OC 56 - Hemostatic Mechanisms in Cancer and Autoimmunity

Moderator(s)

• 

  Marina Marchetti, PhD (she/her/hers)

  Hemostasis Lab Director
  Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy
  Bergamo, Lombardia, Italy
• 

  Wolfram Ruf, MD

  Scientific Director
  University Medicine of the Johannes Gutenberg University Mainz, Center for Thrombosis and Hemostasis (CTH)
  Mainz, Rheinland-Pfalz, Germany

Presentations:

• 10:45 – 11:00 ET

  Platelets as Versatile Effectors of Thromboinflammation: an MPN multi-omics collaborative
  

  Presenting Author: Sarah Kelliher, MB (she/her/hers) – UCD Conway SPHERE Research Group, Conway Institute, University College Dublin, Dublin, Ireland

  Co-Author: Sara Gamba – Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy

  Co-Author: Luisa Weiss, BSc, MSc, PhD – School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland

  Co-Author: Marina Marchetti, PhD (she/her/hers) – Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy

  Co-Author: Francesca Schieppati – Department of Immunohematology and Transfusion Medicine, "Papa Giovanni XXIII" Hospital, Bergamo, Italy

  Co-Author: Fionnuala Ní Áinle – Department for Haematology, Mater Misericordiae University Hospital, Dublin, Ireland

  Co-Author: Patricia B. Maguire, PhD – School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland

  Co-Author: Anna Falanga, MD (she/her/hers) – Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy

  Co-Author: Barry Kevane, MB PhD – Mater Misericordiae University Hospital & University College Dublin

  Co-Author: Anandi Krishnan, PhD – Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
• 11:15 – 11:30 ET

  Platelets transfected with a KRASG12D-silencing siRNA reduce pancreatic tumor mass in vivo in mice
  

  Presenting Author: Marco Malvestiti, PhD – Section of Internal and Cardiovascular Medicine, Dpt. of Medicine and Surgery. University of Perugia

  Co-Author: Giulio Purgatorio – University of Perugia

  Co-Author: Enrica Cesari – University of Perugia

  Co-Author: Francesca Tondi, MS – University of Perugia, Departement of Medicine and Surgery, Section of Internal and Cardiovascular Medicine

  Co-Author: Stefania Momi – University of Perugia

  Co-Author: Paolo Gresele, MD, PhD – Dept. of Medicine and Surgery, University of Perugia
• 11:30 – 11:45 ET

  GPVI-activated platelets drive the neutrophil profibrotic function in systemic sclerosis
  

  Presenting Author: Roxane Darbousset, PhD – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Spoorthi Balu – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Brian Wauford – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Marc Todd – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Pierre Cunin – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Margaret H. Chang – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.

  Co-Author: Eilish Dillon – Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA

  Co-Author: Mehreen Elahee – Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA

  Co-Author: Deepak A. Rao – Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital, Harvard Medical School, Boston MA, USA

  Co-Author: Peter A. Nigrovic – Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA.
• 11:45 – 12:00 ET

  Detection and inhibition of nascent vascular calcification with by protein S Gla-domain
  

  Presenting Author: Anouk Gentier, PhD (she/her/hers) – Department of BIochemistry, Cardiovascular Research Institute Maastricht, Maastricht University

  Co-Author: Stijn M. Agten, PhD – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University

  Co-Author: Leon J. Schurgers – Department of BIochemistry, Cardiovascular Research Institute Maastricht, Maastricht University

  Co-Author: Tilman M. Hackeng, PhD – Coagulation Profile, Maastricht, The Netherlands