Jian-Ke Tie, PhD

Research Associate Professor
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States

Jian-Ke Tie, PhD, is a research associate professor at the University of North Carolina at Chapel Hill. His research interests focus on the structure-function study of enzymes in the vitamin K cycle. This cycle participates in post-translational modification of proteins involved in a broad range of biological functions including blood coagulation, bone homeostasis, signal transduction, and other cell control systems. Through biochemical, molecular and cellular approaches, Dr. Tie seeks to investigate how enzymes in the vitamin K cycle function in their native milieu and how natural mutations in these enzymes lead to distinct genetic disorders.

Presentation(s):

• OC 45.1 - A genome-wide CRISPR-Cas9 knockout screen reveals FSP1 as the warfarin-resistant vitamin K reductase

  Monday, June 26, 2023
  14:45 – 15:00 ET