Author: Stephanie A. Smith, DVM (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Chanel La – Centre for Blood Research, University of British Columbia
    Co-Author: Sreeparna Vappala, PhD (she/her/hers) – University of British Columbia
    Co-Author: Raymond Adili – Bloodworks Research Institute
    Co-Author: Catherine Luke – University of Michigan
    Co-Author: Srinivas Abbina – Centre for Blood Research, University of British Columbia
    Co-Author: Haiming D. Luo – Centre for Blood Research, University of British Columbia
    Co-Author: Irina Chafeeva – Centre for Blood Research, University of British Columbia
    Co-Author: Matthew Drayton – Centre for Blood Research, University of British Columbia
    Co-Author: Louise A. Creagh – University of British Columbia
    Co-Author: Nicole Rhoads – Bloodworks Research Institute
    Co-Author: Manu Thomas Kalathottukaren – University of British Columbia
    Co-Author: Peter Henke – University of Michigan
    Co-Author: Suzana K. Straus – University of British Columbia
    Co-Author: Caigan Du – University of British Columbia
    Co-Author: Edward M Conway, MD, PhD – Centre for Blood Research, University of British Columbia
    Co-Author: Michael Holinstat, PhD – University of Michigan
    Co-Author: Charles A Haynes – Michael Smith Laboratories, Chemical & Biological Engineering, University of British Columbia
    Co-Author: James H. Morrissey, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Jayachandran N. Kizhakkedathu, PhD (he/him/his) – Centre for Blood Research, University of British Columbia
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1030 - Hemostatic Evaluation of Synthetic Platelet Nanotechnology in Rabbit Models of Dilutional Coagulopathy and Trauma
    Room: Exhibition
    Presenting Author: Ujjal Didar Singh Sekhon, PhD (he/him/his) – Haima Therapeutics
    Co-Author: Sana Syed – Haima Therapeutics
    Co-Author: Amudan J. Srinivasan, MD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Zachary Secunda – UPMC
    Co-Author: Roberto Mota – Trauma and Transfusion Medicine Research Center, University of Pittsburgh
    Co-Author: Dante Disharoon, PhD – Case Western Reserve University
    Co-Author: Baylee Traylor – Haima Therapeutics
    Co-Author: Emily Gahagan – Haima Therapeutics
    Co-Author: Jane Arthur – CSL Innovation
    Co-Author: Wilfried Krege – CSL Behring Innovation GmbH
    Co-Author: Anirban Sen Gupta, PhD (he/him/his) – Case Western Reserve University
    Co-Author: Matthew D. Neal, MD FACS (he/him/his) – University of Pittsburgh
    Co-Author: Frauke May – CSL Behring Innovation GmbH
    Co-Author: Markus Brechmann – CSL Behring Innovation GmbH
    Co-Author: Christa Pawlowski – Haima Therapeutics
    Co-Author: Michael Bruckman – Haima Therapeutics
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1031 - Assessment of Coagulation Factor Levels in LVAD Patients Following Temporary Warfarin Reversal with 4F-PCC: KVAD Study
    Room: Exhibition
    Presenting Author: Katelyn W. Sylvester, PharmD, BCPS, CACP – Brigham and Women's Hospital
    Co-Author: Jessica Grandoni – Brigham and Women's Hospital
    Co-Author: Megan Rhoten – Brigham and Women's Hospital
    Co-Author: Lara Coakley – Brigham and Women's Hospital
    Co-Author: Erin L. Matiello – Brigham and Women's Hospital
    Co-Author: Katie Frankel – Brigham and Women's Hospital
    Co-Author: Brooke Fortin – Brigham and Women's Hospital
    Co-Author: Kate Jolley – Brigham and Women's Hospital
    Co-Author: Hae Soo Park – Brigham and Women's Hospital
    Co-Author: Revital Freedman – Brigham and Women's Hospital
    Co-Author: Mandeep R. Mehra – Brigham and Women's Hospital
    Co-Author: Michael M. Givertz – Brigham and Women's Hospital
    Co-Author: Jean M. Connors, MD (she/her/hers) – Brigham and Women's Hospital
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1032 - Four-factor prothrombin complex concentrates for vitamin K antagonist reversal before urgent surgery: dosing and hemostatic efficacy in a double-blind randomized study
    Room: Exhibition
    Presenting Author: Ravindra Sarode, MD – University of Texas Southwestern Medical Center
    Co-Author: Joshua Goldstein – Massachusetts General Hospital, Harvard Medical School
    Co-Author: Gregory Simonian – Hackensack University Medical Center
    Co-Author: Truman Milling Jr – Dell Medical School, University of Texas at Austin
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1033 - Delphi consensus recommendations for neuraxial anesthesia in adults with platelet disorders and coagulation defects
    Room: Exhibition
    Presenting Author: Wynn Peterson, MD (she/her/hers) – Division of Hematology, Queen's University
    Co-Author: Rachel Martin – Unity Health Toronto, University of Toronto
    Co-Author: Donald Arnold, MD MSc (he/him/his) – McMaster University, Department of Medicine
    Co-Author: Brendon Carvalho – Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine
    Co-Author: Adam Cuker, MD, MS (he/him/his) – Department of Medicine and Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Co-Author: Drew Provan, MD – Barts and the London School of Medicine and Dentistry, Queen Mary University of London
    Co-Author: Natalia Rydz – Division of Hematology and Hematological Malignancies, Department of Medicine, University of Calgary, Calgary, AB, Canada
    Co-Author: Eliane Shore – Obstetrics & Gynecology, St. Michael's Hospital, University of Toronto
    Co-Author: David J. J. Kuter, MD, DPhil – Hematology Division, Massachusetts General Hospital, Harvard Medical School
    Co-Author: Peter Kouides, MD – Mary M. Gooley Hemophilia Centre, Rochester, NY, USA
    Co-Author: Michelle Lavin, MB, PhD (she/her/hers) – National Coagulation Centre, St. James Hospital and Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Physicians and Surgeons in Ireland (RCSI)
    Co-Author: Paula James, MD – Department of Medicine, Queen's University, Kingston, ON, Canada
    Co-Author: Dale Engen – Department of Anesthesiology and Perioperative Medicine, Queen’s University
    Co-Author: Michelle Sholzberg, MDCM, FRCPC, MSc., MDCM, FRCPC, MSc – Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, ON, Canada
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1034 - Monitoring of argatroban in critical ill patients: a prospective study comparing aPTT, point-of-care viscoelastic testing with ecarin clotting time and dTT to LC/MS/MS
    Room: Exhibition
    Presenting Author: Lars Heubner, MD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Reinhard Oertel – Institute of Clinical Pharmacology, Faculty of Medicine „Carl Gustav Carus“, Technische Universität Dresden, Dresden, Germany
    Co-Author: Andreas Güldner – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Oliver Vicent – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Oliver Tiebel – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Institute of Clinical Chemistry, Dresden, Saxony, Germany
    Co-Author: Jan Beyer-Westendorf, MD,PhD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Division of Hematology and Hemostasis, Department of Medicine I Thrombosis Research, Dresden, Saxony, Germany
    Co-Author: Bertold Renner – Institute of Clinical Pharmacology, Faculty of Medicine „Carl Gustav Carus“, Technische Universität Dresden, Dresden, Germany
    Co-Author: Thea Koch – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Peter Spieth – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1035 - Monitoring of unfractionated heparin in critical ill ICU patients: a prospective study comparing aPTT and point-of-care viscoelastic testing with IN / HI ratio to anti-Xa
    Room: Exhibition
    Presenting Author: Lars Heubner, MD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Anna Dietze – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Oliver Tiebel – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Institute of Clinical Chemistry, Dresden, Saxony, Germany
    Co-Author: Andreas Güldner – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Oliver Vicent – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Jan Beyer-Westendorf, MD,PhD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Division of Hematology and Hemostasis, Department of Medicine I Thrombosis Research, Dresden, Saxony, Germany
    Co-Author: Thea Koch – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Peter Spieth – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1037 - Bridging for chronic AVKs use with Enoxaparin vs Rivaroxaban: A long-term, single-center, controller, prospective study.
    Room: Exhibition
    Presenting Author: Josue Ruiz-Contreras – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Ivette Diaz-Cerda – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Luis F. Rubalcava-Lara, MD (he/him/his) – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Maria L. ALCIVAR GARCIA – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Pablo Garcia Chavez – Instituto Mexicano del Seguro Seguro
    Co-Author: Geraldin Gutierrez-Gomez – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Abraham Majluf-Cruz, MD, PhD (he/him/his) – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1038 - Differences in clot formation and lysis between septic patients and controls assessed by whole-blood thromboelastometry: a prospective observational study
    Room: Exhibition
    Presenting Author: Ecaterina Scarlatescu, MD PhD MSc – University of Medicine and Pharmacy "Carol Davila"
    Co-Author: Paul Y. Kim, PhD (he/him/his) – Department of Medicine, McMaster University
    Co-Author: Sergey P. Marchenko – Department of Cardiac Surgery, Pavlov First St. Petersburg Medical University, St. Petersburg, Russian Federation
    Co-Author: Dana R. Tomescu – University of Medicine and Pharmacy "Carol Davila" Bucharest Romania
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1039 - Evaluation of External Quality Assessment material for activated clotting time on point of care devices: United Kingdom National External Quality Assessment Scheme for Blood Coagulation pilot studies.
    Room: Exhibition
    Co-Author: Lilia Brown, MSc – UK NEQAS for Blood Coagulation
    Co-Author: Dianne P. Kitchen, MSc – UK NEQAS BC
    Presenting Author: Ian Jennings – UK NEQAS BC
    Co-Author: Steve Kitchen, PhD – Sheffield Haemophilia and Thrombosis Centre
    Co-Author: Isobel Walker – UK NEQAS BC
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1041 - Evaluation of external quality assessment material on the renovated point of care device, United Kingdom National External Quality Assessment Scheme for Blood Coagulation studies.
    Room: Exhibition
    Co-Author: Lilia Brown, MSc – UK NEQAS for Blood Coagulation
    Co-Author: Dianne P. Kitchen, MSc – UK NEQAS BC
    Presenting Author: Ian Jennings – UK NEQAS BC
    Co-Author: Steve Kitchen, PhD – Sheffield Haemophilia and Thrombosis Centre
    Co-Author: Isobel Walker – UK NEQAS BC
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1042 - Impact of preoperative anticoagulation on perioperative bleeding in patients undergoing cardiopulmonary bypass for heart and lung transplantation
    Room: Exhibition
    Presenting Author: Kristi Schwietz, PharmD – Brigham and Women's Hospital
    Co-Author: Dareen M. Kanaan – Brigham and Women's Hospital
    Co-Author: Katelyn W. Sylvester, PharmD, BCPS, CACP – Brigham and Women's Hospital
    Co-Author: Kenneth E. Lupi – Brigham and Women's Hospital
    Co-Author: Jean M. Connors, MD (she/her/hers) – Brigham and Women's Hospital
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1043 - Efficacy and Safety of Three-factor Prothrombin Complex Concentrates For The Management of Oral Direct Factor Xa Inhibitor Associated Major Bleeding.
    Room: Exhibition
    Co-Author: PAKPOOM RASMEEHIRUN, MD (he/him/his) – Phramongkutklao Hospital
    Presenting Author: Rattapan Lamool, MD (he/him/his) – Division of Hematology, Department of Medicine, Phramongkutklao Hospital and College of Medicine
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1046 - Early Goal-directed Hemostatic Therapy (EGDHT) for Severe Acute Bleeding Management in the Intensive Care Unit
    Room: Exhibition
    Co-Author: MARCUS LANCE – 7. Aga Khan University, Department of Anesthesiology, Nairobi, Kenya
    Co-Author: Klaus Goerlinger – TEM Innovations GmbH/Werfen PBM
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1047 - A patient with severe, refractory ITP and GI bleeding is kept hemodynamically stable over days with a combination therapy of tranexamic acid, recombinant FVIIa, F XIII and red blood cell concentrates
    Room: Exhibition
    Presenting Author: Wolfgang Korte, MD, Prof – Center for Laboratory Medicine, Hemophilia- and Hemostasis Center St. Gallen
    Co-Author: Susann Endermann – Dept of Anesthesiology, Kantonsspital St. Gallen
    Co-Author: Thomas Ruckstuhl – Dept of Anesthesiology, Kantonsspital St. Gallen
    Co-Author: Lukas Graf – Center for Laboratory Medicine, Hemophilia- and Hemostasis Center St. Gallen
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1048 - Implementation of Electronic Medical Records in a resource-limited Haematology department in North-West Nigeria
    Room: Exhibition
    Presenting Author: Saidu Y. YAKUBU, MD (he/him/his) – Barau Dikko Teaching Hospital Kaduna Nigeria
    Co-Author: Livingstone G. Dogara – BDTH Kaduna
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1049 - Immune modulatory function of desialylated platelets containing FVIII in FVIII immune responses in hemophilia A mice
    Room: Exhibition
    Co-Author: Yingyu Chen, PhD – Department of Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital
    Co-Author: Feng Xue, MD – Institute of haematology and Blood Diseaes Hospital, Chinese Academy of Medical Sciences and Pkeing Union Medical College
    Co-Author: Jocelyn Schroeder, BS – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Presenting Author: Qizhen Shi, MD, PhD – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1050 - Putative Collagen IV and Heparin-binding Sites Cooperatively Regulate Extravascular Binding of Factor IX in Hemophilia B Mice
    Room: Exhibition
    Co-Author: Douglas Annis – Department of Medicine, Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin School of Medicine and Public Health
    Co-Author: Pamela Westmark – Department of Medicine, Division of Hematology, Medical Oncology and Palliative Care, Univerity of Wisconsin School of Medicine and Public Health
    Presenting Author: John P. Sheehan, MD – Department of Medicine, Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin School of Medicine and Public Health
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1051 - Tyrosine Under-Sulfation of Factor VIII Results in T-Cell Response and Decreased Affinity Towards Thrombin in a Model System
    Room: Exhibition
    Presenting Author: Philip J. Olivares, PhD (he/him/his) – U.S. Food and Drug Administration
    Co-Author: Vijaya Simhadri – U.S. Food and Drug Administration
    Co-Author: Louis Hopkins – U.S. Food and Drug Administration
    Co-Author: Joseph R. McGill – U.S. Food and Drug Administration
    Co-Author: Haarin Chun – U.S. Food and Drug Administration
    Co-Author: Zuben E. Sauna – U.S. Food and Drug Administration
    Co-Author: Andrey G. Sarafanov, PhD – U.S. Food and Drug Administration
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1052 - Evaluating the individual risk of venous thrombo-embolism in patients with liver cirrhosis: Usefulness of in vivo and ex vivo thrombin generation parameters
    Room: Exhibition
    Presenting Author: Cindy Pereira Portela, MD Student – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Montserrat Fraga – Division of Gastroenterology and Hepatology, Lausanne University Hospital and University of Lausanne
    Co-Author: Maxime Grégoire G. Zermatten – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Debora Bertaggia Calderara, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Alessandro Aliotta, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Élise Mdawar-Bailly – Division of Gastroenterology and Hepatology, Lausanne University Hospital and University of Lausanne
    Co-Author: Florent Artru – Institute of Liver Studies, King’s College Hospital
    Co-Author: Darius Moradpour – Division of Gastroenterology and Hepatology, Lausanne University Hospital and University of Lausanne
    Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1053 - Protective role of the SerpinE2 PN-1 in renal disease
    Room: Exhibition
    Presenting Author: Junjie Yu, Master of Science – Inserm U1148
    Co-Author: Christos E CHADJICHRISTOS – Inserm U1155
    Co-Author: Yacine BOULAFTALI – Inserm U1148
    Co-Author: Marie-Christine BOUTON – Inserm U1148
    Co-Author: Christos CHATZIANTONIOU – Inserm U1155
    Co-Author: Véronique AROCAS – Inserm U1148
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1054 - A Multi-Center, Stratification-Randomized , Double-Blind, Placebo-Controlled, Phase III Clinical Trial of Topical Recombinant Human Thrombin for Intraoperative Hemostasis
    Room: Exhibition
    Presenting Author: Jun Yu – The First Hospital of Zhejiang University School of Medicine
    Co-Author: Sheng Yan – The Second Hospital of Zhejiang University School of Medicine
    Co-Author: Chaoyong Tu – Lishui Central Hospital
    Co-Author: Chengyou Du – The First Affiliated Hospital of Chongqing Medical University
    Co-Author: Jia Luo – Hunan Cancer Hospital
    Co-Author: Jingfeng Liu – Mengchao Hepatobiliary Hospital of Fujian Medical University
    Co-Author: Tianqi Liu – Jiangbin Hospital of Guangxi Zhuang Autonomous Region
    Co-Author: Qiang Liu – Liuzhou People's Hospital
    Co-Author: Jun Liu – Guizhou Provicial People’s Hospital
    Co-Author: Xuehua Li – Liaocheng People's Hospital
    Co-Author: Lianchen Wang – The Third People's Hospital of Hainan Province
    Co-Author: Zheping Fang – Taizhou Hospital of Zhejiang Province
    Co-Author: Weimin Yi – Hunan Provincial People's Hospital
    Co-Author: Yajin Chen – Sun Yat-sen Memorial Hospital of Sun Yat-sen University
    Co-Author: Qinglong Li – The Second Xiangya Hospital of Central South University
    Co-Author: Yong Ni – Shenzhen Second People's Hospital
    Co-Author: Jincai Wu – Hainan Provincial People's Hospital
    Co-Author: Changjiang Qin – Huaihe Hospital of Henan University
    Co-Author: Yuanlong Gu – The Third People's Hospital of Wuxi
    Co-Author: Zheng Lu – The First Affiliated Hospital of Bengbu Medical College
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1055 - Chronic anticoagulation in patients with liver failure: A single-center cohort study.
    Room: Exhibition
    Co-Author: Maria L. ALCIVAR GARCIA – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Geraldin Gutierrez-Gomez – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Pablo Garcia Chavez – Instituto Mexicano del Seguro Seguro
    Co-Author: Luis F. Rubalcava-Lara, MD (he/him/his) – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Josue Ruiz-Contreras – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Co-Author: Ivette Diaz-Cerda – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Presenting Author: Abraham Majluf-Cruz, MD, PhD (he/him/his) – Unidad médica de investigación de trombosis, hemostasia y aterogénesis, Instituto Mexicano del Seguro Social
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1056 - In situ Pulmonary Thrombosis is Regulated by Integrin αIIbβ3-dependent Platelet Procoagulant Activity
    Room: Exhibition
    Presenting Author: Tomasz Brzoska, PhD (he/him/his) – University of Pittsburgh
    Co-Author: Tomasz W. Kaminski, PharmD – University of Pittsburgh
    Co-Author: Omika Katoch – University of Pittsburgh
    Co-Author: Prithu Sundd, PhD (he/him/his) – University of Pittsburgh
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1057 - VWF type 2N variant markedly enhances FVIII levels when both proteins are expressed in platelets
    Room: Exhibition
    Presenting Author: Jocelyn Schroeder, BS – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Co-Author: Hongyin Yu – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Co-Author: Jessica Rapten – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Co-Author: Scot Fahs – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Co-Author: Robert Montgomery – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Co-Author: Qizhen Shi, MD, PhD – Medical College of Wisconsin, Versiti Blood Research Institute, Children's Research Institute
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1058 - Mechanical properties of fibrin clots from patients with acute-on-chronic liver failure are inferior to those of healthy individuals and patients with sepsis without underlying liver disease
    Room: Exhibition
    Presenting Author: Ellen Driever – Surgical Research Laboratory, Department of Surgery, Univeristy Medical Center Groningen, Groningen, the Netherlands
    Co-Author: Iain Muntz – Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, The Netherlands
    Co-Author: Vishal Patel – Institute of Liver Studies, King’s College Hospital NHS Foundation Trust, London, United Kingdom
    Co-Author: Jelle Adelmeijer – UMCG
    Co-Author: William Bernal – Institute of Liver Studies, King’s College Hospital NHS Foundation Trust, London, United Kingdom
    Co-Author: Gijsje H. Koenderink – Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands
    Co-Author: Ton Lisman, PhD – UMCG
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1059 - Single Amino Acid Substitutions of an Antibody Specific for a Non-Active Site of Activated Protein C (APC) Yielded an Antibody Library Capable of Modulating and Uncoupling APC Pleiotropic Functions
    Room: Exhibition
    Presenting Author: Derek S. Sim, PhD – Coagulant Therapeutics
    Co-Author: Meenal Shukla – Scripps Research
    Co-Author: Cornell R. Mallari – Coagulant Therapeutics
    Co-Author: Doug Schneider – Coagulant Therapeutics
    Co-Author: Maxine Bauzon – Coagulant Therapeutics
    Co-Author: Terry W. Hermiston – Coagulant Therapeutics
    Co-Author: Laurent O. Mosnier, PhD – Scripps Research
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1060 - Thrombin generation and fibrin clot structure in nephrotic patients with primary glomerular disorders
    Room: Exhibition
    Co-Author: Jean Terrier – Clinical Pharmacology and Toxicology Service, Anesthesiology Pharmacology and Intensive Care Department, Geneva University Hospitals, Geneva, Switzerland
    Co-Author: Rita Marchi – UNIGE
    Co-Author: Tomoko Takano – Division of Nephrology and research institute, Department of Medicine, McGill University Health Center, Montreal, QC, Canada
