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    Oral Communication

    Venous Thromboembolism
    Oral Communication Session

    OC 46 - Molecular Insights in Cancer Associated Thrombosis

    Monday, June 26, 2023
    14:45 – 16:00 ET
    Room:510

    Session Available Online As: On-Demand

    Presentations:

    • 14:45 – 15:00 ET
      Absolute quantitative proteomics for occult cancer screening in patient with unprovoked venous thromboembolism: results from the prospective PLATO-VTE study

      Presenting Author: Noori A.M Guman, MD – Dept. of Vascular Medicine, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands

      Co-Author: Noémie Kraaijpoel – Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands

      Co-Author: Frits I. Mulder – Dept. of Vascular Medicine, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands

      Co-Author: Marc Carrier, MD – Ottawa Hospital Research Institute, Ottawa, ON, Canada

      Co-Author: Luis Jara-Palomares – Hospital Universitario Virgen del Rocío, Seville, Spain

      Co-Author: Marcello Di Nisio – Department of Medicine and Ageing Sciences, University G. D'Annunzio, Chieti, Italy

      Co-Author: Walter Ageno, MD (he/him/his) – Department of Medicine and Surgery, University of Insubria, Varese, Italy

      Co-Author: Jan Beyer-Westendorf, MD,PhD – University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Division of Hematology and Hemostasis, Department of Medicine I Thrombosis Research, Dresden, Saxony, Germany

      Co-Author: Erik Klok, MD, PhD, FESC – Leiden University Medical Center

      Co-Author: Thomas Vanassche, MD PhD – University Hospitals Leuven, Belgium

      Co-Author: Hans-Martin M.B. Otten – Dept. of Internal Medicine, Meander Medisch Centrum, Amersfoort, the Netherlands

      Co-Author: Benilde Cosmi – Dept. of Angiology and Blood Coagulation, S. Orsola-Malpighi University Hospital, IRCSS -University of Bologna, Bologna, Italy

      Co-Author: Pieter W. Kamphuisen – Tergooi MC and Amsterdam University Medical Centers

      Co-Author: Verónica Sánchez-López, PhD – Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

      Co-Author: Myron G. Best – Dept. of Neurosurgery, Brain Tumor Center Amsterdam, Cancer Center Amsterdam, Amsterdam UMC/Vrije Universiteit, Amsterdam, the Netherlands

      Co-Author: Patrick M.M. Bossuyt – Dept. of Epidemiology and Data Science, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands

      Co-Author: Henri Versteeg – Leiden University Medical Center

      Co-Author: Bart J.M. van Vlijmen – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.

      Co-Author: Nick van Es, MD PhD (he/him/his) – Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands

      Co-Author: Yassene Mohammed, PhD (he/him/his) – Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands

    • 15:00 – 15:15 ET
      Plasma protein signature by targeted mass spectrometry allows prediction of venous thromboembolism in colorectal cancer patients with 90% sensitivity

      Co-Author: Jeroen Buijs – Leiden University Medical Center

      Co-Author: Nick van Es, MD PhD (he/him/his) – Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands

      Co-Author: Rayna Anijs, MSc – Leiden University Medical Center

      Co-Author: Floris T.M. Bosch – Amsterdam University Medical Centers

      Co-Author: Bart J.M. van Vlijmen – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.

      Co-Author: Frits I. Mulder – Dept. of Vascular Medicine, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands

      Co-Author: Henri Versteeg – Leiden University Medical Center

      Presenting Author: Yassene Mohammed, PhD (he/him/his) – Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands

    • 15:15 – 15:30 ET
      Jak2V617F-positive myeloproliferative neoplasms are associated with impaired fibrinolysis both in mice and humans

      Presenting Author: Marie-Charlotte BOURRIENNE, PharmD (she/her/hers) – Laboratoire d'Hématologie, AP-HP, Hôpital Bichat Claude-Bernard, Paris, France.

      Co-Author: Stéphane Loyau – INSERM UMRS-1148

      Co-Author: Juliette Gay – Laboratoire d'Hématologie, AP-HP, Hôpital Bichat Claude-Bernard, Paris, France.

      Co-Author: Selena Akhenak – INSERM UMRS-1148

      Co-Author: Dorothée FAILLE, PharmD, PhD (she/her/hers) – 1. Université Paris Cité, INSERM, U1148 LVTS, F-75018 Paris. 2. Laboratoire d'Hématologie, AP-HP, Hôpital Bichat Claude-Bernard, F-75018 Paris.

      Co-Author: Christine Dosquet – Unité fonctionnelle de pharmacocinétique, APHP, Hôpital Saint-Louis, Paris France

      Co-Author: Benoit Ho-Tin-Hoe – INSERM UMRS-1148

      Co-Author: Véronique Ollivier, PhD – INSERM UMRS-1148

      Co-Author: Mialitiana Solonomenjanahary – INSERM UMRS-1148

      Co-Author: jean-Luc Villeval – INSERM U1287

      Co-Author: Isabelle Plo – INSERM UMR 1287, Gustave Roussy

      Co-Author: Valérie Edmond – INSERM UMR 1287, Gustave Roussy

      Co-Author: Mikaël MAZIGHI – APHP, Neurology Department, Hôpital Lariboisière, Paris

      Co-Author: Nadine Ajzenberg – Laboratoire d'Hématologie, AP-HP, Hôpital Bichat Claude-Bernard, Paris, France.

    • 15:30 – 15:45 ET
      Association of growth differentiation factor-15 (GDF-15) with thromboembolism and mortality in patients with cancer: findings from the Vienna CATS study

      Presenting Author: Stephan Nopp, MD – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria

      Co-Author: Florian Moik, MD PhD (he/him/his) – Medical University of Vienna, Department of Medicine I, Clinical Division of Haematology and Haemostaseology

      Co-Author: Simon Kraler – Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland

      Co-Author: Cornelia Englisch, MD – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Matthias Preusser – Clinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Arnold von Eckardstein – Institute of Clinical Chemistry, University of Zurich, Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland

      Co-Author: Ingrid Pabinger, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria

      Co-Author: Thomas Lüscher – Center for Molecular Cardiology, University of Zurich, Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland

      Co-Author: Cihan Ay, MD (he/him/his) – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria

    • 15:45 – 16:00 ET
      Tissue Factor Pathway Inhibitor is associated with risk of venous thromboembolism and all-cause mortality in patients with cancer

      Presenting Author: Cornelia Englisch, MD – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Florian Moik, MD PhD (he/him/his) – Medical University of Vienna, Department of Medicine I, Clinical Division of Haematology and Haemostaseology

      Co-Author: Johannes Thaler, MD, PhD (he/him/his) – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Silvia Koder – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Matthias Preusser – Clinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Austria

      Co-Author: Ingrid Pabinger, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria

      Co-Author: Cihan Ay, MD (he/him/his) – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria