Internist-hematologist
Radboud university medical center
Nijmegen, Netherlands
Saskia E.M. Schols, PhD and MD, is an internist-hematologist at the Hemophilia Treatment Centre of Nijmegen-Eindhoven-Maastricht, and the department of Hematology of the Radboud university medical centre, Nijmegen, the Netherlands. She combines patient care with performing scientific research, especially in the field of rare bleeding disorders. She is the principal investigator of the nationwide cross-sectional Rare Bleeding disorders in the Netherlands study (RBiN study, inclusion period 2017 - 2019). In this study, patients were included with rare coagulation factor deficiencies and fibrinolytic disorders, both children and adults. She supervises several PhD students aligned to the RBiN study to unravel the Dutch population of rare coagulation factor deficiencies and fibrinolytic disorders by combining data on bleeding severity from questionnaires, with laboratory phenotype (pro- and anticoagulation factor activity levels), thrombin generation profiles and whole exome sequencing analysis with a targeted panel of 156 genes involved in thrombosis and hemostasis. In addition, dr. Schols is also involved in the development of research towards personalized based medicine by performing thrombin generation profiling in hemophilia patients to better predict their bleeding tendency. She is involved in the nationwide Symphony consortium to orchestrate personalized based medicine in the diagnostic work up of patients with a congenital bleeding disorder.
Dr. Schols is board member of the Dutch Society of Hemophilia Physicians and is also involved in the working group for revision of the Dutch Guideline for rare bleeding disorders.
Saturday, June 24, 2023
15:25 – 15:45 ET