Skip to main content



  • Sunday, Jun 25th
    08:00 – 09:15 ET
    SOA 04.4 - Platelets and Cancer
    Room: 710B
    Moderator: Elisabeth M. Battinelli, MD PhD (she/her/hers) – Associate Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
    Moderator: Georges JOURDI, PharmD, PhD (he/him/his) – Université Paris Cité and APHP. Nord
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    08:00 – 08:25 ET
    SOA 04.1 - Platelet-Derived PDGFB in Tumor Vessel Integrity and Metastasis
    Room: 710B
    Speaker: Anna-Karin Olsson, PhD (she/her/hers) – Uppsala University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    08:25 – 08:50 ET
    SOA 04.2 - Targeting Platelets for Metastasis Prevention
    Room: 710B
    Speaker: Serena Lucotti, PhD (she/her/hers) – Weill Cornell Medicine
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    08:50 – 09:15 ET
    SOA 04.3 - Platelets and Megakaryocytes in Cancer
    Room: 710B
    Speaker: Emma C. Josefsson, PhD (she/her/hers) – Sahlgrenska University Hospital
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    10:45 – 12:00 ET
    OC 18.6 - Modulators of Platelet Function
    Room: 518
    Moderator: Marie Hollenhorst, MD PhD (she/her/hers) – Brigham and Women's Hospital, Harvard Medical School
    Moderator: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    10:45 – 11:00 ET
    OC 18.1 - The role of Mitochondrial Calcium Uniporter in platelet function
    Room: 518
    Presenting Author: Abigail Ajanel, MS (she/her/hers) – University of Utah
    Co-Author: Frederik Denorme, PhD (he/him/his) – University of Utah
    Co-Author: Irina Portier, PhD – University of Utah
    Co-Author: Yasuhiro Kosaka – University of Utah Molecular Medicine Program
    Co-Author: Robert A. Campbell, PhD – University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    11:00 – 11:15 ET
    OC 18.2 - A signature of platelet reactivity in complete blood count scattergrams identifies genes with thrombotic disease associations
    Room: 518
    Co-Author: Hippolyte Verdier – Institut Pasteur, CNRS
    Co-Author: Kate Downes, PhD – East Genomics, Cambridge Genomics Laboratory
    Co-Author: William Astle – University of Cambridge
    Presenting Author: Ernest Turro, PhD – Icahn School of Medicine at Mount Sinai
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    11:15 – 11:30 ET
    OC 18.3 - Platelet mitochondrial bioenergetics is critical for clot contraction, hemostasis and thrombosis
    Room: 518
    Presenting Author: Kanakanagavalli Shravani Prakhya, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Hemendra Vekaria – University of Kentucky
    Co-Author: Joshua Lykins – University of Kentucky
    Co-Author: Daniëlle M. Coenen, MSc, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Smita Joshi, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Patrick Sullivan – University of Kentucky
    Co-Author: Sidney W. Whiteheart – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    11:30 – 11:45 ET
    OC 18.4 - Actin Bundling Protein L-Plastin Regulates Platelet Spreading and Thrombosis
    Room: 518
    Co-Author: Li GUO, MD PhD (she/her/hers) – 1. Bloodworks Research Institute; 2. Hematology Division University of Washington; 3. University of Utah
    Presenting Author: Raymond Adili – Bloodworks Research Institute
    Co-Author: Shancy Jacob – Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA
    Co-Author: Bhanu Kanth Manne – University of Utah
    Co-Author: Seema Bhatlekar – University of Utah
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    11:45 – 12:00 ET
    OC 18.5 - Alpha-dystroglycan supports platelet aggregation and hemostasis/thrombosis via binding to GPIbα
    Room: 518
    Presenting Author: Viktor Prifti – Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
    Co-Author: Reid Gallant – Department of Medicine, University of Toronto, Toronto, Canada
    Co-Author: Aron A. Shoara, PhD – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada
    Co-Author: Kanwal Singh – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada
    Co-Author: Xi Lei – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada
    Co-Author: Yiming Wang – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada
    Co-Author: Heyu Ni, MD, PhD – Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    14:45 – 16:00 ET
    OC 27.6 - Megakaryocyte Biology
    Room: 524
    Moderator: Genevieve Pepin, PhD, MBA – Université Du Québec à Trois-RIvières
    Moderator: Robert A. Campbell, PhD – University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    14:45 – 15:00 ET
    OC 27.1 - Kupffer cells are required for platelet-mediated hepatocellular TPO generation
    Room: 524
    Presenting Author: Danielle Karakas (she/her/hers) – Department of Laboratory Medicine and Pathobiology, University of Toronto
    Co-Author: June Li – Department of Laboratory Medicine and Pathobiology, University of Toronto
    Co-Author: Wenjing Ma – Keenan Research Centre, St. Michael's Hospital
    Co-Author: Mina Masoud – Department of Laboratory Medicine and Pathobiology, University of Toronto
    Co-Author: Chuanbin Shen – Keenan Research Centre, St. Michael's Hospital
    Co-Author: Sonya MacParland – University of Toronto
    Co-Author: Walter HA Kahr, MD, PhD (he/him/his) – Professor Departments of Paediatrics & Biochemistry, University of Toronto
    Co-Author: Heyu Ni, MD, PhD – Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    15:00 – 15:15 ET
    OC 27.2 - Mechanistic studies of runt-related transcription factor-1 (RUNX1)-deficient megakaryopoiesis and its correction by RepSox (RS), a TGFβ-receptor-1 inhibitor
    Room: 524
    Presenting Author: Kiwon Lee, PhD (he/him/his) – Division of Hematology, Children's Hospital of Philadelphia
    Co-Author: Michael Gonzalez – The Center for Cytokine Storm Treatment and Laboratory, University of Pennsylvania
    Co-Author: Mortimer Poncz – Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    15:15 – 15:30 ET
    OC 27.3 - Single-cell transcriptomics reveal critical roles of G6b-B in regulating the megakaryocyte maturation
    Room: 524
    Presenting Author: Maximilian Englert, MSc – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Co-Author: Zoltan Nagy – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    15:30 – 15:45 ET
    OC 27.4 - ZFPM2 regulates megakaryocyte proliferation, differentiation and granulogenesis and influences thrombotic risk
    Room: 524
    Presenting Author: Kate L. Burley, MBChB (she/her/hers) – University of Bristol
    Co-Author: Amber Knapp-Wilson – University of Bristol
    Co-Author: Sarah Westbury – University of Bristol
    Co-Author: Parsa Akbari – Regeneron Pharmaceuticals Inc
    Co-Author: Luca Stefanucci – University of Cambridge
    Co-Author: William Astle – University of Cambridge
    Co-Author: Mattia Frontini – University of Exeter
    Co-Author: Andrew Mumford – University of Bristol
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    15:45 – 16:00 ET
    OC 27.5 - Single-cell RNA-Seq reveals age-dependent Mfsd2b expression in megakaryocyte progenitors that regulates thrombosis
    Room: 524
    Presenting Author: Seyed Soheil Saeedi Saravi, PharmD, PhD (he/him/his) – Center for Translational and Experimental Cardiology (CTEC), University Hospital Zurich, University of Zurich
    Co-Author: Meret Allemann – Center for Molecular Cardiology, University of Zurich
    Co-Author: Pratintip Lee – Center for Molecular Cardiology, University of Zurich
    Co-Author: Wenfei Sun – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Tongtong Wang – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Hua Dong – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Christian Wolfrum – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Jürg Hans Beer – Department of Internal Medicine, Cantonal Hospital Baden
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0368 - Development and First Human Transfusion of Allogeneic iPSC-Derived Platelet Product (MEG-002)
    Room: Exhibition
    Presenting Author: Kazumasa Takao, PhD (he/him/his) – Megakaryon Corporation
    Co-Author: Hidenori Hirose – Megakaryon Corporation
    Co-Author: Hiromichi Konno – Megakaryon Corporation
    Co-Author: Naoshi Sugimoto – Center for iPS Cell Research and Application, Kyoto University
    Co-Author: Junya Kanda – Department of Hematology, Kyoto University Hospital
    Co-Author: Yuya Sato – Megakaryon Corporation
    Co-Author: Yasuko Hazama – Megakaryon Corporation
    Co-Author: Michiko Ueda – Megakaryon Corporation
    Co-Author: Yamato Haraguchi – Megakaryon Corporation
    Co-Author: Mizue Suzuki – Megakaryon Corporation
    Co-Author: Junko Tomizuka – Megakaryon Corporation
    Co-Author: Masayuki Nogawa – Keio University School of Medicine
    Co-Author: Naohide Watanabe – Keio University School of Medicine
    Co-Author: Akira Sawaguchi – Department of Anatomy, Faculty of Medicine, University of Miyazaki
    Co-Author: Akifumi Takaori-Kondo – Department of Hematology, Kyoto University Hospital
    Co-Author: Yoshihiro Kumagae – Megakaryon Corporation
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0369 - New insights into the formation of platelets (thrombopoiesis) from infused megakaryocytes (Mks) into mice
    Room: Exhibition
    Presenting Author: Hyunjun Kim, MS – Division of Hematology, Children's Hospital of Philadelphia
    Co-Author: Deborah L. French – Department of Pathology, Perelman School of Medicine at the University of Pennsylvania
    Co-Author: Mortimer Poncz – Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0373 - Increased megakaryopoiesis and thrombopoiesis induced by plasma from Myelofibrosis and Essential Thrombocythemia patients
    Room: Exhibition
    Co-Author: Danila B. Yañuk, N/A – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Rosana F. Marta – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Adela S. Cellucci, PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Geraldine De Luca, PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Ailen D. Discianni – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, UBA
    Presenting Author: Paula G. Heller, MD PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Nora P. Goette – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, UBA
    Co-Author: Paola R. Lev – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0374 - JAM-A regulates zipper-like structures that are essential for maintaining the integrity of megakaryocytes.
    Room: Exhibition
    Presenting Author: Claire MASSON, PhD – UMR_S 1255 EFS INSERM
    Co-Author: Olivier Destaing – INSERM 1209, CNRS UMR5309, Institute for Advanced Biosciences
    Co-Author: Maxime Lehmann – UMR_S 1255 EFS INSERM
    Co-Author: Anita Eckly – UMR_S 1255 EFS INSERM
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0375 - Changes in platelet size induced by treatment in patients with Myeloproliferative Neoplasms. Cytoskeletal study during platelet production.
    Room: Exhibition
    Presenting Author: Adela S. Cellucci, PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Paola R. Lev – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Danila B. Yañuk, N/A – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Nora P. Goette – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, UBA
    Co-Author: Ana C. Glembotsky – Instituto de Investigaciones Médicas “Alfredo Lanari”, Departamento de Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Geraldine De Luca, PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Maria Lira – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento de Apoptosis y Biologia Molecular, IDIM UBA-CONICET
    Co-Author: Constanza Baroni Pietto – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICETIDIM UBA CONICET
    Co-Author: Paula G. Heller, MD PhD – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Co-Author: Rosana F. Marta – Instituto de Investigaciones Médicas "Alfredo Lanari", Departamento Hematología Investigación, IDIM UBA-CONICET
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0376 - Vacuolar-type ATPase dependent acidification of megakaryocyte and platelet α-granules maintains packaging of VWF
    Room: Exhibition
    Presenting Author: Walter HA Kahr, MD, PhD (he/him/his) – Professor Departments of Paediatrics & Biochemistry, University of Toronto
    Co-Author: Chien-Yi Lu – University of Toronto
    Co-Author: Jing Ze Wu – University of Toronto
    Co-Author: Fred G. Pluthero – SickKids Research Institute
    Co-Author: Ling Li – SickKids Research Institute
    Co-Author: Richard JY Liu – University of Toronto
    Co-Author: Helen HY Yao – University of Toronto
    Co-Author: Sergio Grinstein – University of Toronto
    Co-Author: Spencer Freeman – University of Toronto
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0377 - Analysis of hepatic TPO production after myocardial infarction and partial hepatectomy
    Room: Exhibition
    Presenting Author: Niloofar Salehzadeh, MS (she/her/hers) – Institute of experimental vascular medicine
    Co-Author: Friedrich WB Reusswig – Department of Vascular- and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany
    Co-Author: Sevgi C. Cengiz, PhD (she/her/hers) – Institute of Experimantal Vascular Medicine
    Co-Author: Kristina Vogel – Institute of Biochemistry and Molecular Biology II
    Co-Author: Jürgen Scheller – Institute of Biochemistry and Molecular Biology II
    Co-Author: Margitta Elvers – Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany.
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0378 - DNA Damage Accumulation in Polyploid Megakaryocytes: Investigating the Impact of Poly (ADP-ribose) polymerase (PARP) Inhibitors
    Room: Exhibition
    Presenting Author: Roelof H. Bekendam, MD, PhD – Beth Israel Deaconess Medical Center
    Co-Author: Andrew Stone – Boston Children's Hospital
    Co-Author: Isabelle C. Becker, PhD – Boston Children's Hospital
    Co-Author: Virginia Camacho – Boston Children's Hospital
    Co-Author: Kellie Machlus, PhD – Boston Children's Hospital
    Co-Author: Joseph Italiano – Boston Children's Hospital
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0379 - Study of Megakaryocytes in Systemic Lupus Erythematosus
    Room: Exhibition
    Presenting Author: Isabelle Allaeys – Centre de recherche du CHU de Québec-Université Laval
    Co-Author: Andrew Stone – Boston Children's Hospital
    Co-Author: Julia Tilburg, PhD – Boston Children's Hospital
    Co-Author: Mickael Leclercq – Centre de recherche du CHU de Québec-Université Laval
    Co-Author: Arnaud Droit – Centre de recherche du CHU de Québec-Université Laval
    Co-Author: Kellie Machlus, PhD – Boston Children's Hospital
    Co-Author: Eric Boilard, PhD (he/him/his) – Centre de Recherche du CHU de Québec- Université Laval
    Co-Author: Julie Portal
    Co-Author: Martin Pelletier
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0380 - Corrections of Bernard Soulier Syndrome Megakaryocyte Phenotypes by Small Molecules and Interleukin-1α
    Room: Exhibition
    Presenting Author: Ponlapat Rojnuckarin, MD, PhD (he/him/his) – Excellence Center in Translational Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Co-Author: Ponthip mekchay – Excellence Center in Translational Hematology, Division of Hematology, Faculty of Medicine, Chulalongkorn University
    Co-Author: Praewphan Ingrungruanglert – Stem Cell and Cell Therapy Research Unit, Faculty of Medicine, Chulalongkorn University
    Co-Author: Netchanok Leela-adisorn – Stem Cell and Cell Therapy Research Unit, Faculty of Medicine, Chulalongkorn University
    Co-Author: Noppacharn Uaprasert, MD – Excellence Center in Translational Hematology, Division of Hematology, Faculty of Medicine, Chulalongkorn University
    Co-Author: Nipan Israsena – Stem Cell and Cell Therapy Research Unit, Faculty of Medicine, Chulalongkorn University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0381 - Red blood cell inclusions of non-muscle myosin IIA associate with GATA1-related thrombocytopenia
    Room: Exhibition
    Presenting Author: Carlo Zaninetti, MD, PhD – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Leonard Vater – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: José RIVERA Rivera, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Jan Wesche – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Carmen Freyer – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Sandra Ohlenforst – Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany.
    Co-Author: Kathleen Freson, PhD – Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium.
    Co-Author: Andreas Greinacher, MD – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0384 - Spatiotemporal evolution of mammalian megakaryocytes during ontogeny
    Room: Exhibition
    Presenting Author: Cuicui Liu, PhD (she/her/hers) – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Meijuan Xia – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Jinjing Zhao – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Yezi Ma – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Minmin Li – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Pei Su – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Hongtao Wang – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Co-Author: Jiaxi Zhou, Ph.D – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0385 - Systemic lupus erythematosus-induced Amegakaryocytic Thrombocytopenia and Subsequent Aplastic Anemia
    Room: Exhibition
    Presenting Author: Gyuhee Seong, MD (she/her/hers) – SUNY Downstate Medical Center
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0386 - Increased platelet expression of the transcriptional suppressor ETV6 can be detected by immunofluorescence on the blood smear and associates with ETV6-related thrombocytopenia
    Room: Exhibition
    Presenting Author: Carlo Zaninetti, MD, PhD – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Marcel Baschin – Pädiatrischen Onkologie und Hämatologie der Klinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsmedizin Greifswald. Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Leonard Vater – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Anna Karastaneva – Division of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria.
    Co-Author: Susanne Holzhauer – Klinik für Pädiatrie mit Schwerpunkt Onkologie und Hämatologie, Universitätsmedizin Berlin.
    Co-Author: Carmen Freyer – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Markus G. Seidel – Division of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, Medical University of Graz, Graz, Austria.
    Co-Author: Andreas Greinacher, MD – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0387 - Characterising the molecular pathways controlled by ETV6 during megakaryopoiesis
    Room: Exhibition
    Presenting Author: Huan Zhang – Department of Haematopoiesis, Sanquin Research, Amsterdam, The Netherlands
    Co-Author: Elise J. Huisman, MD (she/her/hers) – Dpt of pediatric hematology and oncology
    Co-Author: Marten Hansen – Department of Haematopoiesis, Sanquin Research, Amsterdam, The Netherlands
    Co-Author: Arthur F. Svendsen – Department of Haematopoiesis, Sanquin Research, Amsterdam, The Netherlands
    Co-Author: Arie J. Hoogendijk, PhD – Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands.
    Co-Author: Emile van den Akker – Department of Haematopoiesis, Sanquin Research, Amsterdam, The Netherlands
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0390 - Identification of key regulators of procoagulant COAT platelet generation by quantitative phosphoproteomic analysis and phosphoflow
    Room: Exhibition
    Presenting Author: Lucas Veuthey, BSc, MSc (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Alessandro Aliotta, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Debora Bertaggia Calderara, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Cindy Pereira Portela, MD Student – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Durre Shehwar, MSc MPhil – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0392 - Probing Biosynthetic Pathways of Platelets
    Room: Exhibition
    Presenting Author: Katherine Badior, PhD – Versiti Blood Research Institute
    Co-Author: Jerry Leung (he/him/his) – The University of British Columbia
    Co-Author: Colton Strong (he/him/his) – The University of British Columbia
    Co-Author: Madelaine K. Robertson – University of British Columbia
    Co-Author: Pieter Cullis – The University of British Columbia
    Co-Author: Dana Devine – The University of British Columbia
    Co-Author: Eric Jan – University of British Columbia
    Co-Author: Christian Kastrup, PhD – Versiti Blood Research Institute
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0393 - Storage associated changes in apheresis platelet components using glycomics.
    Room: Exhibition
    Co-Author: Jessica Halliday – Institute for Glycomics; Griffith University; Institute for Glycomics
    Co-Author: Abarna Vidya Mohana Murugan – Institute for Glycomics; Griffith University; Institute for Glycomics
    Co-Author: Claire Linnane – R&D Australian Red Cross Lifeblood
    Co-Author: Thomas Hueneburg – R&D Australian Red Cross Lifeblood; University of Sydney
    Co-Author: Denese C. C. Marks – R&D Australian Red Cross Lifeblood; Sydney Medical School, University of Sydney
    Co-Author: Daniel Kolarich – Institute for Glycomics; Griffith University; Institute for Glycomics
    Presenting Author: Dianne E. Van Der Wal, PhD – R&D Australian Red Cross Lifeblood
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0394 - Argonaute2 (Ago2) modulates megakaryocyte development and platelet reactivity in a sex-specific manner via suppression of mitochondrial genes; evidence for diverse RNA granule species in platelets.
    Room: Exhibition
    Presenting Author: Lawrence E. Goldfinger, PhD (he/him/his) – Thomas Jefferson University
    Co-Author: Sophia Lazar – Thomas Jefferson University
    Co-Author: Jeremy Wurtzel – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0395 - De novo protein synthesis capacity of Tumor-educated platelets
    Room: Exhibition
    Presenting Author: Hiroki Tanaka – Department of Pathology, Division of Tumor Pathology
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0397 - Differential requirement for ligand valency in the activation of CLEC-2 in human and humanised mouse platelets
    Room: Exhibition
    Presenting Author: Joanne Clark, PhD – University of Birmingham
    Co-Author: Eleyna Martin – University of Birmingham
    Co-Author: Luis Moran – University of Birmingham
    Co-Author: Ying Di – University of Birmingham
    Co-Author: Helena Brown – University of Würzburg
    Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Co-Author: David Stegner, PhD (he/him/his) – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Co-Author: Angel Garcia – Universidade de Santiago de Compostela
    Co-Author: Steve Watson – University of Birmingham
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0398 - Platelet β1 and β3 integrins play a key role in hemostasis, arterial thrombosis and tumor metastasis
    Room: Exhibition
    Presenting Author: Alexandra A. Yakusheva, PhD – Etablissement Français du Sang GRAND EST
    Co-Author: Emily Janus-Bell, PhD (she/her/hers) – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Clarisse Mouriaux – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Catherine Bourdon – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Maria Garcia-Leon – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS)
    Co-Author: Olivier Lefebvre – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS)
    Co-Author: Jacky Goetz – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS)
    Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0399 - The NMDA receptor regulates integrin activation and arterial thrombosis through store-operated Ca2+ entry in platelets
    Room: Exhibition
    Co-Author: Friedrich WB Reusswig – Department of Vascular- and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany
    Co-Author: Münthea Yilmaz – Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany
    Co-Author: Marius Brechtenkamp – 1Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany
    Presenting Author: Sevgi C. Cengiz, PhD (she/her/hers) – Institute of Experimantal Vascular Medicine
    Co-Author: Irena Krüger – 1Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany
    Co-Author: Eckhard Lammert – Institute of Metabolic Physiology, Heinrich-Heine University, Düsseldorf, Germany
    Co-Author: Nikolaj Klöcker – Institute of Neural and Sensory Physiology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany
    Co-Author: Margitta Elvers – Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany.
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0400 - The Janus-face of platelet PAR4: dose-dependent host protective and detrimental roles in influenza A virus infection of mice.
    Room: Exhibition
    Presenting Author: Silvio Antoniak (he/him/his) – UNC Blood Research Center
    Co-Author: Swati Sharma (she/her/hers) – UNC Chapel Hill
    Co-Author: Lauryn Ursery – UNC Blood Research Center
    Co-Author: Aymen Elzawam – UNC Blood Research Center
    Co-Author: Willie Williams – UNC Blood Research Center
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0401 - Inhibition of thrombin-mediated GPV cleavage ameliorates bleeding defects in a broad range of pathological conditions
    Room: Exhibition
    Presenting Author: Patricia Öftering, MSc – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Co-Author: David Stegner, PhD (he/him/his) – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Co-Author: Sarah Beck, PhD – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0402 - The FcγRIIA receptor does not play a critical role in hemostasis and thrombosis in the absence of immune complexes
    Room: Exhibition
    Presenting Author: Florian Tupin, MSc – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Stephanie Magnenat – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Clarisse Mouriaux – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Béatrice Hechler, PhD – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0403 - A Common Variant in GRK5 Reveals a PAR1-Specific Regulation in Platelets
    Room: Exhibition
    Co-Author: Yanki Yarman – Thomas Jefferson University
    Co-Author: Xuefei Zhao, MS – Thomas Jefferson University
    Co-Author: Matthew Cooper – Thomas Jefferson University
    Co-Author: Hannah Thomson – Thomas Jefferson University
    Co-Author: Stephanie Renna – Thomas Jefferson University
    Co-Author: Steven E McKenzie, MD, PhD – Thomas Jefferson University
    Presenting Author: Peisong Ma, PhD – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0404 - A Mouse Model of the PAR4 Sequence Variant P310L Shows Decreased Platelet Reactivity and Thrombosis
    Room: Exhibition
    Presenting Author: Elizabeth A. Knauss – Case Western Reserve University
    Co-Author: Xu Han – Case Western Reserve University
    Co-Author: Wei li, MD, PhD – Marshall University
    Co-Author: Maria de la Fuente – Department of Pharmacology, CWRU School of Medicine, Cleveland, OH, USA.
    Co-Author: Marvin T. Nieman, PhD – Case Western Reserve University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0405 - Characterization of TLT-1 and P-selectin double null mouse in hemostatic and immune function
    Room: Exhibition
    Presenting Author: Barbara Manfredi, PhD (she/her/hers) – Oakland University
    Co-Author: Anthony V. Washington, PhD – Oakland University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0406 - Human platelets and megakaryocytes express precursor forms of neurotrophins and their respective receptors
    Room: Exhibition
    Presenting Author: Imane Boukhatem, MSc – Faculty of pharmacy, University of Montreal
    Co-Author: Mélanie Welman, PhD (she/her/hers) – Montreal Heart Institute
    Co-Author: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0408 - Regulation of collagen binding integrins by alpha 7 and C helix
    Room: Exhibition
    Presenting Author: Samir William Hamaia – University of Cambridge (UK)
    Co-Author: Antony P. Jackson – University of Cambridge (UK)
    Co-Author: Richard Farndale – University of Cambridge (UK)
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0409 - Inhibition of the p75 pan neurotrophic receptor partly inhibits BDNF-induced platelet aggregation
    Room: Exhibition
    Presenting Author: Samuel Fleury, MSc (he/him/his) – Faculty of pharmacy, University of Montreal
    Co-Author: Imane Boukhatem, MSc – Faculty of pharmacy, University of Montreal
    Co-Author: Mélanie Welman, PhD (she/her/hers) – Montreal Heart Institute
    Co-Author: Bruce Allen – Faculty of medicine, University of Montreal
    Co-Author: Uri Saragovi – McGill University
    Co-Author: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0410 - Difluorinated Thromboxane A2 Reveals Crosstalk Between Platelet Activatory and Inhibitory Pathways by Targeting Both the TP and IP Receptor.
    Room: Exhibition
    Presenting Author: Megan F. Allen, MRes (she/her/hers) – University of Bristol
    Co-Author: James L. Hutchinson – University of Bristol
    Co-Author: Michael Keith, Msci – University of Bristol
    Co-Author: Justin S. Trory – University of Bristol
    Co-Author: Stuart J. Mundell – University of Bristol
    Co-Author: Varinder K. Aggarwal – University of Bristol
    Co-Author: Ingeborg Hers, PhD – University of Bristol
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0411 - Platelet glycoprotein IIb- and IIIa levels are altered in persistently lupus anticoagulant positive patients with a history of thrombosis
    Room: Exhibition
    Presenting Author: Theresa Schramm, MSc – Department of Medicine I, Clinical Division of Haematology and Haemostaseology; Medical University of Vienna, Vienna, Austria
    Co-Author: Anahita Sedighi – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Austria
    Co-Author: Felicia Hsu – Institute of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria
    Co-Author: Ingrid Pabinger, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Cihan Ay, MD (he/him/his) – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Johanna Gebhart, MD, PhD (she/her/hers) – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Co-Author: Maria Zellner – Institute of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0412 - Simulating the Impact of Thrombin on Platelet Function Requires Simultaneous Activation of Both PAR-1 and PAR-4
    Room: Exhibition
    Presenting Author: Amihai Rottenstreich – Laboratory of Blood and Vascular Biology, Rockefeller University, New York, United States
    Co-Author: Jihong Li – Laboratory of Blood and Vascular Biology, Rockefeller University, New York, United States
    Co-Author: Lorena Buitrago – Laboratory of Blood and Vascular Biology, Rockefeller University, New York, United States
    Co-Author: Barry S. Coller – Laboratory of Blood and Vascular Biology, Rockefeller University, New York, United States
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0413 - Analyzing Moesin and Human TREM-like Transcript-1 (hTLT-1) Binding and Interaction
    Room: Exhibition
    Presenting Author: Javier A. Menendez, MLS (ASCP) (he/him/his) – Oakland University
    Co-Author: Anthony V. Washington, PhD – Oakland University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0415 - The role of filamin A in platelet thromboxane A2 secretion
    Room: Exhibition
    Presenting Author: Steven Z. Jiang (he/him/his) – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Co-Author: Kalyan Golla – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Co-Author: Hugh Kim – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0416 - Platelet polyphosphate activates NFκB signaling to induce myofibroblast differentiation
    Room: Exhibition
    Co-Author: Patrick Suess, PhD – University of Michigan Medical School
    Co-Author: Chanel La – University of British Columbia
    Co-Author: Sreeparna Vappala, PhD (she/her/hers) – University of British Columbia
    Co-Author: Jayachandran N. Kizhakkedathu, PhD (he/him/his) – Centre for Blood Research, University of British Columbia
    Presenting Author: James H. Morrissey, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0417 - ASK1 Regulates Thrombin, But Not Collagen Induced TxA2 Generation in Human Platelets
    Room: Exhibition
    Presenting Author: Manjuprasanna Voddarahalli Nagaraju, Masters (he/him/his) – Cardeza Center for Hemostasis, Thrombosis, and Vascular Biology, Cardeza Foundation for Hematologic Research, Department of Medicine, Thomas Jefferson University
    Co-Author: Meghna U. Naik, MS – Thomas Jefferson University
    Co-Author: John C. Kostyak, PhD – THOMAS JEFFERSON UNIVERSITY
    Co-Author: Ulhas P. Naik – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0419 - The molecular basis of carrageenan-induced thrombosis involves platelet activation via C-type lectin like receptor 2 (CLEC-2)
    Room: Exhibition
    Presenting Author: Ryohei Yokomori, MD – Clinical and Laboratory Medicine, University of Yamanashi
    Co-Author: Toshiaki Shirai, PhD – Clinical and Laboratory Medicine, University of Yamanashi
    Co-Author: Saori Ohishi – Clinical and Laboratory medicine, University of Yamanashi
    Co-Author: Tomoyuki Sasaki – Clinical and Laboratory medicine, University of Yamanashi
    Co-Author: Nagaharu Tsukiji – Clinical and Laboratory medicine, University of Yamanashi
    Co-Author: Katsuhiro Takano – Clinical and Laboratory medicine, University of Yamanashi
    Co-Author: Katsue Suzuki-Inoue, MD, PhD – Clinical and Laboratory medicine, University of Yamanashi
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0421 - Phosphoproteomics and systems analysis reveal protein kinase C theta (PKCθ) signaling events associated with the generation of procoagulant platelets
    Room: Exhibition
    Co-Author: Yiheng Zhang, MD – Oregon Health & Science University
    Co-Author: Stéphanie E. Reitsma, PhD – Department of Pathology and Laboratory Medicine, UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Co-Author: Ozgun Babur – UMass Boston
    Co-Author: Alexander Melrose – Oregon Health & Science University
    Co-Author: Jiaqing Pang – Oregon Health & Science University
    Co-Author: Stefanie Hodapp – University of California, San Diego
    Co-Author: Alexandra Newton – University of California, San Diego
    Co-Author: Phillip Wilmarth – Oregon Health & Science University
    Co-Author: Ashok Reddy – Oregon Health & Science University
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Presenting Author: Joseph E. Aslan, PhD – Oregon Health & Science University
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0422 - The piperazinyl-purine analogue MK177 is a bifunctional drug with promising anti-ischemic and anti-thrombotic potential
    Room: Exhibition
    Co-Author: Maria Koufaki – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Madelene Lindkvist – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Co-Author: Theano Fotopoulou – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Hayat Nuru – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Co-Author: Maria Zervou – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Josef Jakobsson – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Co-Author: Dimitra Pournara – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Eleni Ifanti – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Eftichia Kritsi – Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece
    Co-Author: Kristofer Nilsson – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Co-Author: Eva Lindström – Department of Biomedical and Clinical Sciences, Linköping University, Sweden
    Co-Author: Karin H. Fransén – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Presenting Author: Sofia Ramström, PhD, Associate Professor (she/her/hers) – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Co-Author: Magnus Grenegård – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0423 - Protein phosphatase 1 alpha from platelets dampen endotoxin -induced proinflammatory signaling and kidney tubular apoptosis and injury
    Room: Exhibition
    Co-Author: Deepika Subramanyam – Baylor College of Medicine/Center for Translational Research on Inflammatory Diseases
    Co-Author: Marina Martinez-Vargas – Baylor College of Medicine/Center for Translational Research on Inflammatory Diseases
    Co-Author: Subhashree Pradhan – Baylor College of Medicine
    Co-Author: Arun Saini, MD – Baylor College of Medicine
    Co-Author: Miguel A. Cruz, PhD – Baylor College of Medicine
    Co-Author: Trung C. Nguyen, MD – Baylor College of Medicine/Texas Children's Hospital
    Presenting Author: K. Vinod Vijayan, Ph.D – Baylor Collège of Medicine
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0424 - The critical role of filamin A in the platelet shape change reaction
    Room: Exhibition
    Presenting Author: Felix Hong, MA (he/him/his) – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Co-Author: Enoli De Silva – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Co-Author: Hugh Kim – Centre for Blood Research, University of British Columbia, Vancouver, Canada
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0425 - STING stimulation drives a type-I IFN response in megakaryocytes and potentiates the activation of platelets
    Room: Exhibition
    Presenting Author: Genevieve Pepin, PhD, MBA – Université Du Québec à Trois-RIvières
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0427 - The Role of Mitochondrial Calcium Uniporter in Platelet Signaling
    Room: Exhibition
    Presenting Author: Durre Shehwar, MSc MPhil – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Alessandro Aliotta, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Saima Barki – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Debora Bertaggia Calderara, PhD – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Lucas Veuthey, BSc, MSc (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Cindy Pereira Portela, MD Student – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Muhammad Rizwan Alam – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Platelets and Megakaryocytes
  • Sunday, Jun 25th
    18:30 – 19:30 ET
    PB0429 - Potential difference in platelet aggregation between clinical dexmedetomidine and experimental medetomidine due to dose differences.
    Room: Exhibition
    Presenting Author: Kazunao Kondo, MD (he/him/his) – Fujita Health University
    Co-Author: Taiki Kano – Fujita Health University
    Co-Author: Yui Suganuma – Fujita Health University
    Co-Author: Kazuhisa Ikemoto – Fujita Health University
    Co-Author: Chiho Sumi-Ichunose – Fujita Health University
    Co-Author: Toshiaki Mochizuki – Fujita-Health University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    10:45 – 12:00 ET
    OC 39.6 - Platelet Production from Megakaryocytes
    Room: 515
    Moderator: Kellie Machlus, PhD – Boston Children's Hospital
    Moderator: Eric Boilard, PhD (he/him/his) – Centre de Recherche du CHU de Québec- Université Laval
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    10:45 – 11:00 ET
    OC 39.1 - Anti-integrin immune thrombocytopenia autoantibodies impair megakaryocyte migration, polarization and proplatelet formation.
    Room: 515
    Presenting Author: Francesca Tondi, MS – University of Perugia, Departement of Medicine and Surgery, Section of Internal and Cardiovascular Medicine
    Co-Author: Elisa Giglio – Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia
    Co-Author: Eleonora Petito, Post Doc – Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia
    Co-Author: Loredana Bury, PhD – Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia
    Co-Author: Paolo Gresele, MD, PhD – Dept. of Medicine and Surgery, University of Perugia
    Co-Author: Anna Maria Mezzasoma – Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    11:00 – 11:15 ET
    OC 39.2 - Megakaryocytes derived from human CD34+ cells express and release Brain-Derived Neurotrophic Factor
    Room: 515
    Presenting Author: Imane Boukhatem, MSc – Faculty of pharmacy, University of Montreal
    Co-Author: Mélanie Welman, PhD (she/her/hers) – Montreal Heart Institute
    Co-Author: Sonia POIRAULT-CHASSAC – Neurocentre Magendie, INSERM U1215, Bordeaux Neurocampus, Bordeaux, France
    Co-Author: Christilla BACHELOT-LOZA – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Pascale Gaussem – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Bruce Allen – Faculty of medicine, University of Montreal
    Co-Author: Guillaume Lettre – Faculty of medicine, University of Montreal
    Co-Author: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    11:15 – 11:30 ET
    OC 39.3 - Platelet Biogenesis from Mouse Megakaryocytes at Variable Shear Stress Levels by Using Microfluidic Systems
    Room: 515
    Co-Author: Semra Z. Birol, PhD – School of Physiology, Pharmacology and Neuroscience/University of Bristol
    Presenting Author: Jordan Vautrinot, Bsc – University of bristol
    Co-Author: Xiaojuan Zhao – School of Physiology, Pharmacology and Neuroscience/University of Bristol
    Co-Author: Muhammed E. Polat – Faculty of Mechanical Engineering/Istanbul Technical University
    Co-Author: Sertac Cadirci – Faculty of Mechanical Engineering/Istanbul Technical University
    Co-Author: Levent Trabzon – Faculty of Mechanical Engineering/Istanbul Technical University
    Co-Author: Alastair W. Poole – School of Physiology, Pharmacology and Neuroscience/University of Bristol
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    11:30 – 11:45 ET
    OC 39.4 - Use of an in vitro platelet production approach to assess the effects of chronic cigarette and e-cigarette exposure on platelet generation and function.
    Room: 515
    Presenting Author: Jordan Vautrinot, Bsc – University of bristol
    Co-Author: Xiaojuan Zhao – School of Physiology, Pharmacology and Neuroscience/University of Bristol
    Co-Author: Christopher M. Williams – University of bristol
    Co-Author: Alastair W. Poole – School of Physiology, Pharmacology and Neuroscience/University of Bristol
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    11:45 – 12:00 ET
    OC 39.5 - Lung megakaryocytes are tissue resident, arise independent of HSCs, and contribute to recovery in low platelet states.
