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  • Sunday, Jun 25th
    07:00 – 07:45 ET
    MC 05.1 - Fibrinolysis and Proteolysis in the Brain
    Room: Sherwood Room at the InterContinental Montreal
    Speaker: Robert L. Medcalf, PhD – Monash University
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    11:15 – 11:30 ET
    LB 01.3 - Factor XIII 24-Hour Trajectory Analysis in Severely Injured Patients: Post-Hoc Analysis of the Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Study
    Room: 517
    Presenting Author: Johana C. Gomez Builes, MD, PhD(c) (she/her/hers) – Department of Anesthesia and Pain Medicine, University of Toronto
    Co-Author: Rosane Nisenbaum – MAP Centre for Urban Health Solutions. Applied Health Research Centre.
    Co-Author: Keyvan Karkouti, MD FRCPC MSc – University Health Network; Sinai Health System; Women's College Hospital
    Co-Author: Sunti Barahi – Department of Anesthesia and Pain Medicine, University of Toronto
    Co-Author: Matthew Castello – Department of Surgery, University of Toronto
    Co-Author: Johnny Bai – Department of Anesthesia and Pain Medicine, University of Toronto, Toronto, Canada
    Co-Author: Julian Daza – Department of Surgery, University of Toronto
    Co-Author: Jeannie Callum, MD – Department of Pathology and Molecular Medicine, Kingston Health Sciences Centre, Kingston, Ontario, Canada
    Co-Author: Andrew Baker – Department of Anesthesia and Pain Medicine, St. Michael’s Hospital, Toronto, Canada.
    Co-Author: Michelle Sholzberg, MDCM, FRCPC, MSc., MDCM, FRCPC, MSc – Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, ON, Canada
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    14:45 – 16:00 ET
    OC 28.6 - Factor XIII and Fibrinogen
    Room: 518
    Moderator: Verena Schroeder, PhD – University of Bern
    Moderator: Munira Borhany, MBBS, MCPS, FCPS, FRCP (Edin), FRCPath – Haemophilia Welfare Society, Karachi
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    14:45 – 15:00 ET
    OC 28.1 - Released, but not platelet-associated FXIII-A, is associated with crosslinking activity exposed on the platelet membrane
    Room: 518
    Presenting Author: Yaqiu Sang, PhD – UNC at Chapel Hill
    Co-Author: Fahad S.M. Alshehri – Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen
    Co-Author: Claire S. Whyte, PhD (she/her/hers) – Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen
    Co-Author: Robert H. H. Lee, PhD – University of North Carolina at Chapel Hill
    Co-Author: Abigail Rene R. Ballard – Department of Biochemistry and Biophysics, The University of North Carolina
    Co-Author: Éva Katona, PhD – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen
    Co-Author: Wolfgang Bergmeier, PhD – University of North Carolina at Chapel Hill
    Co-Author: Nicola J. J. Mutch, PhD (she/her/hers) – Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen
    Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    15:00 – 15:15 ET
    OC 28.2 - Neutrophil-derived Factor XIII-A transglutaminase contributes to adipose tissue fibrosis and inflammation in mouse-obesity model
    Room: 518
    Presenting Author: Fatemeh Soltani – Division of Experimental Medicine, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University
    Co-Author: Cedric Duval, PhD (he/him/his) – University of Leeds
    Co-Author: Robert A. S. Ariens, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
    Co-Author: Mari T. Kaartinen – Division of Experimental Medicine, Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    15:30 – 15:45 ET
    OC 28.4 - The flexible alphaC-connector is important for fibrin fibre integrity but not for fibre strength at low strains
    Room: 518
    Presenting Author: Timea Feller, PhD – University of Leeds
    Co-Author: Helen R. McPherson – University of Leeds
    Co-Author: Simon D. A. D. Connell – University of Leeds
    Co-Author: Robert A. S. Ariens, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
    Fibrinolysis and Proteolysis
  • Sunday, Jun 25th
    15:45 – 16:00 ET
    OC 28.5 - Exploring Interdomain Interactions Mediated by the Factor XIII Activation Peptide
    Room: 518
    Presenting Author: Muriel Maurer, PhD – University of Louisville
    Co-Author: Rameesa Syed Mohammed – University of Louisville
    Co-Author: Lianay Gutierrez Luque – University of Louisville
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    07:00 – 07:45 ET
    MC 20.1 - The Role of Tranexamic Acid in Prevention and Management of Bleeding
    Room: Fraser Room at the InterContinental Montreal
    Speaker: Michelle Sholzberg, MDCM, FRCPC, MSc., MDCM, FRCPC, MSc – Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, ON, Canada
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    08:00 – 09:15 ET
    SOA 08.4 - Cell-Dependent Fibrinolysis
    Room: 511
    Moderator: Matthew J. Flick, PhD – University of North Carolina at Chapel Hill
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    08:00 – 08:25 ET
    SOA 08.1 - Fibrin Is a Critical Regulator of Oral Mucosal Homeostasis
    Room: 511
    Speaker: Lakmali M. Silva, PhD (she/her/hers) – National Institutes of Health
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    08:25 – 08:50 ET
    SOA 08.2 - Fibrinogen and Fibrinolysis and Aortic Macrophages
    Room: 511
    Speaker: Luisa Iruela-Arispe, PhD – Northwestern University Feinberg School of Medicine
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    08:50 – 09:15 ET
    SOA 08.3 - TAFI and Platelet-Mediated Regulation of Fibrinolysis
    Room: 511
    Speaker: Paul Y. Kim, PhD (he/him/his) – Department of Medicine, McMaster University
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    10:45 – 12:00 ET
    OC 37.6 - Fibrinolysis and Proteolysis
    Room: 524
    Moderator: Robert L. Medcalf, PhD – Monash University
    Moderator: Lauren Poole, PhD – Rutgers University Robert Wood Johnson Medical School, Department of Pharmacology
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    10:45 – 11:00 ET
    OC 37.1 - Hypoalbuminemia increases clot fibrin network density and impairs fibrinolysis during glomerular proteinuria
    Room: 524
    Presenting Author: Amanda P. Waller, MSc, PhD – The Research Institute at Nationwide Children's Hospital
    Co-Author: Katelyn J. Wolfgang – The Research Institute at Nationwide Children's Hospital
    Co-Author: Zachary Stevenson – The Research Institute at Nationwide Children's Hospital
    Co-Author: Bryce A. Kerlin, MD, FAAP – Division of Hematology/Oncology/BMT, Nationwide Children's Hospital
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    11:00 – 11:15 ET
    OC 37.2 - Activated PC enhances the renal tubular regeneration in diabetic kidney disease
    Room: 524
    Presenting Author: Ahmed Elwakiel, M.Sc. – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.
    Co-Author: Dheerendra Gupta, Msc – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany.
    Co-Author: Kunal Singh – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Sameen Fatima, MPhil – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Saira Ambreen – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Anubhuti Gupta – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Shrey Kohli, PhD – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Khurrum Shahzad – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Co-Author: Berend Isermann, PhD MD (he/him/his) – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    11:15 – 11:30 ET
    OC 37.3 - Increased concentrations of lipoprotein (a) as a factor enhancing hypofibrinolysis in patients with severe aortic stenosis
    Room: 524
    Presenting Author: Magdalena Kopytek, MS (she/her/hers) – Jagiellonian University Medical College, The John Paul II Hospital
    Co-Author: Michał Ząbczyk, PhD – Jagiellonian University Medical College
    Co-Author: Anetta Undas, MD PhD – Jagiellonian University Medical College
    Co-Author: Joanna Natorska – Jagiellonian University Medical College
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    11:30 – 11:45 ET
    OC 37.4 - Plasminogen retention is attenuated in thrombi from Plg-RKT deficient mice
    Room: 524
    Presenting Author: Claire S. Whyte, PhD (she/her/hers) – Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen
    Co-Author: Dean Kavanagh – University of Birmingham
    Co-Author: Ausra S. Lionikiene – University of Aberdeen
    Co-Author: Steve Watson – University of Birmingham
    Co-Author: Robert J. Parmer – University of California San Diego, and Veterans Administration San Diego Healthcare System
    Co-Author: Lindsey A. Miles – Department of Cell Biology, The Scripps Research Institute