    Co-Author: Ratna Samanta – 4Division of Nephrology, Department of Medicine, McGill University Health Center, Montreal, QC, Canada
    Co-Author: Sophie De Seigneux – 6Division of Nephrology, Geneva University Hospitals, Geneva, Switzerland
    Co-Author: Alessandro Casini, MD – Division of Angiology and Hemostasis, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland
    Presenting Author: Thomas A. Mavrakanas, MD, MSc – Division of Nephrology, Department of Medicine, McGill University Health Center and Research Institute, Montreal, QC, Canada
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1061 - Impact of FII, FVIII, or FIX deficiency on bone mineralization in a zebrafish model
    Room: Exhibition
    Presenting Author: Brigitte Tardy, MD PhD – Université Jean Monnet Saint-Étienne, CHU Saint-Étienne, Centre de traitement de l'hémophilie, Mines Saint-Etienne, INSERM, SAINBIOSE U1059, F-42023 SAINT-ÉTIENNE, FRANCE
    Co-Author: Nam Do khoa – Azelead, 377 rue du Pr Blayac, Montpellier, France
    Co-Author: Aurélie Montmartin – Université Jean Monnet Saint-Étienne, Mines Saint-Etienne, INSERM, SAINBIOSE U1059, F-42023, SAINT-ÉTIENNE, FRANCE
    Co-Author: Karima Kissa – Azelead, 377 rue du Pr Blayac, Montpellier, France
    Co-Author: Pauline Damien – Université Jean Monnet Saint-Étienne, CHU Saint-Étienne, CIC1408 , Mines Saint-Etienne, INSERM, SAINBIOSE U1059, F-42023 SAINT-ÉTIENNE, FRANCE
    Co-Author: Bernard Tardy – Université Jean Monnet Saint-Étienne, CHU Saint-Étienne, CIC1408 , Mines Saint-Etienne, INSERM, SAINBIOSE U1059, F-42023 SAINT-ÉTIENNE, FRANCE
    Co-Author: Laura Fontenille – Azelead, 377 rue du Pr Blayac, Montpellier, France
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1062 - Exogenous warfarin intoxication associated with Munchaüsen Syndrome
    Room: Exhibition
    Presenting Author: Alessandra N. L Prezotti, MD, MsC, pHD (she/her/hers) – Centro de Hematologia e Hemoterapia do Espirito Santo (HEMOES)
    Co-Author: Antonio Rocha-Neto – HEMOES
    Co-Author: Maria Orletti – HEMOES
    Co-Author: Debora Rocha – Centro de Hematologia e Hemoterapia do Espirito Santo (HEMOES)
    Co-Author: Juliana Duarte – HEMOES
    Co-Author: Sibia Marcondes – HEMOES
    Co-Author: Danielle Ribeiro – HEMOES
    Co-Author: Aline Liparizi – HEMOES
    Co-Author: Pedro Prezotti – HEMOES
    Co-Author: Andre Prezotti – HEMOES
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1063 - In vitro fibrinogen concentrate supplementation in patients with end-stage liver disease improves functional clot quality
    Room: Exhibition
    Presenting Author: Anna Tobiasch, MSc – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Johannes Bösch, MD – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Moritz Tobiasch – Tirol Kliniken Hall in Tirol, Department of Internal Medicine I
    Co-Author: Mirjam Bachler, PhD – University Hospital Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Volker Schäfer – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Philipp Lichtenberger – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Martin Hermann – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine
    Co-Author: Heinz Zoller – Medical University Innsbruck, Department of Internal Medicine I
    Co-Author: Dietmar Fries – Medical University Innsbruck, Department of Anaesthesiology and Intensive Care Medicine, Division of Critical Care Medicine
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1065 - Microvesicles display opposite coagulolytic balances according to their cellular origin and activation status
    Room: Exhibition
    Co-Author: Akhil Antony Konkoth, MSc – Aix-Marseille University
    Co-Author: Amandine Bonifay – Aix-Marseille University
    Co-Author: Corinne Chareyre – Aix-Marseille University
    Co-Author: Evelyne Abdili – Biogenopole, APHM
    Co-Author: Lea Plantureux – Aix-Marseille University
    Co-Author: Stéphane Robert – Aix-Marseille University
    Co-Author: Corentin FRANCO – Biocytex
    Co-Author: Tarik BOURICHE – Biocytex
    Co-Author: Sylvie Cointe – Aix-Marseille University
    Co-Author: Philippe Poncelet – Stago
    Presenting Author: Françoise Dignat-George – Aix-Marseille University
    Co-Author: Rory R. Koenen, PhD (he/him/his) – Maastricht University
    Co-Author: Romaric Lacroix – Aix-Marseille University
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1066 - The Effects of Polystyrene Microplastics on Thrombosis
    Room: Exhibition
    Presenting Author: Golzar Mobayen, MSc – Centre for Haematology, Imperial College London, UK
    Co-Author: Eric Auyang – Imperial College London
    Co-Author: Wayne Mitchell – Imperial College London
    Co-Author: Deepa J. Arachchillage, MD – Imperial College London
    Co-Author: Stephanie Wright – Imperial College London
    Co-Author: Thomas McKinnon, BSc, PhD – Imperial College London
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1067 - Quantification of Functional Tissue Factor Activity on Microvesicles During the Peripartum Period
    Room: Exhibition
    Presenting Author: Meghan Fondakowski – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Thomas Orfeo, PhD – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Ira Bernstein, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Matthew Gissel – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Kelley McLean, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Maria Cristina Bravo, PhD, PhD (she/her/hers) – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1069 - A standardized approach in enumerating microparticles in the Framingham Heart Study using quantitative flow cytometry
    Room: Exhibition
    Presenting Author: Bongani B. Nkambule – University of KwaZulu-Natal
    Co-Author: Robin E. Pashek – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Mellissa Chan – National Hear, Lung and Blood Institute, the Framingham Heart Study
    Co-Author: Andrew D. D. Johnson, PhD (he/him/his) – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1070 - Small and large extracellular vesicles have different tissue factor activity in cancer, sepsis, and COVID-19
    Room: Exhibition
    Presenting Author: Ana T. A Sachetto, PhD – University of North Carolina at Chapel Hill
    Co-Author: Sierra J. Archibald – University of North Carolina at Chapel Hill
    Co-Author: Yohei Hisada, PhD – University of North Carolina at Chapel Hill
    Co-Author: Axel Rosell – Karolinska Institutet
    Co-Author: Sebastian Havervall – Karolinska Institutet
    Co-Author: Nick van Es, MD PhD (he/him/his) – Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands
    Co-Author: Rienk Nieuwland – University of Amsterdam
    Co-Author: Robert A. Campbell, PhD – University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Co-Author: Elizabeth A. Middleton, MD – University of Utah
    Co-Author: Matthew T. Rondina, MD – Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA; 4George E. Wahlen Department of Veterans Affairs Medical Center, Geriatric Research, Education, and Clinical Center; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Co-Author: Charlotte Thålin – Karolinska Institutet
    Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1071 - A single-domain antibody enhancing protein S activity reduces vaso-occlusion in a murine model of sickle cell disease
    Room: Exhibition
    Presenting Author: Claire Auditeau, PharmD – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Thiago T. Maciel – Institut Imagine, INSERM U1163, Université Paris Cité, Laboratory of Excellence GR-Ex, Paris, France
    Co-Author: Josepha C. Sedzro, PhD (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Camille Roussel – Biologie Intégrée du Globule Rouge, Université de Paris Cité, Paris, France
    Co-Author: Aurélie Fricot-Montsinjon – Biologie Intégrée du Globule Rouge, Université de Paris Cité, Paris, France
    Co-Author: Mariem Khamari – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Ivan Peyron, PhD (he/him/his) – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Olivier D. Christophe – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Peter J. Lenting, PhD – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Cécile V. Denis, PhD – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Delphine Borgel – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Co-Author: François Saller – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay, Le Kremlin-Bicêtre, France
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1072 - A Novel Factor VIII Specific APC Resistance Assay
    Room: Exhibition
    Presenting Author: Johnathan J. Morris, PhD (he/him/his) – Children's Hospital of Philadelphia
    Co-Author: Cristina Martos-Rus – Children's Hospital of Philadelphia
    Co-Author: Lindsey A. George, MD – University of Pennsylvania
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1073 - Endothelial Cell-Dependent Activated Protein C Formation is Significantly Decreased in Hereditary Protein C Deficiency Regardless of Underlying Gene Variant and Residual Activity in Plasma
    Room: Exhibition
    Presenting Author: Hannah L. McRae – Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Nadine Schwarz, MS – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Jens Müller – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Sebastian F. Eckert – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Johannes Oldenburg, MD (he/him/his) – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Co-Author: Sara Reda – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Bernd Pötzsch – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Heiko Rühl – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1074 - Population pharmacokinetics of subcutaneous protein C concentrate in patients with protein C deficiency
    Room: Exhibition
    Co-Author: Liang-Hui Chu – Takeda Development Center Americas, Inc., Cambridge, MA, USA
    Co-Author: Inmaculada C. Sorribes – Certara, Inc., Princeton, NJ, USA
    Co-Author: Adekemi Taylor – Certara, Inc., Princeton, NJ, USA
    Co-Author: Jennifer Schneider – Certara, Inc., Princeton, NJ, USA
    Presenting Author: Zhaoyang Li, PhD (she/her/hers) – Takeda Development Center Americas, Inc., Cambridge, MA, USA
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1075 - APC Response Rates in Factor V Leiden Carriers Correlate with Thrombotic Risk Independent from Endothelial Properties: Results from an Endothelial Cell-based Ex Vivo Model of the Protein C Pathway
    Room: Exhibition
    Presenting Author: Nadine Schwarz, MS – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Jens Müller – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Hannah L. McRae – Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Johannes Oldenburg, MD (he/him/his) – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Co-Author: Bernd Pötzsch – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Heiko Rühl – Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1076 - Congenital protein C deficiency is associated with prothrombotic plasma fibrin clot phenotype
    Room: Exhibition
    Co-Author: Anna Weronska – Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland
    Co-Author: Michał Ząbczyk, PhD – Jagiellonian University Medical College
    Co-Author: Pilar Medina – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Co-Author: Adrianna Klajmon – John Paul II Hospital
    Presenting Author: Anetta Undas, MD PhD – Department of Thromboembolic Diseases, Institute of Cardiology, Jagiellonian University Medical College, Krakow
    Co-Author: Ewa Wypasek – John Paul II Hospital
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1077 - A novel C238G, PROC mutation in patients with thromboembolism, causes intracellular protein retention
    Room: Exhibition
    Presenting Author: Pansakorn Tanratana, MD, PhD – Department of Pharmacology, Faculty of Science, Mahidol University
    Co-Author: Karnsasin Seanoon, PhD – Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Co-Author: Praguywan Kadegasem – Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University
    Co-Author: Ampaiwan Chuansumrit – Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Co-Author: Nongnuch Sirachainan, MD – Faculty of Medicine Ramathibodi hospital, Mahidol University, Bangkok, Thailand
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1078 - Severe Thromboembolic Events in A Patient With Protein C and Protein S Heterozygous Deficiencies
    Room: Exhibition
    Presenting Author: Canan Albayrak, MD (she/her/hers) – Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1079 - Evaluation of the automated LiaphenTM Protein C Antigen (PCAg) Assay Kit on the Sysmex CN-6500 Analyser
    Room: Exhibition
    Co-Author: Richard Kirby – Nottingham University Hospitals NHS Trust - QMC Campus
    Presenting Author: Krishna J. Ram, BSc – Sysmex UK
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1080 - Clinical Course and management of patients with emergency surgeries treated with direct oral anticoagulants or vitamin K antagonists – Results of the German prospective RADOA-registry
    Room: Exhibition
    Presenting Author: Jana Last, MD – Deutsches Herzzentrum der Charité (DHZC) Berlin, Germany
    Co-Author: Edelgard Lindhoff-Last – Cardiology Angiology Centre Bethanien Hospital (CCB), Frankfurt Germany
    Co-Author: Ingvild Birschmann – Herz- und Diabeteszentrum Nordrhein-Westfalen
    Co-Author: Simone Lindau – Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany
    Co-Author: Stavros Konstantinides – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University
    Co-Author: Oliver Grottke, MD, PhD – Department of Anaesthesiology, RWITH Aachen University Hospital, Aachen, Germany
    Co-Author: Ulrike Nowak-Göttl – Thrombosis & Haemostasis Treatment Centre, University Hospital Schleswig-Holstein, Germany
    Co-Author: Barbara Zydek – Coagulation Research Centre Bethanien Hospital, Frankfurt, Germany
    Co-Author: Christian von Heymann – Department of Anaesthesia, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Vivantes Klinikum im Friedrichshain, Berlin, Germany
    Co-Author: Jan Beyer-Westendorf, MD,PhD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Division of Hematology and Hemostasis, Department of Medicine I Thrombosis Research, Dresden, Saxony, Germany
    Co-Author: Sebastian Schellong – Medical Department 2, Municipal Hospital, Dresden, Germany
    Co-Author: Patrick Meybohm – Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany
    Co-Author: Andreas Greinacher – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald, Germany
    Co-Author: Eva Herrmann – Institute of Biostatistics and Mathematical Modelling, Goethe University Frankfurt, Frankfurt, Germany
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1081 - Identification of related molecular biological effects on two novel point mutations in inherited antithrombin deficiency
    Room: Exhibition
    Co-Author: Yeu-Chin Chen, MD – Hemophilia care & research center, Division of Hematology/Oncology, Tri-Service General Hospital, National Defense Medical Centerr, Taipei, Taiwan
    Presenting Author: Shiue-Wei Lai, PhD – Division of Hematology/Oncology, Department of Internal Medicine, Tri-service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Co-Author: Chia-Yau Chang, assistant professor – 1. Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University; 2. Division of Pediatric Hematology and Oncology, Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan.
    Co-Author: Shu-Hsia Hu – Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan.
    Co-Author: Chiou-Píng Huang – Hemophilia care & research center, Division of Hematology/Oncology, Tri-Service General Hospital, National Defense Medical Center
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1082 - Comprehensive coagulation activity assessments of escalating doses of intravenous APAC, a heparin proteoglycan mimic, in pigs
    Room: Exhibition
    Presenting Author: Annukka Jouppila, MSc – Clinical Research Institute HUCH
    Co-Author: Zsuzsa Bagoly, MD, PhD – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Co-Author: Rita Orbán-Kálmándi – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Co-Author: Linda Lóczi – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Co-Author: Dóra Bomberák – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Co-Author: Ádám Deák – Department of Operative Techniques and Surgical Research, University of Debrecen, Debrecen, Hungary
    Co-Author: Ádám Mátrai – Department of Operative Techniques and Surgical Research, University of Debrecen, Debrecen, Hungary
    Co-Author: Norbert Németh – Department of Operative Techniques and Surgical Research, University of Debrecen, Debrecen, Hungary
    Co-Author: Riitta Lassila, MD, PhD (she/her/hers) – Helsinki University Hospital, Coagulation Disorders Unit, Department of Haematology, Comprehensive Cancer Centre, and Research Program Unit in System Oncology, University of Helsinki, Helsinki, Finland
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1083 - Effect of Combining Antiplatelet Therapy with Anticoagulation without A Definitive Indication in Patients with Chronic Liver Disease
    Room: Exhibition
    Presenting Author: Amber Afzal, MD, MSCI – Washington University in St Louis
    Co-Author: Luo Suhong – Veterans Medical Affairs, St Louis, MO
    Co-Author: Jordan K. Schaefer, MD – Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Health
    Co-Author: Kristen Sanfilippo, MD, MPHS (she/her/hers) – Washington Univesrity
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1086 - Time in therapeutic range after an event: where we started from and where are we going?
    Room: Exhibition
    Presenting Author: Mónica Fernández Pérez, MD (she/her/hers) – Hospital Universitario de Araba
    Co-Author: Laura Salcedo – Hospital Universitario de Araba
    Co-Author: Maider Ezkurra – Hospital Universitario de Araba
    Co-Author: Amaia Pradera – Hospital Universitario de Araba
    Co-Author: Angel Pereda – Hospital Universitario Araba
    Co-Author: Carlos Pison – Hospital Universitario de Araba
    Co-Author: Ana Vega – Hospital Universitario de Araba
    Co-Author: Ariane Unamunzaga – Hospital Universitario de Araba
    Co-Author: Laida Cuevas – Hospital Universitario de Araba
    Co-Author: Xabier Gutierrez – Hospital Universitario de Araba
    Co-Author: Buenaventura Buendia – Hospital Universitario de Araba
    Co-Author: Miren Gabilondo – Hospital Universitario Araba
    Co-Author: Diego Robles – Hospital Universitario de Araba
    Co-Author: Carlos de Miguel – Hospital Universitario de Araba
    Co-Author: Francisco Rodriguez – Hospital Universitario de Araba
    Co-Author: Jose Maria Guinea – Hospital Universitario Araba
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1087 - An Enoxaparin Obtained From Bovine Heparin is Equivalent to the Original Drug From Porcine Origin
    Room: Exhibition
    Co-Author: Felipe Bezerra – UFRJ
    Co-Author: Ana M F Tovar – UFRJ
    Co-Author: Gabrielly C T Valle – UFRJ
    Co-Author: Eduardo P Vilanova – UFRJ
    Co-Author: Paulo A. S. Mourão – UFRJ
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1088 - The effect of DOAC-Stop on lupus anticoagulant testing in plasma patients receiving direct oral anticoagulant
    Room: Exhibition
    Co-Author: Adrian Klepczyk – John Paul II Hospital
    Co-Author: Michał Ząbczyk, PhD – Jagiellonian University Medical College
    Co-Author: Elżbieta Papuga-Szela – John Paul II Hospital
    Presenting Author: Anetta Undas, MD PhD – Department of Thromboembolic Diseases, Institute of Cardiology, Jagiellonian University Medical College, Krakow
    Co-Author: Ewa Wypasek – John Paul II Hospital
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1089 - Impact of scorpion venoms on the control of thrombotic disease
    Room: Exhibition
    Presenting Author: Jarred Williams – University of Reading
    Co-Author: Sakthivel Vaiyapuri – University of Reading
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1090 - Modelling the effects of 4-factor prothrombin complex concentrate for the management of factor Xa inhibitor-associated bleeding
    Room: Exhibition
    Co-Author: Ineke Muir – CSL Innovation Ltd Pty
    Co-Author: Eva Herzog – CSL Behring
    Co-Author: Markus Brechmann – CSL Behring Innovation GmbH
    Presenting Author: Oliver Ghobrial – CSL Behring
    Co-Author: Alireza Rezvani-Sharif – CSL Ltd Pty
    Co-Author: Maureane Hoffman – Duke University School of Medicine
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1091 - A novel function of Protein S in clot retraction
    Room: Exhibition
    Presenting Author: Narender Kumar, Doctor of Philosophy – LSUHSC
    Co-Author: Alaina Guilbeau – LSUHSC
    Co-Author: Vijaya Pilli – LSUHSC
    Co-Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1092 - Identification of amplifying pathways of thrombin generation in a novel mouse whole blood assay
    Room: Exhibition
    Co-Author: Jun Wan, PhD (he/him/his) – Cyrus Tang Hematology Center, Soochow University
    Co-Author: Pansakorn Tanratana, MD, PhD – Department of Pharmacology, Faculty of Science, Mahidol University
    Co-Author: Mark Roest, PhD (he/him/his) – Department of Platelet pathophysiology, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Andras Gruber – Aronora, Inc.
