Skip to main content
ISTH 2023 Main banner
Back

    Luisa Iruela-Arispe, PhD

    Professor and Chair
    Northwestern University Feinberg School of Medicine
    Chicago, Illinois, United States

    Dr. Luisa Iruela-Arispe is Professor and Chair of Cell and Developmental Biology at Northwestern University. Her research focuses on the signaling pathways that regulate morphogenesis and homeostasis of the vasculature, an effort that has resulted in over 200 peer-reviewed publications. A major component of this work has centered on the multiple effects of VEGF and Notch signaling in blood vessels, including their key contributions to diseases such as Alagille syndrome and CADASIL. In addition, we have expanded current understanding of the mechanisms associated with vascular regeneration and the impact of mechanobiology on vascular function. More recently she identified a cohort of macrophages that bind to the inner surface of the vascular wall and maintain hemostasis under disturbed flow conditions. Her research has received continuous support from the NIH, and specific projects also received support from several foundations including AHA, DOD, and industry.

    Mentoring of trainees and faculty has been a core component of her professional path. In relation to graduate students and post-doctoral fellows, Dr. Iruela-Arispe has embraced the responsibility for the training of a resilient, creative, and diverse cohort of new scientists able to address the most critical questions in biomedicine and to translate findings to clinical care. Since 1994, she mentored 20 graduate students and 23 postdoctoral fellows, all of whom are currently employed in academia, publishing or in industry. In 2009, she was recognized with the Distinguished Teaching Award for excellence in teaching at UCLA and in 2014, she received the post-doctoral mentor award, given to one mentor at UCLA by the post-doctoral society. She has received multiple accolades including the Judah Folkman award for her work on angiogenesis and she was recently selected as a fellow of AAAS.

    Presentation(s):