    Co-Author: Nicola J. J. Mutch, PhD (she/her/hers) – Aberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen
    Fibrinolysis and Proteolysis
  • Monday, Jun 26th
    11:45 – 12:00 ET
    OC 37.5 - Vaccine-induced immune thrombotic thrombocytopenia produces a marked hyperfibrinolytic state and generates a plasma cofactor that potentiates tPA-mediated plasminogen activation
    Room: 524
    Presenting Author: Charithani Keragala, MBBS (Hons), FRACP, FRCPA (she/her/hers) – Monash University
    Co-Author: James D. McFadyen – Department of Haematology, Alfred Health, Melbourne, VIC, Australia
    Co-Author: Heidi Ho – Monash University
    Co-Author: Fiona McCutcheon – Monash University
    Co-Author: Zikou Liu – Monash University
    Co-Author: Hannah Stevens – Monash University
    Co-Author: Paul Monagle, MD – Haematology Research, Murdoch Children's Research Institute
    Co-Author: Sanjeev Chunilal – Monash Health
    Co-Author: Robert L. Medcalf, PhD – Monash University
    Co-Author: Huyen Tran – Australian Centre for Blood Diseases, Monash University
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    10:45 – 12:00 ET
    OC 53.6 - Fibrinolysis and Novel Strategies
    Room: 520
    Moderator: Ze Zheng, PhD – Medical College of Wisconsin, Versiti Blood Research Institute
    Moderator: Cedric Duval, PhD (he/him/his) – University of Leeds
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    10:45 – 11:00 ET
    OC 53.1 - Magnetically Powered Microwheels Enhance Thrombolysis in a Murine Model of Ischemic Stroke
    Room: 520
    Presenting Author: Matthew J. Osmond, PhD (he/him/his) – University of Colorado - Anschutz Medical Campus and Colorado School of Mines
    Co-Author: Dave W.M. Marr – Colorado School of Mines
    Co-Author: Keith B. Neeves, PhD – University of Colorado Anschutz Medical Campus
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    11:00 – 11:15 ET
    OC 53.2 - Does Plasminogen Replenishment Correct Recovery from Fibrinolysis Resistance Following Liver Transplantation?
    Room: 520
    Presenting Author: Hunter B. Moore, MD, PhD (he/him/his) – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: Ivan E. Rodriguez – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: Wells B. LaRiviere – University of Colorado
    Co-Author: Kristen Brown – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: Kyndall Hadley – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: James Pomposelli – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: Elizabeth Pomfret – Division of Transplant Surgery, University of Colorado School of Medicine
    Co-Author: Trevor Nydam – Division of Transplant Surgery, University of Colorado School of Medicine
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    11:15 – 11:30 ET
    OC 53.3 - Direct Delivery of Plasmin using Clot-anchoring Thrombin-responsive Nanoparticles for Targeted Fibrinolytic Therapy
    Room: 520
    Presenting Author: Anirban Sen Gupta, PhD (he/him/his) – Case Western Reserve University
    Co-Author: Michael Sun – Department of Biomedical Engineering, Case Western Reserve University
    Co-Author: Maxine Hao Hao Pontius – Department of Pediatrics, University of Michigan Medical School
    Co-Author: Stephanie Yang – Department of Biomedical Engineering, Case Western Reserve University
    Co-Author: Tejal Pendekanti – Department of Biomedical Engineering, Case Western Resrve University
    Co-Author: Shruti Raghunathan – Department of Biomedical Engineering, Case Western Reserve University
    Co-Author: Jordan A. Shavit, MD, PhD (he/him/his) – Department of Pediatrics and Department of Human Genetics, University of Michigan Medical School
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    11:30 – 11:45 ET
    OC 53.4 - An siRNA gene therapy to modulate circulating plasminogen activator inhibitor 1
    Room: 520
    Presenting Author: Francesca Ferraresso, BSc – University of British Columbia
    Co-Author: Woosuk Steve Hur, PhD – University of North Carolina at Chapel Hill
    Co-Author: Lih Jiin Juang – UBC
    Co-Author: Amy W. Strilchuk – UBC
    Co-Author: Matthew J. Flick, PhD – University of North Carolina at Chapel Hill
    Co-Author: Christian Kastrup, PhD – Versiti Blood Research Institute
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    11:45 – 12:00 ET
    OC 53.5 - Clinical outcomes in patients with acute pulmonary embolism undergoing ultrasound-assisted catheter-directed thrombolysis
    Room: 520
    Presenting Author: Dominik F. Draxler, MD PhD MBA (he/him/his) – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Judith Johannes – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Elisabeth Turovskij – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Caglayan Demirel – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Dierik Heg – CTU Bern, University of Bern, Switzerland
    Co-Author: Stephan Dobner – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Stephan Windecker – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Co-Author: Stefan Stortecky – Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1193 - Acute myocardial infarction thrombi show fibrin film that increases with ischaemia duration
    Room: Exhibition
    Presenting Author: Cedric Duval, PhD (he/him/his) – University of Leeds
    Co-Author: Helen R. McPherson – University of Leeds
    Co-Author: John Greenwood – University of Leeds
    Co-Author: Robert A. S. Ariens, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1195 - Biochemical and structural regulation of the enzymatic degradation of blood clots
    Room: Exhibition
    Presenting Author: Rebecca Risman – Rutgers University
    Co-Author: Victoria Percoco – Rutgers University
    Co-Author: Mitali Shroff – Rutgers University
    Co-Author: Brittany Bannish – University of Central Oklahoma
    Co-Author: Valerie Tutwiler, PhD – Rutgers-State University of New Jersey
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1196 - In vitro comparisons of two fibrinogen concentrates on fibrin clot properties in dysfibrinogenemia
    Room: Exhibition
    Presenting Author: Rita Marchi – UNIGE
    Co-Author: Stéphane Dural – UNIGE
    Co-Author: Tomas Simurda, MD, PhD. – National Centre of Hemostasis and Thrombosis, Department of Hematology and Transfusiology, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin and University Hospital in Martin, Slovakia
    Co-Author: Marguerite Neerman-Arbez – Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Co-Author: Alessandro Casini, MD – Division of Angiology and Hemostasis, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1197 - Neutrophil serine proteases cleave fibrinogen to alter fibrin clot structure
    Room: Exhibition
    Presenting Author: Stephanie A. Smith, DVM (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Patrick Suess, PhD – University of Michigan Medical School
    Co-Author: James H. Morrissey, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1198 - Retrospective Genotypic Data Analysis of Patients with Suspected Hereditary Fibrinogen Deficiency
    Room: Exhibition
    Presenting Author: Vytautas Ivaskevicius, MD, PhD – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Co-Author: Martynas Vitkus – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Co-Author: Arijit Biswas, PD Dr (Biol) – Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn
    Co-Author: Anna Pavlova – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Co-Author: Johannes Oldenburg, MD (he/him/his) – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine, Bonn, Germany
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1200 - Evaluation of the association of factor XIII at hospital arrival and outcomes in a cohort of severely injured patients
    Room: Exhibition
    Presenting Author: Johana C. Gomez Builes, MD, PhD(c) (she/her/hers) – Department of Anesthesia and Pain Medicine, University of Toronto
    Co-Author: Andrew Baker – Department of Anesthesia and Pain Medicine, St. Michael’s Hospital, Toronto, Canada.
    Co-Author: Jeannie Callum, MD – Department of Pathology and Molecular Medicine, Kingston Health Sciences Centre, Kingston, Ontario, Canada
    Co-Author: Sunti Barahi – Department of Anesthesia and Pain Medicine, University of Toronto
    Co-Author: Johnny Bai – Department of Anesthesia and Pain Medicine, University of Toronto, Toronto, Canada
    Co-Author: Keyvan Karkouti, MD FRCPC MSc – University Health Network; Sinai Health System; Women's College Hospital
    Co-Author: Rosane Nisenbaum – MAP Centre for Urban Health Solutions. Applied Health Research Centre.
    Co-Author: Michelle Sholzberg, MDCM, FRCPC, MSc., MDCM, FRCPC, MSc – Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, ON, Canada
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1201 - Update on the proposed standardized method for scanning electron microscopy analysis of fibrin clots
    Room: Exhibition
    Presenting Author: Marlien Pieters, PhD (she/her/hers) – North-West University
    Co-Author: Zelda de Lange-Loots, PhD Nutrition (she/her/hers) – North-West University
    Co-Author: Stephen R. Baker, PhD – Wake Forest University
    Co-Author: Can Cai – Wake Forest University
    Co-Author: Albe Swanepoel – North-West University
    Co-Author: Rustem I. Litvinov, MD, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Chandrasekaran Nagaswami – university of Pennsylvania
    Co-Author: John W. Weisel, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Martin Guthold, PhD (he/him/his) – Wake Forest University
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1202 - Fibrinogen concentration and plasma clot properties as predictors of cardiovascular disease mortality in Black South Africans
    Room: Exhibition
    Presenting Author: Marlien Pieters, PhD (she/her/hers) – North-West University
    Co-Author: Dina Jankowitz – North-West University
    Co-Author: Zelda de Lange-Loots, PhD Nutrition (she/her/hers) – North-West University
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1203 - The influence of human immunodeficiency virus infection and antiretroviral therapy on plasma clot properties in a group of Black South African women
    Room: Exhibition
    Presenting Author: Zelda de Lange-Loots, PhD Nutrition (she/her/hers) – North-West University
    Co-Author: Marlien Pieters, PhD (she/her/hers) – North-West University
    Co-Author: Shams Bakali – North-West University
    Co-Author: Anine Jordaan – North-West University
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1204 - Synergistic role in accelerating clot formation and fibrin polymerisation of cancer cells and platelets: a thromboelastometric study
    Room: Exhibition
    Co-Author: Elisabeth Mbemba – Sorbonne Université INSERM UMR S938 Paris France
    Co-Author: Patrick Van Dreden, PhD – Clinical Research Department, Diagnostica Stago
    Presenting Author: Grigorios Gerotziafas – Research Group "Cancer - Hemostasis - Angiogenesis" Thrombosis Center
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1205 - In vitro analysis of plasma clots with 0.7 to 10.4 g/L fibrinogen concentration by turbidity, permeation and laser scanning electron microscopy
    Room: Exhibition
    Presenting Author: Rita Marchi – UNIGE
    Co-Author: Nicolas Liaudet – UNIGE
    Co-Author: Marguerite Neerman-Arbez – Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1206 - Plasmin generation is impaired in patients with bleeding disorders of unknown cause
    Room: Exhibition
    Presenting Author: Dino Mehic, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Stéphanie E. Reitsma, PhD – Department of Pathology and Laboratory Medicine, UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Co-Author: Helmuth Haslacher – Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
    Co-Author: Maximilian Köller – Department of Pathology, Medical University of Vienna, Vienna, Austria
    Co-Author: Bas de Laat, MD, PhD – Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands
    Co-Author: Cihan Ay, MD (he/him/his) – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Ingrid Pabinger, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill
    Co-Author: Johanna Gebhart, MD, PhD (she/her/hers) – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1208 - Thrombin Activatable Fibrinolysis Inhibitor Dependent Effects on Whole Blood Clot Formation and Lysis Dynamics Across the Peripartum Period
    Room: Exhibition
    Presenting Author: Matthew Gissel – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Ira Bernstein, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Kelley McLean, MD – Department of Obstetrics, Gynecology & Reproductive Sciences, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Maria Cristina Bravo, PhD, PhD (she/her/hers) – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Co-Author: Thomas Orfeo, PhD – Department of Biochemistry, The Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT 05405, USA
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1209 - Thrombo-inflammatory and Fibrinolytic Deficit Biomarkers and their Relationship with Circulating Glycosaminoglycans in End-Stage Renal Disease Patients
    Room: Exhibition
    Co-Author: Madeline Allen, BS – Loyola University Medical Center
    Co-Author: Vinod Bansal – Loyola University Medical Center
    Co-Author: Fakiha Siddiqui, PhD Candidate – Department of Pathology and Laboratory Medicine, Cardiovascular Research Institute, Loyola University Chicago, Health Sciences Division, Maywood, IL, USA.
