OC 77 - Progress in Hemostasis Testing: Implications for Future Practice

Moderator(s)

• 

  Steve Kitchen, PhD

  Lead Scientist
  Department of Coagulation
  Sheffield Haemophilia and Thrombosis Centre
  sheffield, England, United Kingdom
• 

  Carolyne Elbaz, MDCM FRCPC MScCH

  Associate Member, Oncology
  Department of Medicine, McGill University
  Montreal, Quebec, Canada

Presentations:

• 10:15 – 10:30 ET

  Development, validation, and implementation of a decision support tool for the screening of mild bleeding disorders
  

  Presenting Author: Henning Nilius, MD, MSc (he/him/his) – Department of Clinical Chemistry, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland

  Co-Author: Jonas Kaufmann – Departement of Clinical Chemistry, Inselspital Bern University Hospital

  Co-Author: Marcel Adler – Departement of Hematology and Central Hematology Laboratory, Inselspital University Hospital Bern & CHUV Lausanne University Hospital

  Co-Author: Anna Wieland – Department of Hematology and Central Hematology Laboratory, Bern University Hospital, University of Bern, Switzerland

  Co-Author: Lorenzo Alberio, MD (he/him/his) – Division and Central Laboratory of Hematology, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland

  Co-Author: Gabor Erdös – Department of Anaesthesiology and Pain Therapy, Inselspital Bern University Hospital

  Co-Author: Thomas C. Sauter – Department of Emergency Medicine, Inselspital Bern University Hospita

  Co-Author: Andreas Koster – Institute of Anesthesiology and Pain Therapy, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum

  Co-Author: Jerrold H. Levy, MD (he/him/his) – Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine

  Co-Author: Michael Nagler, MD, PhD, MSc – Department of Clinical Chemistry, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
• 10:30 – 10:45 ET

  Discrepant low ACL TOP VWF:GP1bR result is frequent in unselected MPN patients and does not predict bleeding risk
  

  Presenting Author: Joseph Noye, MBBS, BSc – Department of Haematology, Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia

  Co-Author: Joanne Beggs – Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia

  Co-Author: Jane Mason – Queensland Haemophilia Centre, Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia
• 10:45 – 11:00 ET

  When is factor VIII deficiency not hemophilia A? Variant F8 c.1094 A>G, p.Tyr365Cys illustrates the utility of genotyping and the value of disease specific expertise in variant classification
  

  Presenting Author: Dominika A. Bajguz, MS, CGC (she/her/hers) – Versiti Diagnostic Laboratory

  Co-Author: Valerie Trapp-Stamborski – Versiti Diagnostic Laboratory

  Co-Author: Elizabeth L. Palmer, MS, CGC – Versiti Diagnostic Laboratory

  Co-Author: Candace C. Smith – Versiti Diagnostic Laboratories

  Co-Author: Curt D. Czajkowski – Versiti Diagnostic Laboratory

  Co-Author: Samantha J. Meyers – Versiti Diagnostic Laboratory

  Co-Author: Anna P. Miller – Versiti Diagnostic Laboratory

  Co-Author: Stefanie N. Dugan – Versiti Diagnostic Laboratory

  Co-Author: Kenneth D. Friedman – Versiti Diagnostic Laboratory

  Co-Author: Juliana Perez Botero – Versiti Diagnostic Laboratory
• 11:00 – 11:15 ET

  Predicting Bethesda inhibitor titers in Hemophilia A patients on the basis of screening assay results: Ways to economize the Bethesda Assay.
  

  Presenting Author: Dinesh Chandra, MD, DM – Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

  Co-Author: Ruchi Gupta – sanjay Gandhi PGIMS, Lucknow

  Co-Author: Prakhar Gupta – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: Khaliqur Rahman – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: sanjeev Yadav – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: Manish Kumar Singh – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: Prabhakar Mishra – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: Jayanta Kumar Biswas – Sanjay Gandhi PGIMS, Lucknow

  Co-Author: Rajesh Kashyap – Sanjay Gandhi PGIMS, Lucknow
• 11:15 – 11:30 ET

  Development of a Rapid and Fully Automated FVIII Inhibitor Assay Insensitive to the Presence of Emicizumab
  

  Presenting Author: Bert Verbruggen, PhD – Hemostad

  Co-Author: Nikolaus B. Binder, MD PhD – Technoclone Herstellung von Diagnostika und Arzneimitteln GmbH, Vienna, Austria

  Co-Author: Petra van Velp – Rock Consultancy, Bemmel, The Netherlands

  Co-Author: Robert Polenewen – Hemostad, Nijmegen, The Netherlands

  Co-Author: Gary W. Moore, DBMS – Department of Haematology, Specialist Haemostasis Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom