Prof., Dr.
KU Leuven
Kortrijk, West-Vlaanderen, Belgium
Karen Vanhoorelbeke, PhD, is since 2007 professor at KU Leuven, Campus Kulak, Kortrijk, Belgium, where she is principle investigator at the Laboratory for Thrombosis Research and chairman of the Interdisciplinary Research Facility. In 2010 she worked in the lab of prof. dr. Tim Springer at Harvard Medical School, Boston as a visiting professor.
Her research focuses on the molecular mechanisms by which the hemostatic proteins van Willebrand factor (VWF) and its cleaving enzyme ADAMTS13 contribute to health and disease. Her group performs fundamental research to understand the role of VWF and ADAMTS13 in hemostasis, bleeding and thrombosis and to unravel their mode-of-action. These findings form the basis for translational research lines where preclinical animal models are established to study disease pathology and new treatment strategies.
Her research is embedded in several national and international research projects. She was awarded two Horizon2020 Marie Curie training network grants ‘PROFILE’ and 'TOLERATE' of which she is the coordinator. She is author and coauthor of 200 scientific publications in international peer reviewed journals and is (co) promotor of 32 PhD students.
Saturday, June 24, 2023
13:45 – 14:00 ET
OC 26.6 - Thrombotic Thrombocytopenic Purpura (TTP): Molecular and Clinical
Sunday, June 25, 2023
14:45 – 16:00 ET
Sunday, June 25, 2023
15:00 – 15:15 ET
Sunday, June 25, 2023
15:30 – 15:45 ET
OC 26.5 - Regulation of VWF Cleavage is Mediated by Coupling ADAMTS13 D- and C- Domain Binding Sites
Sunday, June 25, 2023
15:45 – 16:00 ET
PB0873 - Small-molecule cyclophilin inhibitors potently reduce platelet procoagulant activity
Monday, June 26, 2023
18:30 – 19:30 ET
PB1220 - DNase-1 overcomes thrombolytic rt-PA resistance of platelet-rich ischemic stroke thrombi
Tuesday, June 27, 2023
18:30 – 19:30 ET