    Co-Author: Debra Hoppensteadt – Loyola University Chicago
    Presenting Author: Emily Krupa, BS – Loyola University Chicago
    Co-Author: Bulent Kantarcioglu, MD – Loyola University Chicago
    Co-Author: Jawed Fareed, n/a – Loyola University Medical Center
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1210 - Incorporation of α2-Plasmin Inhibitor into Plasma Clots of Patients with Venous Thrombosis
    Room: Exhibition
    Co-Author: Éva Katona, PhD – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen
    Co-Author: Barbara Baráth, PhD – Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Co-Author: Réka Gindele – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Co-Author: Tünde Miklós – Division of Clinical Laboratory Sience, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen
    Presenting Author: Zsuzsanna Bereczky, MD, PhD (she/her/hers) – Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1211 - Individual determination of the components of the fibrinolytic system in platelet-depleted plasma and derived euglobulin fraction
    Room: Exhibition
    Presenting Author: Marion A. Bareille, PharmD, MSc (she/her/hers) – Université Catholique de Louvain, CHU UCL Namur, Haematology Laboratory, Yvoir, Belgium
    Co-Author: Thomas Lecompte – Université de Lorraine, Nancy, France
    Co-Author: François Mullier – Université catholique de Louvain, CHU UCL Namur, NTHC, NARILIS, Hematology Laboratory, Namur, Belgium
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1212 - Effect of PAI-1 on clot structure and fibrinolysis
    Room: Exhibition
    Presenting Author: Rebecca Risman – Rutgers University
    Co-Author: Hajer Ali – The College of New Jersey
    Co-Author: Valerie Tutwiler, PhD – Rutgers-State University of New Jersey
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1213 - The Development of a Mini-scale Euglobulin Clot Lysis Assay
    Room: Exhibition
    Presenting Author: Steven Bruzek, MS, MB(ASCP) – Institute for Clinical and Translational Research, Johns Hopkins All Children's Hospital, St. Petersburg, USA
    Co-Author: Marisol Betensky, MD, MPH – Institute for Clinical and Translational Research, Johns Hopkins All Children's Hospital, St. Petersburg, USA
    Co-Author: Neil A. Goldenberg, MD, PhD (he/him/his) – Johns Hopkins All Children's Institute for Clinical and Translational Research, Johns Hopkins University, USA
    Co-Author: Vera Ignjatovic, PhD (she/her/hers) – Institute for Clinical and Translational Research, Johns Hopkins All Children's Hospital, St. Petersburg, USA
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1214 - Characterization of dynamic changes to fibrinolysis in porcine model of cardiac arrest
    Room: Exhibition
    Presenting Author: Hena Noorzada, HBsc – Department of Medicine, McMaster University, Hamilton, Canada
    Co-Author: Rohit Mohindra – Li Ka Shing Research Institute, St Michael's Hospital, University of Toronto
    Co-Author: Danielle Bince – Li Ka Shing Research Institute, St Michael's Hospital, University of Toronto
    Co-Author: Vanessa A. sabourin – Thrombosis and Atherosclerosis Research Institute, Hamilton Canada
    Co-Author: Calvin H. Yeh – Department of Medicine, McMaster University
    Co-Author: Steve Lin – Li Ka Shing Research Institute, St Michael's Hospital, University of Toronto
    Co-Author: Paul Y. Kim, PhD (he/him/his) – Department of Medicine, McMaster University
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1217 - The contribution of plasmin(ogen) receptors to neuroinflammation in a murine model of MS.
    Room: Exhibition
    Presenting Author: Jeremy A. Thompson – Cincinnati Children's Hospital Medical Center
    Co-Author: Molly W. Shaw – Cincinnati Children's Hospital Medical Center
    Co-Author: Robert J. Parmer – Department of Medicine, University of California San Diego
    Co-Author: Lindsey A. Miles – Department of Cell Biology, The Scripps Research Institute
    Co-Author: Eric S. Mullins, MD – Division of Hematology, Cincinnati Children's Hospital Medical Center
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1218 - Aptamer Inhibitor of Von Willebrand Factor Induces Thrombolysis and Improves Vascular Patency Upon Immediate and Delayed Treatment in a Microfluidic Model of Stroke
    Room: Exhibition
    Presenting Author: Emily P. Mihalko, PhD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Rassam M.G. Rassam – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Shahid Nimjee – Department of Neurological Surgery, The Ohio State University Medical Center, Columbus, OH, USA
    Co-Author: Susan M. Shea, MSME, PhD (she/her/hers) – Trauma and Transfusion Medicine Research Center, Department of Surgery and Department of Bioengineering, University of Pittsburgh
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1219 - Structure-function studies on the serine protease domain of Factor VII activating protease (FSAP) to characterize its interaction with substrates and inhibitors.
    Room: Exhibition
    Co-Author: Sai Priya Sarma Kandanur – University of Oslo
    Co-Author: Bjørn Dalhus – University of Oslo
    Presenting Author: Jonas Emsley, Phd – Nottingham Biodiscovery Institute, School of Pharmacy
    Co-Author: Sandip M. M. Kanse – University of Oslo
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1220 - DNase-1 overcomes thrombolytic rt-PA resistance of platelet-rich ischemic stroke thrombi
    Room: Exhibition
    Presenting Author: Sarah Vandelanotte, MA – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Co-Author: Olivier Francois – Department of Medical Imaging, AZ Groeninge, Kortrijk, Belgium
    Co-Author: Senna Staessens – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk
    Co-Author: Linda Desender – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk
    Co-Author: Alexander Vanhoorne – Department of Medical Imaging, AZ Groeninge, Kortrijk, Belgium
    Co-Author: Claudia Tersteeg – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Co-Author: Karen Vanhoorelbeke, PhD – KU Leuven
    Co-Author: Peter Vanacker – Department of Neurology, AZ Groeninge, Kortrijk, Belgium / Neurovascular Center and Stroke Unit Antwerp, Antwerp University Hospital, Antwerp, Belgium. / Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
    Co-Author: Tommy Andersson – Departments of Neuroradiology, Karolinska University Hospital, and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Co-Author: Simon F. De Meyer – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1221 - Prospective study comparing Point-of-Care viscoelastic testing and standard laboratory testing for the prediction of bleeding complications in patients after systemic thrombolysis therapy
    Room: Exhibition
    Presenting Author: Martin Mirus (he/him/his) – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Lars Heubner, MD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Ralph Schneider – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Internal Medicine, Dresden, Saxony, Germany
    Co-Author: Volker Puetz – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Neurology, Neurovascular Center, Dresden, Saxony, Germany
    Co-Author: Simone Bonin – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Internal Medicine, Dresden, Saxony, Germany
    Co-Author: Andreas Güldner – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Thea Koch – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Co-Author: Peter Spieth – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Department of Anesthesiology and Intensive Care Medicine, Dresden, Saxony, Germany
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1222 - ROTEM-Identified Hyperfibrinolysis does not Correlate with Poor Outcomes in Large Vessel Occlusion Stroke
    Room: Exhibition
    Presenting Author: Susan M. Shea, MSME, PhD (she/her/hers) – Trauma and Transfusion Medicine Research Center, Department of Surgery and Department of Bioengineering, University of Pittsburgh
    Co-Author: Amanda Zakeri – OSUMC
    Co-Author: Jessica Zakeri – OSUMC
    Co-Author: Patrick Youssef – OSUMC
    Co-Author: Ciaran Powers – OSUMC
    Co-Author: Rassam M.G. Rassam – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Emily P. Mihalko, PhD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Shahid Nimjee – Department of Neurological Surgery, The Ohio State University Medical Center, Columbus, OH, USA
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1223 - EkoSonic Endovascular System promotes thrombolysis by altering fibrin fibre thickness
    Room: Exhibition
    Presenting Author: Cedric Duval, PhD (he/him/his) – University of Leeds
    Co-Author: Robert A. S. Ariens, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
    Fibrinolysis and Proteolysis
  • Tuesday, Jun 27th
    18:30 – 19:30 ET
    PB1224 - Cell-Lysis (Lysozyme) Activity in Japanese Fermented Food-Natto
    Room: Exhibition
    Presenting Author: Hiroyuki Sumi, PhD – Kurashiki University of Science and the Arts
    Co-Author: Masatoshi Imai – Kurashiki University of Science and the Arts
    Co-Author: Tadashi Mitsuo – Mitsuo Clinic
    Co-Author: Chieko Yatagai – Kurashiki University of Science and the Arts
    Fibrinolysis and Proteolysis
  • Wednesday, Jun 28th
    08:30 – 09:45 ET
    SOA 23.4 - Fibrinolysis in Diseases
    Room: 710A
    Moderator: James P. Luyendyk, PhD – Michigan State University, College of Veterinary Medicine, Department of Pathobiology and Diagnostic Investigation
    Moderator: Woosuk Steve Hur, PhD – University of North Carolina at Chapel Hill
    Fibrinolysis and Proteolysis
  • Wednesday, Jun 28th
    08:30 – 08:55 ET
    SOA 23.1 - Connecting Fibrinolysis and Dyslipidemia
    Room: 710A
    Speaker: Ze Zheng, PhD – Medical College of Wisconsin, Versiti Blood Research Institute
    Fibrinolysis and Proteolysis
  • Wednesday, Jun 28th
    08:55 – 09:20 ET
    SOA 23.2 - Fibrinolysis in Patients with Liver Disease
    Room: 710A
    Speaker: Ton Lisman, PhD – UMCG
    Fibrinolysis and Proteolysis
  • Wednesday, Jun 28th
    09:20 – 09:45 ET
    SOA 23.3 - RNA Therapeutics to Control Fibrinolysis
    Room: 710A
    Speaker: Christian Kastrup, PhD – Versiti Blood Research Institute
    Fibrinolysis and Proteolysis