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    Naoual Ouazzani Chahdi, MSc

    PhD student
    Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands
    Den Haag, Zuid-Holland, Netherlands

    Naoual Ouazzani Chahdi (MSc) is a PhD candidate at Sanquin at the department of Molecular Hematology (Amsterdam, The Netherlands). Naoual has a background in molecular life sciences and is currently in her fourth year of her PhD. Her PhD project focusses on investigating the role of red blood cells in venous thrombosis and finding new therapies for thrombosis. To understand the biological function of red blood cells during thrombus formation, specific red blood cell proteins, membrane proteins as well as intracellular proteins, are being studied. She developed an approach to investigate clot formation and fibrinolysis by using CRISPR-based knockout red blood cells. At this ISTH she will present her work on the role of red blood cell derived transglutaminase 2 on clot formation and red blood cell stability. In addition, she will also show her work focussed on the importance of red blood cells of sickle cell patients in clot stability and how the RBCs contribute to decreased clot lysis.

    Presentation(s):