    Room: 515
    Presenting Author: Alison C. Livada, MS (she/her/hers) – University of Rochester
    Co-Author: Sara Ture – University of Rochester
    Co-Author: Kathleen McGrath – University of Rochester
    Co-Author: James Palis – University of Rochester
    Co-Author: Craig N. Morrell, DVM, PhD (he/him/his) – University of Rochester
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0861 - Endoplasmic Reticulum (ER) stress is increased in diabetic platelets and contributes to platelet hyperactivity
    Room: Exhibition
    Presenting Author: Yvonne X. Kong, FRACP, FRCPA, MBBS, MSc – Haematology Research Group, Charles Perkins Centre, University of Sydney
    Co-Author: Rajan Rehan – Department of Cardiology, Royal Prince Alfred Hospital
    Co-Author: Fay Ghani – Haematology Research Group, Charles Perkins Centre, University of Sydney
    Co-Author: Jemma Fenwick – Haematology Research Group, Charles Perkins Centre, University of Sydney
    Co-Author: Declan Robertshaw – Sydney Medical School, University of Sydney
    Co-Author: Vincent Trang – Sydney Medical School, University of Sydney
    Co-Author: Soren Madsen – David James Lab, Charles Perkins Centre, University of Sydney
    Co-Author: Meg Potter – David James Lab, Charles Perkins Centre, University of Sydney
    Co-Author: Kristen Cooke – David James Lab, Charles Perkins Centre, University of Sydney
    Co-Author: Jacqueline Stoeckli – Molecular Cell Biology, School of Life and Environmental Sciences, University of Sydney
    Co-Author: Grant Morahan – Cardiovascular Science and Diabetes Program, Harry Perkins Institute of Medical Research, Western Australia
    Co-Author: Sian Cartland – Vascular Complications Group, Heart Research Institute
    Co-Author: Mary Kavurma – Vascular Complications Group, Heart Research Institute
    Co-Author: Michelle Cielesh – Larance Laboratory, Charles Perkins Centre, University of Sydney
    Co-Author: Yunwei Zhang – Sydney Precision Bioinformatics, University of Sydney
    Co-Author: Jean Yang – Sydney Precision Bioinformatics, University of Sydney
    Co-Author: David James – David James Lab, Charles Perkins Centre, University of Sydney
    Co-Author: James Weaver – Department of Cardiology, Royal Prince Alfred Hospital
    Co-Author: Mark Larance – Larance Laboratory, Charles Perkins Centre, University of Sydney
    Co-Author: Freda Passam – Haematology Research Group, Charles Perkins Centre, University of Sydney
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0863 - Fatty acid oxidation fuels agonist-induced platelet activation and thrombus formation: Targeting beta-oxidation of fatty acids as an effective anti-platelet strategy
    Room: Exhibition
    Presenting Author: Paresh P. Kulkarni, MBBS, MD, PhD (he/him/his) – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Mohammad Ekhlak – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Vipin Singh – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Vikas Kailashiya – Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Nitesh Singh – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Debabrata Dash – Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0864 - Platelet secretion in wound healing: the essence of α-granule endocytosis, biogenesis, and release kinetics
    Room: Exhibition
    Presenting Author: Daniëlle M. Coenen, MSc, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Sidney W. Whiteheart – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0865 - Endothelial Extracellular Vesicles Regulate In Situ Pulmonary Thrombosis in Sickle Cell Disease
    Room: Exhibition
    Presenting Author: Tomasz Brzoska, PhD (he/him/his) – University of Pittsburgh
    Co-Author: Tomasz W. Kaminski, PharmD – University of Pittsburgh
    Co-Author: Elizaveta V. Menchikova – University of Pittsburgh
    Co-Author: Omika Katoch – University of Pittsburgh
    Co-Author: Rikesh K. Dubey – University of Pittsburgh
    Co-Author: Stevan P. Tofovic – University of Pittsburgh
    Co-Author: Edwin K. Jackson – University of Pittsburgh
    Co-Author: Prithu Sundd, PhD (he/him/his) – University of Pittsburgh
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0866 - Glycoprotein VI: an interesting target to prevent early stent thrombosis?
    Room: Exhibition
    Presenting Author: Axelle KERN, MSc – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Dihia CHEBBAH – Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Raoul Pop – Interventional Neuroradiology Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Anne LEJAY – Vascular Surgery and Renal Transplantation Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Nabil CHAKFE – Vascular Surgery and Renal Transplantation Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Netanel KORIN – Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel
    Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0867 - Alpha-2-macroglobulin precludes platelet aggregation in response to the Brain-Derived Neurotrophic Factor (BDNF)
    Room: Exhibition
    Presenting Author: Georges JOURDI, PharmD, PhD (he/him/his) – Université Paris Cité and APHP. Nord
    Co-Author: Imane Boukhatem, MSc – Faculty of pharmacy, University of Montreal
    Co-Author: Pablo Barcelona – Ciudad Universitaria
    Co-Author: Samuel Fleury, MSc (he/him/his) – Faculty of pharmacy, University of Montreal
    Co-Author: Mélanie Welman, PhD (she/her/hers) – Montreal Heart Institute
    Co-Author: Uri Saragovi – McGill University
    Co-Author: Samuela Pasquali – Cibles Thérapeutiques et Conception de Médicaments CiTCoM -UMR8038 CNRS, Paris, France
    Co-Author: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0868 - Dynamics of alpha-granule secretion and cytoskeletal arrangements in spreading platelets
    Room: Exhibition
    Co-Author: Smita Patil – RCSI University of Medicine and Health Sciences
    Presenting Author: Ingmar Schoen, PhD (he/him/his) – RCSI University of Medicine and Health Sciences
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0869 - Platelet-derived microvesicles have a reparative role for muscle damage induced by hypothermia
    Room: Exhibition
    Presenting Author: Kie Horioka, PhD – Department of Forensic Medicine, Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu
    Co-Author: Hiroki Tanaka – Department of Pathology, Division of Tumor Pathology
    Co-Author: Akira Hayakawa – Department of Legal Medicine, Gunma University Graduate School of Medicine
    Co-Author: Lasse Pakanen – Department of Forensic Medicine, Research Unit of Internal Medicine, Medical Research Center Oulu,University of Oulu
    Co-Author: Katja Porvari – Department of Forensic Medicine, Research Unit of Internal Medicine, Medical Research Center Oulu,University of Oulu
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0870 - The Role of Cysteine String Protein-α in Platelet Exocytosis
    Room: Exhibition
    Presenting Author: Alexis N. Smith (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Linda Omali – University of Kentucky
    Co-Author: Daniëlle M. Coenen, MSc, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Smita Joshi, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Sidney W. Whiteheart – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0872 - MicroRNA-223-3p is a regulator of platelet procoagulant activity
    Room: Exhibition
    Co-Author: Julia Charlon – Geneva Platelet Group, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Co-Author: Sylvie Dunoyer-Geindre – Geneva Platelet Group, Faculty of Medicine, University of Geneva
    Co-Author: Severine Nolli – Geneva Platelet Group, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Co-Author: Paulina Ciepla – Geneva Platelet Group, Faculty of Medicine, University of Geneva
    Co-Author: Jean-Luc Reny, MD, PhD (he/him/his) – Geneva Platelet Group, Faculty of Medicine, University of Geneva
    Presenting Author: Pierre Fontana, MD PhD (he/him/his) – Division of Angiology and Haemostasis, University Hospitals of Geneva, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0873 - Small-molecule cyclophilin inhibitors potently reduce platelet procoagulant activity
    Room: Exhibition
    Presenting Author: Jens Van Bael – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Co-Author: Aline Vandenbulcke – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Co-Author: Abdelhakim Ahmed-Belkacem – INSERM U955, Team Viruses, Hepatology Cancer, Créteil, France
    Co-Author: Jean-François Guichou – Centre de Biologie Structurale (CBS), INSERM U1054, CNRS UMR5048, Université de Montpellier, Montpellier, France
    Co-Author: Jean-Michel Pawlotsky – INSERM U955, Team Viruses, Hepatology Cancer, Créteil, France
    Co-Author: Jelle Samyn – Laboratory for Thrombosis Research, KU Leuven Campus Kulak, Kortrijk, Belgium
    Co-Author: Arjan D. Barendrecht – Department of CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Coen Maas, PhD – CDL Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
    Co-Author: Simon F. De Meyer – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Co-Author: Karen Vanhoorelbeke, PhD – KU Leuven
    Co-Author: Claudia Tersteeg – Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0874 - The ins and outs of platelet contractility during thrombus formation
    Room: Exhibition
    Co-Author: Martin Kenny, MSc, PhD – University College Dublin
    Co-Author: Dishon W. Hiebner, MSc, PhD – RCSI University of Medicine and Health Sciences
    Co-Author: Sebastian Lickert – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich
    Presenting Author: Ingmar Schoen, PhD (he/him/his) – RCSI University of Medicine and Health Sciences
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0875 - A parallel kinetic Monte Carlo simulation of human stenotic thrombus growth with single platelet resolution from plaque rupture to occlusion
    Room: Exhibition
    Presenting Author: Kaushik N. Shankar, B.Tech. (he/him/his) – University of Pennsylvania
    Co-Author: Talid Sinno – University of Pennsylvania
    Co-Author: Scott Diamond, PhD – Institute for Medicine and Engineering, Dept. Chemical and Biomolecular Engineering, University of Pennsylvania
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0876 - Different agonists stimulate a unique signature of platelet surface markers dependent on aspirin status as determined by platelet mass cytometry
    Room: Exhibition
    Presenting Author: Melissa V. Chan, PhD – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Benjamin Spurgeon – Center for Platelet Research Studies, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts
    Co-Author: Bongani B. Nkambule – University of KwaZulu-Natal
    Co-Author: Amber Lachapelle – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Joseph Grech – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Andrew L. Frelinger, III – Center for Platelet Research Studies, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts
    Co-Author: Andrew D. D. Johnson, PhD (he/him/his) – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0877 - Menopause is associated with decreased platelet reactivity among women in the Framingham Heart Study
    Room: Exhibition
    Presenting Author: Robin E. Pashek – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Melissa V. Chan, PhD – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Bongani B. Nkambule – University of KwaZulu-Natal
    Co-Author: Florian Thibord, PhD – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Amber Lachapelle – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Ming-Huei Chen – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA
    Co-Author: Andrew D. D. Johnson, PhD (he/him/his) – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0878 - Platelet-derived mitochondria promote neutrophil activation and NETosis
    Room: Exhibition
    Presenting Author: Harriet E. Allan, PhD – Blizard Institute, Queen Mary University of London
    Co-Author: Nicola Dark – Blizard Institute, Queen Mary University of London
    Co-Author: Plinio Ferreira – Imperial College London
    Co-Author: Marilena Crescente, PhD – Manchester Metropolitan University
    Co-Author: Paul C. Armstrong, PhD – Blizard Institute, Queen Mary University of London
    Co-Author: Timothy D. Warner – Blizard Institute, Queen Mary University of London
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0879 - Structural Mechanisms and Kinetics of Blood Clot Contraction from in silico Modeling
    Room: Exhibition
    Co-Author: Valeri Barsegov – University of Massachusetts Lowell
    Co-Author: Evgenii Kliuchnikov – University of Massachusetts Lowell
    Co-Author: Kenneth A. Marx – University of Massachusetts Lowell
    Presenting Author: Rustem I. Litvinov, MD, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Alina D. D. Peshkova, PhD – University of Pennsylvania
    Co-Author: John W. Weisel, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0880 - The Brain-Derived Neurotrophic Factor (BDNF) sex-dependently affects platelet function in rats
    Room: Exhibition
    Presenting Author: Georges JOURDI, PharmD, PhD (he/him/his) – Université Paris Cité and APHP. Nord
    Co-Author: Mélanie Welman, PhD (she/her/hers) – Montreal Heart Institute
    Co-Author: Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers) – Faculty of pharmacy, University of Montreal
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0881 - Thrombin generation after initial cessation of bleeding is required for hemostatic plug stability via PAR-mediated platelet activation.