    Co-Author: Rafal Pawlinski, PhD – Division of Hematology and Blood Research Center, University of North Carolina at Chapel Hill
    Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill
    Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill
    Presenting Author: Steven P. Grover, PhD – Division of Hematology and Blood Research Center, University of North Carolina, Chapel Hill
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1093 - Impact of the procoagulant « fingerprint » of cancer cells on the structure of fibrin clot formed in tumor microenvironment
    Room: Exhibition
    Co-Author: Chi Mai Tran Huong – Diagnostica STAGO
    Co-Author: Noémie Mourot – INSERM
    Co-Author: Beshoy Faltas – INSERM
    Co-Author: Elisabeth Mbemba – INSERM
    Co-Author: Ismail Elalamy – Medicine Sorbonne University
    Co-Author: Michele Sabbah – INSERM
    Co-Author: Jawed Fareed – Loyola University Medical center
    Presenting Author: Patrick Van Dreden, PhD – Clinical Research Department, Diagnostica Stago
    Co-Author: Grigorios Gerotziafas – Research Group "Cancer - Hemostasis - Angiogenesis" Thrombosis Center
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1094 - Multi-technique study of the role of fibrinogen and thrombin in clot formation and structure
    Room: Exhibition
    Co-Author: Heather Belcher – Eastern Carolina University
    Presenting Author: Rebecca Risman – Rutgers University
    Co-Author: Ranjini Ramanujam, MS – Rutgers University
    Co-Author: Valerie Tutwiler, PhD – Rutgers-State University of New Jersey
    Co-Author: Nathan Hudson – Eastern Carolina University
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1095 - Direct measurement of citrated blood recalcification in microfluidic flow chamber
    Room: Exhibition
    Presenting Author: Taisia Shepeliuk, PharmD (she/her/hers) – University of Pennsylvania
    Co-Author: Anastasia Masaltseva – Department of Physics at Lomonosov Moscow State University
    Co-Author: Fazoil I. Ataullakhanov – Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Co-Author: Ekaterina Grishchuk – Department of Physiology, Perelman School of Medicine, University of Pennsylvania
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1097 - Cost of major thrombotic cardiovascular events (MTCVE) among US patients with and without end-stage kidney disease (ESKD)
    Room: Exhibition
    Co-Author: Lori D. Bash – Merck & Co., Inc.
    Co-Author: Nicholas S. Roetker – Hennepin Healthcare Research Institute
    Co-Author: Alejandro Victores – Merck & Co., Inc.
    Co-Author: Dena Ramey – Merck & Co., Inc.
    Co-Author: James B. Wetmore – Chronic Disease Research Group (CDRG)
    Presenting Author: Marc P. Bonaca, MD MPH FAHA FACC (he/him/his) – University of Colorado School of Medicine
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1098 - Regulation of Protein S gene expression by hypoxia inducible factor 1 α and estrogen receptor
    Room: Exhibition
    Presenting Author: Mohammad Mohammad, Doctor of Philosophy – LSUHSC
    Co-Author: Vijaya Pilli – LSUHSC
    Co-Author: Manoj Kumar – LSUHSC
    Co-Author: Alaina Guilbeau – LSUHSC
    Co-Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1100 - Effects of COVID-19 vaccination on pro-coagulant state of a Protein S-deficient pediatric patient: new hope for treatment of the deficiency
    Room: Exhibition
    Co-Author: Diana Polania-Villanueva – LSUHSC
    Co-Author: Manoj Kumar – LSUHSC
    Co-Author: Lekha Thangada – LSUHSC
    Co-Author: Jone Garai – LSUHSC
    Co-Author: Jovanny Zabaleta – LSUHSC
    Presenting Author: Rinku Majumder, PhD (she/her/hers) – Department of Interdisciplinary Oncology, LSUHSC
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1101 - Assessing the Antithrombotic Effects of Isoquercetin in Sickle Cell Disease
    Room: Exhibition
    Presenting Author: Bindu Parachalil Gopalan, MSc, PhD – Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health
    Co-Author: Maria A. Lizarralde-Iragorri – Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health
    Co-Author: Mai Hill – National Heart, Lung and Blood Institute, National Institutes of Health
    Co-Author: Brenda Merriweather – National Heart, Lung and Blood Institute, National Institutes of Health
    Co-Author: Jennifer Brooks – National Heart, Lung and Blood Institute, National Institutes of Health
    Co-Author: Ruth Pierre Charles – National Heart, Lung and Blood Institute, National Institutes of Health
    Co-Author: Rafael Villasmil – FlowCytometry Core Facility, National Eye Institute, National Institutes of Health
    Co-Author: Neal Jeffries – Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health
    Co-Author: Arun S. Shet – Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health
    Coagulation and Natural Anticoagulants
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1102 - Evaluation of the ability of commercial ELISAs to measure tissue factor in human plasma
    Room: Exhibition
    Presenting Author: Ana T. A Sachetto, PhD – University of North Carolina at Chapel Hill
    Co-Author: Sierra J. Archibald – University of North Carolina at Chapel Hill
    Co-Author: Ravi Bhatia – University of Alabama at Birmingham
    Co-Author: Yohei Hisada, PhD – University of North Carolina at Chapel Hill
    Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:15 – 11:30 ET
    OC 70.6 - Contact Pathway: Structure and Function II
    Room: 516
    Moderator: Helen Philippou, PhD – University of Leeds.
