OC 49 - Mechanisms of Cardiovascular and Neurologic Diseases

Moderator(s)

• 

  Alexandros Tselepis, MD, PhD

  Emeritus Professor of Biochemistry-Clinical Chemistry, MD, PhD
  Chemistry
  Atherothrombosis Research Centre/Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece
  Ioannina, Ioannina, Greece
• 

  Erin Norris, PhD (she/her/hers)

  Research Associate Professor
  The Rockefeller University
  New York, New York, United States

Presentations:

• 14:45 – 15:00 ET

  3K3A-Activated Protein C treatment exerts anti-inflammatory and blood barrier stabilizing effects in the retina, and inhibits choroidal neovascularization
  

  Presenting Author: Tami Livnat, Prof. (she/her/hers) – Tel Aviv University

  Co-Author: Yehonatan Weinberger – Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva, Israel

  Co-Author: José A Fernández – Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA

  Co-Author: Gil Ben-David – Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva, Israel

  Co-Author: Dahlia Palevski – Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva, Israel

  Co-Author: Ivan Budnik – University of IOWA

  Co-Author: Sarina Levy-Mendelovich, MD – The National Hemophilia Center, and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Ramat Gan, Israel

  Co-Author: Yael Nisgav – Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva, Israel

  Co-Author: Dov Weinberger – Rabin Medical Center, Ophthalmology Department and Laboratory of Eye Research Felsenstein Medical Research Center, Petah-Tikva, Israel

  Co-Author: Gili Kenet, MD – The National Hemophilia Center, and Amalia Biron Research Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Tel Aviv University, Tel Aviv, Israel

  Co-Author: John H. Griffin – Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA
• 15:00 – 15:15 ET

  Pharmacological targeting of the contact pathway attenuates experimental autoimmune encephalomyelitis in mice
  

  Presenting Author: Tia C.L Kohs, PhD (she/her/hers) – Oregon Health & Science University

  Co-Author: Meghan E. Fallon – Oregon Health & Science University

  Co-Author: Ethan C. Oseas, MS (he/him/his) – Oregon Health & Science University

  Co-Author: Laura Healy – Oregon Health & Science University

  Co-Author: Christina U. Lorentz – Aronora, Inc

  Co-Author: Erik I. Tucker – Aronora, Inc.

  Co-Author: Owen J.T McCarty, PhD, FAHA – Oregon Health & Science University

  Co-Author: David Gailani, MD – Vanderbilt University Medical Center

  Co-Author: Halina Offner – Oregon Health & Science University

  Co-Author: Norah G. Verbout, PhD – Aronora, Inc.
• 15:15 – 15:30 ET

  Modulating platelet-microglial complexes to limit neuroinflammation post-ischemic stroke
  

  Presenting Author: Joshua H. Bourne, PhD (he/him/his) – Monash University

  Co-Author: Althea Suthya – Monash University

  Co-Author: Jenny Wilson – Monash University

  Co-Author: Brooke Wanrooy – Monash University

  Co-Author: Michael Hickey – Monash University

  Co-Author: Connie Wong – Monash University
• 15:30 – 15:45 ET

  Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1 driven fibrotic remodeling, improves cardiac function and improves survival in ischemic heart failure
  

  Co-Author: Venkata Garlapati – Center for Thrombosis and Hemostasis, University Medical Center Mainz, Germany

  Co-Author: Michael Molitor – University Medical Center Mainz, Germany

  Co-Author: Thomas Michna – University Medical Center Mainz, Germany

  Co-Author: Stefanie Finger – University Medical Center Mainz, Germany

  Co-Author: Gergory Harms – University Medical Center Mainz, Germany

  Co-Author: Andreas Daiber – University Medical Center Mainz, Germany

  Co-Author: Moritz Brandt – University Medical Center Mainz, Germany

  Co-Author: Stefan Tenzer – University Medical Center Mainz, Germany

  Co-Author: Tommaso Gori – University Medical Center Mainz, Germany

  Co-Author: Hendrik Milting – Herz- und Diabeteszentrum NRW, Bad Oeynhausen

  Co-Author: Wolfram Ruf, MD – University Medicine of the Johannes Gutenberg University Mainz, Center for Thrombosis and Hemostasis (CTH)

  Presenting Author: Philip Wenzel, MD (he/him/his) – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz
• 15:45 – 16:00 ET

  Platelet-derived LTB4 mediates neutrophil recruitment
  

  Presenting Author: Christian Hackenbroch, M.Sc. (he/him/his) – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany

  Co-Author: Carina Gross – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany

  Co-Author: Tugce Cimen – Rudolf Virchow Center for Integrative and Translational Bioimaging University of Würzburg, Würzburg, Germany

  Co-Author: Stefanie Rubenzucker – Department of Analytical Chemistry, University of Vienna, Austria

  Co-Author: Sarah Beck, PhD – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany

  Co-Author: Tamara Girbl – Rudolf Virchow Center for Integrative and Translational Bioimaging University of Würzburg, Würzburg, Germany

  Co-Author: Robert Ahrends, PhD – Department of Analytical Chemistry, University of Vienna, Austria

  Co-Author: David Stegner, PhD (he/him/his) – Institute of Experimental Biomedicine - Chair I, University Hospital and Rudolf Virchow Center for Integrative and Translational Bioimaging, Würzburg, Germany