    Room: Exhibition
    Presenting Author: Christopher D. Mansi, MS – Thomas Jefferson University
    Co-Author: Joseph Wilhelm – Thomas Jefferson University
    Co-Author: Stephanie A. Renna – Thomas Jefferson University
    Co-Author: Kendra Williams – Thomas Jefferson University
    Co-Author: James V. Michael, PhD – Thomas Jefferson University
    Co-Author: Steven E McKenzie, MD, PhD – Thomas Jefferson University
    Co-Author: Timothy J. Stalker – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0882 - Contractility of Megakaryocytes and Platelets: Similarities and Distinctions
    Room: Exhibition
    Presenting Author: Oleg V. Kim, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Rustem I. Litvinov, MD, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: John W. Weisel, PhD – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Deborah L. French – Children's Hospital of Philadelphia
    Co-Author: Lawrence F. F. Brass – University of Pennsylvania
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0883 - Defining the Role of Hepcidin and Ferroportin Interactions in Regulating Platelet Function
    Room: Exhibition
    Presenting Author: Kylee Martens, MD (she/her/hers) – Oregon Health & Science University
    Co-Author: Alexander Melrose – Oregon Health & Science University
    Co-Author: Chih Jen Yang, MD – Oregon Health & Science University
    Co-Author: Micki Geffert – Oregon Health & Science University
    Co-Author: Jamie Lo – Oregon Health & Science University
    Co-Author: Joseph J. Shatzel – Oregon Health & Science University
    Co-Author: Joseph E. Aslan, PhD – Oregon Health & Science University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0884 - Development of a platform to study thrombogenicity of clinically-used stents
    Room: Exhibition
    Presenting Author: Kim JOUFFROY, DVM (she/her/hers) – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Axelle KERN, MSc – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Yevgeniy Kreinin – 2Department of Biomedical Engineering Technion, Israel Institute of Technology, Haifa, Israel
    Co-Author: Raoul Pop – Interventional Neuroradiology Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Netanel Korin – Department of Biomedical Engineering Technion, Israel Institute of Technology, Haifa, Israel
    Co-Author: Lise Charle – 1Université de Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0885 - β-amyloid peptide Aβ40 stimulates glycoprotein receptor GPVI signaling to generate procoagulant platelets
    Room: Exhibition
    Presenting Author: Yiheng Zhang, MD – Oregon Health & Science University
    Co-Author: Alexander Melrose – Oregon Health & Science University
    Co-Author: Jiaqing Pang – Oregon Health & Science University
    Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University
    Co-Author: Joseph E. Aslan, PhD – Oregon Health & Science University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0886 - Novel Small-Molecule Inhibitors of Clot Retraction and Thrombin-Induced Platelet Aggregation, that do not Inhibit PAR-1-Induced Platelet Aggregation.
    Room: Exhibition
    Presenting Author: claudia l. buitrago, PhD – The Rockefeller University
    Co-Author: Miriam-Rose Menezes – The Rockefeller University
    Co-Author: Chloe Larson – The Rockefeller University
    Co-Author: Fraser Glickman – The Rockefeller University
    Co-Author: Barry Coller – The Rockefeller University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0888 - The effect of polyphenols on platelet procoagulant activity and fibrin clot structure
    Room: Exhibition
    Presenting Author: Julia Sandrin Gauer, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds.
    Co-Author: Lutale M. Kaselampao – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds.
    Co-Author: Amanda D. V. MacCannell – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds.
    Co-Author: Lee D. Roberts – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds.
    Co-Author: Robert A. S. Ariens, PhD – Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0889 - Biodesigned recombinant protein mimicking activities of fibrillar collagen in primary haemostasis
    Room: Exhibition
    Presenting Author: Philippe Savard, MD (he/him/his) – Hématologie Biologique, CHU, Dijon Bourgogne
    Co-Author: David Vandroux – NVH Medicinal
    Co-Author: Morgane Pagniez – Laboratoire mixte, CHU Dijon Bourgogne
    Co-Author: Françoise Vaizan – Laboratoire mixte, CHU Dijon Bourgogne
    Co-Author: Tiffany Madranges – Laboratoire mixte, CHU Dijon Bourgogne
    Co-Author: Thomas Lecompte – Université de Lorraine, Nancy, France
    Co-Author: Emmanuel De Maistre – Hématologie Biologique, CHU, Dijon
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0890 - Discrimination of agonists-stimulated platelet phenotypes depending on pathogen inactivation and storage temperature in a blood bank
    Room: Exhibition
    Presenting Author: Charlotte Muret, MS – Transfusion Interrégionale CRS SA, Epalinges, Switzerland
    Co-Author: David Crettaz – Transfusion Interrégionale CRS SA, Epalinges, Switzerland
    Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Co-Author: Michel Prudent – Transfusion Interrégionale CRS SA, Epalinges, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0891 - Impact of enhanced platelet turnover on platelet reactivity in healthy humans
    Room: Exhibition
    Co-Author: Silas L. Schwarz – Universitätsmedizin Greifswald
    Presenting Author: Martina Wolff, MD (she/her/hers) – Universitätsmedizin Greifswald
    Co-Author: Andreas Greinacher, MD – Institut für Transfusionsmedizin, Universitätsmedizin Greifswald.
    Co-Author: Stefan Handtke – Universitätsmedizin Rostock
    Co-Author: Thomas Thiele, MD – Universitätsmedizin Rostock, Institut für Transfusionsmedizin
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0892 - C-3399 inhibitor of PDI isoforms with an attractive profile of antiplatelet action
    Room: Exhibition
    Presenting Author: Kamil Przyborowski, MPharm PhD – Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland
    Co-Author: Agnieszka Pelesz – Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland
    Co-Author: Filip Fedak – Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland
    Co-Author: Ivars Kalvins – Laboratory of Carbocyclic Compounds, Latvian Institute of Organic Synthesis, Riga, Latvia
    Co-Author: Kerstin Jurk, PhD – Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    Co-Author: Stefan Chlopicki – Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0893 - Characterization of the TLT-1 Fibrinogen ligand interaction.
    Room: Exhibition
    Presenting Author: Siobhan L. Branfield, MD (she/her/hers) – Oakland University
    Co-Author: Xariana Vales – UPR-RP
    Co-Author: Manuel A. Mosso-Pani, PhD, Msc, Bsc. – Oakland University
    Co-Author: Jose González – UPR-RP
    Co-Author: Pearl Akamine – UPR-RP
    Co-Author: Abel Baerga – UPR-RP
    Co-Author: Colin Wu – Oakland University
    Co-Author: Laura Campbell – Oakland University
    Co-Author: Anthony V. Washington, PhD – Oakland University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0894 - Evaluating platelet function post transfusion with cold-stored vs room temperature platelets in patients with traumatic brain injury
    Room: Exhibition
    Co-Author: Lara Hoteit, MD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Amudan J. Srinivasan, MD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Devin M. Dishong – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Emily P. Mihalko, PhD – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Ronit Kar – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: Nijmeh Alsaadi – Trauma and Transfusion Medicine Research Center, Department of Surgery, University of Pittsburgh
    Co-Author: David O. Okonkwo – Department of Neurosurgery, University of Pittsburgh
    Co-Author: Jason L. Sperry – Department of Surgery, University of Pittsburgh
    Co-Author: Susan M. Shea – Department of Surgery, Department of Bioengineering, University of Pittsburgh
    Presenting Author: Matthew D. Neal, MD FACS (he/him/his) – University of Pittsburgh
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0895 - Platelet activation and aggregation assays in Non-Human Primates for the evaluation of potential effects of new drugs in the context of non-clinical studies.
