Professor Dept. of Medicine and Surgery, University of Perugia Perugia, Umbria, Italy
Please view the 2023 RPTH State-of-the-Art Illustrated Capsules here.
Learning Objectives:
understand the pathogenetic mechanisms of impaired megakaryopoiesis contributing to thrombocytopenia in patients with ITP.
recognize the effect of circulating autoantibodies against the main platelet surface glycoproteins, on the interaction between megakaryocytes and bone marrow extracellular matrix.
appreciate the detrimental impact of antiplatelet auto-antibodies on various steps of megakaryo/thrombopoiesis.