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:15 – 11:30 ET
    OC 73.6 - Cofactor Regulation of Coagulation Pathways
    Room: 520
    Moderator: James C. Fredenburgh, PhD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Moderator: Rida A. Malik, HBSc – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:15 – 10:30 ET
    OC 70.1 - High molecular kininogen cleavage in cerebral malaria
    Room: 516
    Presenting Author: Alessandro Pinheiro, PhD (he/him/his) – Division of Hematology and Oncology Department of Medicine Case Western Reserve University
    Co-Author: Sadiq Silbak, BS, MS – Department of Pathology, Case Western Reserve University
    Co-Author: Alona Merkulova – Division of Hematology and Oncology Department of Medicine Case Western Reserve University
    Co-Author: Yelenna Skomorovska-Prokvolit – Centre for Global Health and Diseases, Case Western Reserve University
    Co-Author: Keith R. McCrae – Cleveland Clinic Foundation, Cleveland, OH, USA
    Co-Author: David Midem – Chulaimbo Sub-county Hospital
    Co-Author: Sidney Ogolla – Kenya Medical Research Institute
    Co-Author: Arlene Dent – Department of Pediatrics, Centre for Global Health and Diseases, Case Western Reserve University
    Co-Author: Ana Acacia Pinheiro – Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro
    Co-Author: James Kazura – Centre for Global Health and Diseases, Case Western Reserve University
    Co-Author: Alvin Schmaier – Division of Hematology and Oncology Department of Medicine Case Western Reserve University
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:15 – 10:30 ET
    OC 73.1 - Targeted Genetic Disruption of Tissue Factor Pathway Inhibitor (TFPI) Alpha Results in Complete Embryonic Lethality in Mice with Factor V Leiden (FVL)
    Room: 520
    Presenting Author: Amy E. Siebert, MS, PhD (she/her/hers) – Versiti Blood Research Institute
    Co-Author: Susan A. Maroney – Versiti Blood Research Institute
    Co-Author: Nicholas D. Martinez – Versiti Blood Research Institute
    Co-Author: Alan E. Mast, MD, PhD (he/him/his) – Versiti
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:30 – 10:45 ET
    OC 70.2 - The first insight into the spatial structure of human kininogen by cryogenic electron microscopy and computational methods
    Room: 516
    Presenting Author: Michal B. Ponczek, PhD DSc (he/him/his) – University of Lodz, Faculty of Biology and Environmental Protection, Department of General Biochemistry
    Co-Author: Patrycja Dębska – University of Lodz, Faculty of Biology and Environmental Protection, Department of General Biochemistry
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:30 – 10:45 ET
    OC 73.2 - Cryo-EM Structure of Coagulation Factor V short
    Room: 520
    Co-Author: Bassem M. Mohammed, BPharm, PhD (he/him/his) – Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine
    Co-Author: Leslie A. Pelc – Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine
    Co-Author: Michael J. Rau – Washington University, St. Louis
    Presenting Author: Enrico Di Cera, MD – Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:45 – 11:00 ET
    OC 70.3 - Effect of High-Molecular-Weight Kininogen Binding to Factor XI and Prekallikrein on Thrombosis
    Room: 516
    Presenting Author: Bassem M. Mohammed, BPharm, PhD (he/him/his) – Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine
    Co-Author: Mao-fu Sun – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Qiufang Chen – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Priyanka Srivastava, PhD – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Sunil Kumar – Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    10:45 – 11:00 ET
    OC 73.3 - Anticoagulant properties of Factor V activation intermediate (FVai) functioning as synergistic TFPI-cofactor with protein S
    Room: 520
    Presenting Author: Björn Dahlbäck, MD, PhD (he/him/his) – Lund University
    Co-Author: Sinh Tran – Lund University, Dept Translational Medicine
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    11:00 – 11:15 ET
    OC 70.4 - Thrombin activation of the factor XI dimer is a multi-staged process for each subunit
    Room: 516
    Presenting Author: Awital Bar Barroeta, PhD (she/her/hers) – Sanquin, Dept. Molecular Hematology, Amsterdam, The Netherlands
    Co-Author: Pascal Albanese – Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Co-Author: J. Arnoud Marquart – Department of Molecular Hematology, Sanquin, Amsterdam, the Netherlands
    Co-Author: Richard A. Scheltema – Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Co-Author: Joost CM Meijers – Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    11:00 – 11:15 ET
    OC 73.4 - Patients with protein C deficiency have increased NETosis, possibly mediated by reduced levels of circulating activated protein C
    Room: 520
    Co-Author: Julia Oto – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Presenting Author: Raquel Herranz, MSc (she/her/hers) – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Co-Author: Emma Plana – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Angiology and Vascular Surgery Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Fernando Cana – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Co-Author: Maria Castaño – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Co-Author: Isabel Aleman-Cabrera – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Co-Author: Amando Blanquer – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Thrombosis and Haemostasis Unit, Haematology Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Ana Cid – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Thrombosis and Haemostasis Unit, Haematology Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Saturnino Haya – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Thrombosis and Haemostasis Unit, Haematology Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Fernando Ferrando – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Thrombosis and Haemostasis Unit, Haematology Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Santiago Bonanad – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain; Thrombosis and Haemostasis Unit, Haematology Service, La Fe University and Polytechnic Hospital, Valencia, Spain
    Co-Author: Pilar Medina – Hemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe, Valencia, Spain
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    11:15 – 11:30 ET
    OC 70.5 - Coagulation factor XI contributes to the infarct size and inflammation in myocardial ischemia/reperfusion injury
    Room: 516
    Presenting Author: Qi Luo – University Medical Center Mainz, Germany
    Co-Author: Michael Molitor – University Medical Center Mainz, Germany
    Co-Author: Melania Aluia – University Medical Center Mainz, Germany
    Co-Author: Stefanie Finger – University Medical Center Mainz, Germany
    Co-Author: Philip Wenzel, MD (he/him/his) – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz
    Coagulation and Natural Anticoagulants
  • Wednesday, Jun 28th
    11:15 – 11:30 ET
    OC 73.5 - Delineating the Role of Physiologic Ligands on FVIIIa Inactivation
    Room: 520
    Presenting Author: Johnathan J. Morris, PhD (he/him/his) – Children's Hospital of Philadelphia
    Co-Author: Nicole A. Parsons – Perelmen School of Medicine, University of Pennsylvania
    Co-Author: Anna R. Sternberg, PhD – Children's Hospital of Philadelphia
    Co-Author: Noelle C. Novak – Children's Hospital of Philadelphia
    Co-Author: Robert J. Davidson – Children's Hospital of Philadelphia
    Co-Author: Lindsey A. George, MD – University of Pennsylvania
    Coagulation and Natural Anticoagulants