    Room: Exhibition
    Presenting Author: Anthony Pinçon, PhD – Charles River Laboratories
    Co-Author: Paolo Campoli – Charles River Laboratories
    Co-Author: Carolyne Dumont – Charles River Laboratories
    Co-Author: Marie-Soleil Piché – Charles River Laboratories
    Co-Author: Florence Poitout – Charles River Laboratories
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0896 - Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter global measure of haemostasis
    Room: Exhibition
    Presenting Author: Ruya Meltem Sariyer – Reading School of Pharmacy, University of Reading, Whiteknights, Reading, United Kingdom
    Co-Author: Kirandeep Kaur Gill – Department of Chemistry, University of Victoria, Victoria, British Columbia, Canada
    Co-Author: Daniel Hodge, MSc – Reading School of Biological Sciences, University of Reading, Whiteknights, Reading, United Kingdom
    Co-Author: Sarah H. Needs – Reading School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6UB, United Kingdom
    Co-Author: Nuno M. Reis – Department of Chemical Engineering and Centre for Biosensors, Bioelectronics and Biodevices (C3Bio), University of Bath, Bath BA2 7AY, United Kingdom
    Co-Author: Chris Jones – Reading School of Biological Sciences, University of Reading, Whiteknights, Reading, United Kingdom
    Co-Author: Alexander Edwards – Reading School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6UB, United Kingdom
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0898 - Comparative methods of platelet aggregation by light transmission in elderly patients
    Room: Exhibition
    Co-Author: Florencia Juguer – Hematology and Hemostasis Laboratory. César Milstein Hospital
    Co-Author: Rodolfo E. Sueldo, PhD – Laboratorio de Hematología y Hemostasia. Hospital César Milstein Laboratorio de Hemostasia. Servicio de Hematología y Oncología Hospital de Pediatría Prof. Dr. Juan P. Garrahan
    Co-Author: Monica Maggiolo – Laboratorio de Hematología y Hemostasia. Hospital César Milstein
    Co-Author: Alejandra Baques – Servicio de Hemofilia. Hospital César Milstein
    Presenting Author: Mirta del valle Arias, BSc – Laboratorio de Hematología y Hemostasia. Hospital César Milstein
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0899 - Connexin 45 is co-localized with Coxsackievirus-adenovirus receptor forming contact membrane within platelet aggregates and filopodia
    Room: Exhibition
    Presenting Author: Elena M. Rimskaya – National Medical Research Center of Cardiology named after academician E.I. Chazov
    Co-Author: Liudmila Buraychkovskaya – National Medical Research Center of Cardiology named after academician E.I. Chazov
    Co-Author: Natalia Mironova – National Medical Research Center of Cardiology named after academician E.I. Chazov
    Co-Author: Petr Chumachenko – National Medical Research Center of Cardiology named after academician E.I. Chazov
    Co-Author: Maha Othman, MD PhD – Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, Ontario, Canada,
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0900 - Developing standards to support platelets and platelet components
    Room: Exhibition
    Presenting Author: Sophie E. Cherrington, PhD (she/her/hers) – Immunohaematology and Autoimmunity, Standards Lifecycle, MHRA
    Co-Author: Holly R. Foster – Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Jeffrey Cheah Biomedical Centre
    Co-Author: Cedric Ghevaert, MD PhD – Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Jeffrey Cheah Biomedical Centre
    Co-Author: Dina Vara – Immunohaematology and Autoimmunity, Standards Lifecycle, Medicines and Healthcare Regulatory Agency (MHRA)
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0902 - The effect of hypercortisolism on platelet function in dogs with Cushing's syndrome
    Room: Exhibition
    Co-Author: Sanggu Kim – Chungbuk National University
    Co-Author: Dohee Lee – Chungbuk National University
    Co-Author: Preeti Kumari Chaudhary – Chungbuk National University
    Co-Author: Hakhyun Kim – Chungbuk National University
    Co-Author: Byeong-Teck Kang – Chungbuk National University
    Presenting Author: Soochong Kim, DVM, PhD – Chungbuk National University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0904 - A novel quantitative flow cytometry approach in determining platelet subpopulations and quantifying cell surface receptors
    Room: Exhibition
    Presenting Author: Bongani B. Nkambule – University of KwaZulu-Natal
    Co-Author: Robin E. Pashek – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Co-Author: Mellissa Chan – National Hear, Lung and Blood Institute, the Framingham Heart Study
    Co-Author: Andrew D. D. Johnson, PhD (he/him/his) – Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, USA.
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0905 - Assessment of therapeutic window for antiplatelet taking cardiology patients: Anysis-P2Y12 assay
    Room: Exhibition
    Co-Author: SunYoung Kim – Rheomeditech Inc.
    Presenting Author: Sehyun Shin, PhD (he/him/his) – Korea University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0906 - Modified Platelet Storage Devices to Improve Quality During Storagee
    Room: Exhibition
    Presenting Author: Nicolas Pereyra – The University of British Columbia
    Co-Author: Kai Yu – The University of British Columbia
    Co-Author: Jayachandran N. Kizhakkedathu, PhD (he/him/his) – Centre for Blood Research, University of British Columbia
    Co-Author: Dana Devine – The University of British Columbia
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0907 - Study to determine the effects of pneumatic chute system transport on biophysical properties and functional activity of platelet concentrates
    Room: Exhibition
    Presenting Author: Rutvi Gautam Dave, MBBS, MD, Post-Doctoral Fellow – Christian Medical College and Hospital Vellore
    Co-Author: Tulasi Geevar, MBBS, MD (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Joy Mammen – Christian Medical College and Hospital Vellore
    Co-Author: Gayathiri K. Chellaiya – Christian Medical College and Hospital Vellore
    Co-Author: John Gnanaraj – Christian Medical College and Hospital Vellore
    Co-Author: P Amalraj – Christian Medical College and Hospital Vellore
    Co-Author: Ramya Vijayan – Christian Medical College and Hospital
    Co-Author: Dolly Daniel – Christian Medical College and Hospital Vellore
    Co-Author: Sukesh Chandran Nair – Christian Medical College and Hospital Vellore
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0908 - Therapeutic efficacy of platelet-rich plasma in chronic compression of the dorsal root ganglion in rat
    Room: Exhibition
    Co-Author: Preeti Kumari Chaudhary – Chungbuk National University
    Co-Author: Jaisan Islam – Chungbuk National University
    Co-Author: Sanggu Kim – Chungbuk National University
    Co-Author: Elina KC – Chungbuk National University
    Co-Author: Young Seok Park – Chungbuk National University
    Presenting Author: Soochong Kim, DVM, PhD – Chungbuk National University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0909 - TREM-Like Transcript-1, a platelet receptor, as a potential regulator of hepatic regeneration post-surgical resection
    Room: Exhibition
    Presenting Author: Siobhan L. Branfield, MD (she/her/hers) – Oakland University
    Co-Author: Anthony V. Washington, PhD – Oakland University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0910 - Evaluation of the clot formation tranfusing fresh, cold and frozen platelets. Advantages for the military environment.
    Room: Exhibition
    Presenting Author: José R. Díaz-Valdés – University of Alcalá
    Co-Author: Ricardo Navarro-Suay – University of Alcalá
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0911 - Platelet reactivity in patients with Atrial Fibrillation and Coronary Artery Disease under IIa antagonists and Xa antagonists
    Room: Exhibition
    Presenting Author: K.L. Zheng, MD, PhD candidate, MPH – St. Antonius Nieuwegein, MUMC/CARIM
    Co-Author: W.L. Bor – St. Antonius Nieuwegein, MUMC/CARIM
    Co-Author: A. Verburg – St. Antonius Nieuwegein, MUMC/CARIM
    Co-Author: E Aarnink – St. Antonius Nieuwegein
    Co-Author: H Kelder – St. Antonius Nieuwegein
    Co-Author: C Hackeng – St. Antonius Nieuwegein
    Co-Author: J.M. Ten Berg – St. Antonius Nieuwegein, MUMC/CARIM
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0912 - Study to determine the minimum number of platelet events acquisition required for flow cytometry based platelet function testing in healthy controls and patients with thrombocytopenia
    Room: Exhibition
    Presenting Author: Rutvi Gautam Dave, MBBS, MD, Post-Doctoral Fellow – Christian Medical College and Hospital Vellore
    Co-Author: Tulasi Geevar, MBBS, MD (she/her/hers) – Christian Medical College and Hospital Vellore
    Co-Author: Joy Mammen – Christian Medical College and Hospital Vellore
    Co-Author: Gayathiri K. Chellaiya – Christian Medical College and Hospital Vellore
    Co-Author: Ramya Vijayan – Christian Medical College and Hospital
    Co-Author: Sukesh Chandran Nair – Christian Medical College and Hospital Vellore
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0913 - Desialylated platelets are involved in the proliferation of HepG2 cells
    Room: Exhibition
    Presenting Author: Ippei Noboruo (he/him/his) – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Co-Author: Mitsuhiro Uchiba – Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital
    Co-Author: Tatsuya Kawaguchi – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Co-Author: Masao Matsuoka – Department of Hematology, Rheumatology, and Infectious Diseases, Graduate School of Medical Sciences, Kumamoto University
    Co-Author: Yukinori Kozuma – Department of Medical Technology, Faculty of Health Science, Kumamoto Health Science University
    Platelets and Megakaryocytes
  • Monday, Jun 26th
    18:30 – 19:30 ET
    PB0915 - Desialylation of platelet induced by neuraminidase accelerates platelet aggregation and activation.
    Room: Exhibition
    Presenting Author: Hohomi Arao – Graduate School of Health Sciences, Division of Health Sciences, Kumamoto Health Science University
    Co-Author: Tatsuya Furugaki – Department of Clinical Engineering technologist center, University of Tsukuba Hospital
    Co-Author: Kano Tanabe – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Co-Author: Ippei Noboruo (he/him/his) – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Co-Author: Tatsuya Kawaguchi – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Co-Author: Yukinori Kozuma – Department of Medical Technology, Faculty of Health Sciences, Kumamoto Health Science University
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    07:00 – 07:45 ET
    MC 26.1 - Intravital Imaging
    Room: Stratton Room at the InterContinental Montreal
    Speaker: Craig Jenne, PhD (he/him/his) – University of Calgary
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    07:00 – 07:45 ET
    MC 28.1 - Platelet Flow Cytometry
    Room: La Galerie D'Art Room at the InterContinental Montreal
    Speaker: Sofia Ramström, PhD, Associate Professor (she/her/hers) – School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    07:00 – 07:45 ET
    MC 29.1 - Platelet Function Disorders
    Room: Belfour Room at the InterContinental Montreal
    Speaker: Diane Nugent, MD (she/her/hers) – CHOC Childrens and Center for Inherited Blood Disorders
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    08:00 – 09:15 ET
    SOA 17.4 - Marian A. Packham Memorial Lecture: Heterogeneity in Platelets and Their Responses
    Room: 511
    Moderator: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    Moderator: Elizabeth A. Middleton, MD – University of Utah
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    08:00 – 08:25 ET
    SOA 17.1 - Multi-Parameter Analysis of Platelet Function - Towards Personalized Therapy
    Room: 511
    Speaker: Jonathan M. Gibbins, PhD (he/him/his) – Institute for Cardiovascular and Metabolic Research, School of Biological sciences, University of Reading, Reading, UK
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    08:25 – 08:50 ET
    SOA 17.2 - Platelet Heterogeneity in Myeloproliferative Neoplasms
    Room: 511
    Speaker: Anandi Krishnan, PhD – Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    08:50 – 09:15 ET
    SOA 17.3 - Platelet Generation by Hematopoietic Stem Cells
    Room: 511
    Speaker: Camilla Forsberg, PhD – University of California Santa Cruz
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    10:45 – 12:00 ET
    OC 58.6 - Platelet Signaling
    Room: 515
    Moderator: Peisong Ma, PhD – Thomas Jefferson University
    Moderator: Georges JOURDI, PharmD, PhD (he/him/his) – Université Paris Cité and APHP. Nord
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    10:45 – 11:00 ET
    OC 58.1 - Circulating endoglin decreases platelet aggregation and thrombus formation through interaction with the αIIbβ3 integrin
    Room: 515
    Presenting Author: Elisa Rossi, PhD (she/her/hers) – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Miguel Pericacho – Department of Physiology and Pharmacology, University of Salamanca, Spain
    Co-Author: Alexandre KAUSKOT – INSERM U1176, Hôpital Bicêtre
    Co-Author: Luis Gamella-Pozuelo – Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
    Co-Author: Etienne Reboul – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Iles Saidi – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Alexandre Leuci – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Cristina Egido-Turrion – Department of Physiology and Pharmacology, University of Salamanca, Spain
    Co-Author: DIVINA El Hamaoui – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Aurore Marchelli – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Francisco J. Fernández – Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC),Madrid, Spain
    Co-Author: Isabelle Margaill – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Cristina Vega – Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC),Madrid, Spain
    Co-Author: Pascale Gaussem – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Samuela Pasquali – Cibles Thérapeutiques et Conception de Médicaments CiTCoM -UMR8038 CNRS, Paris, France
    Co-Author: David Smadja, PhD (he/him/his) – Université Paris Cité
    Co-Author: Christilla Bachelot-Loza – Université Paris Cité, INSERM U1140, Innovative Therapies in Haemostasis, France
    Co-Author: Carmelo Bernabeu – Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    11:00 – 11:15 ET
    OC 58.2 - Conformational Change in Platelet αIIbβ3 Induce PKC-dependent Serine 284 Phosphorylation of Junctional Adhesion Molecule-A and Rap1 Activation
    Room: 515
    Presenting Author: Meghna U. Naik, MS – Thomas Jefferson University
    Co-Author: Meghna U. Naik, MS – Thomas Jefferson University
    Co-Author: Ulhas P. Naik – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    11:15 – 11:30 ET
    OC 58.3 - Affinity of anti-GPVI antibodies determines the degree of human and mouse GPVI depletion in vivo
    Room: 515
    Presenting Author: Stefano Navarro, PhD (he/him/his) – University hospital Würzburg
    Co-Author: Sarah Beck, PhD – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Co-Author: Marijke Kuijpers – Maastricht University
    Co-Author: Johan W. M. Heemskerk – Synapse research insitute
    Co-Author: David Stegner, PhD (he/him/his) – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany
    Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    11:30 – 11:45 ET
    OC 58.4 - CIB1 Binding to Cytoplasmic Tail of αIIb Is Required for αIIbβ3 Activation in Platelets
    Room: 515
    Presenting Author: Deepa Gautam, PhD (she/her/hers) – Thomas Jefferson University
    Co-Author: Kalyan Golla – University of British Columbia
    Co-Author: Meghna U. Naik, MS – Thomas Jefferson University
    Co-Author: John C. Kostyak, PhD – THOMAS JEFFERSON UNIVERSITY
    Co-Author: Ulhas P. Naik – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    11:45 – 12:00 ET
    OC 58.5 - Cooperation between platelet β1 and β3 integrins in the arrest of bleeding under inflammatory conditions in mice
    Room: 515
    Presenting Author: Emily Janus-Bell, PhD (she/her/hers) – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Nicolas Receveur – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Luc Mercier – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Clarisse Mouriaux – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Béatrice Hechler, PhD – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Jochen Reiser – Department of Medicine, Rush University Medical Center, Kellogg Building, Suite 1003, Chicago, IL 60612, USA
    Co-Author: Benoît Ho-Tin-Noé, PhD – Université de Paris Descartes, INSERM, Hôpital Bichat, UMR-S1148, F-75000 Paris, France
    Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    14:45 – 16:00 ET
    OC 61.6 - Manipulating Platelet Function
    Room: 710A
    Moderator: Beatrice Hechler, PhD – Sante FR
    Moderator: Dianne E. Van Der Wal, PhD – R&D Australian Red Cross Lifeblood
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    14:45 – 15:00 ET
    OC 61.1 - Optimization and Delivery of Endogenous mRNA UTRs using LNPs to Control Exogenous Protein Expression in Platelets
    Room: 710A
    Presenting Author: Madelaine K. Robertson – University of British Columbia
    Co-Author: Jerry Leung (he/him/his) – The University of British Columbia
    Co-Author: Colton Strong (he/him/his) – The University of British Columbia
    Co-Author: Katherine Badior, PhD – Versiti Blood Research Institute
    Co-Author: Eric Jan – University of British Columbia
    Co-Author: Pieter Cullis – The University of British Columbia
    Co-Author: Christian Kastrup, PhD – Versiti Blood Research Institute
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    15:00 – 15:15 ET
    OC 61.2 - MiR-146a-mimic therapy modulates platelet reactivity preventing mortality caused by pulmonary embolism model
    Room: 710A
    Presenting Author: Sonia Aguila, PhD (she/her/hers) – Centro Regional de Hemodonación, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Juan carlos Garcia-Cañaveras – Biomarkers and Precision Medicine Unit, Instituto de Investigación Sanitaria Fundación Hospital La Fe, Valencia, Spain
    Co-Author: Ascension M M. De los Reyes-Garcia, MSc – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Laura Zapata-Martinez – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Nuria Garcia-Barbera – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Pedro J Guijarro – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: María Luisa Lozano – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain
    Co-Author: Bernard Payrastre – INSERM, UMR-S U1297 and University of Toulouse III, Institute of Cardiovascular and Metabolic Diseases (I2MC), CHU-Rangueil, laboratoire d'Hématologie, CHU de Toulouse, Toulouse, France
    Co-Author: José RIVERA Rivera, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Marie Pierre Gratacap – INSERM, UMR-S U1297 and University of Toulouse III, Institute of Cardiovascular and Metabolic Diseases (I2MC), CHU-Rangueil, Toulouse, France
    Co-Author: Agustin Lahoz – Biomarkers and Precision Medicine Unit, Instituto de Investigación Sanitaria Fundación Hospital La Fe, Valencia, Spain
    Co-Author: Marcin kortylewski – Center for Gene Therapy and Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, California, US
    Co-Author: Rocio Gonzalez-Conejero – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
    Co-Author: Constantino Martinez, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, IMIB-Pascual Parrilla, Murcia, Spain
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    15:15 – 15:30 ET
    OC 61.3 - CS585 is a novel and highly selective IP receptor agonist for prevention of thrombosis
    Room: 710A
    Co-Author: Sylviane Lambert – University of Michigan
    Co-Author: Livia Stanger – University of Michigan
    Co-Author: Adriana Yamaguchi – University of Michigan
    Co-Author: Pooja Yalavarthi – University of Michigan
    Co-Author: Andrew Rickenberg – University of Michigan
    Co-Author: Niklas Bergh – Institute of Medicine, University of Gothenburg
    Co-Author: Bjorn Dahlof – Institute of Medicine, University of Gothenburg
    Presenting Author: Michael Holinstat, PhD – University of Michigan
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    15:30 – 15:45 ET
    OC 61.4 - Manipulating platelet secretion to affect hemostasis
    Room: 710A
    Presenting Author: Smita Joshi, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Alexis N. Smith (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Hammodah R. Alfar – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Kanakanagavalli Shravani Prakhya, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Irina Pokrovskaya – University of Arkansas for Medical Sciences
    Co-Author: Harry Chanzu – GenScript
    Co-Author: Brian Storrie – University of Arkansas for Medical Sciences
    Co-Author: Sidney W. Whiteheart – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Platelets and Megakaryocytes
  • Tuesday, Jun 27th
    15:45 – 16:00 ET
    OC 61.5 - Plasma growth factors drive constitutive translation in circulating platelets to maintain protein homeostasis and regulate platelet GPCR reactivity and the hemostatic and thrombotic balance.
    Room: 710A
    Presenting Author: Lawrence E. Goldfinger, PhD (he/him/his) – Thomas Jefferson University
    Co-Author: Jeremy Wurtzel – Thomas Jefferson University
    Co-Author: Sophia Lazar – Thomas Jefferson University
    Co-Author: Shayan Askari – Thomas Jefferson University
    Co-Author: Xuefei Zhao – Thomas Jefferson University
    Co-Author: Jenna R. Severa, BS – Thomas Jefferson University
    Co-Author: James V. Michael, PhD – Thomas Jefferson University
    Co-Author: Steven E McKenzie, MD, PhD – Thomas Jefferson University
    Co-Author: Timothy J. Stalker – Thomas Jefferson University
    Co-Author: Peisong Ma, PhD – Thomas Jefferson University
    Platelets and Megakaryocytes