Skip to main content
ISTH 2023 Main banner
Back
    Oral Communication

    Hemophilia and Rare Bleeding Disorders
    Oral Communication Session

    OC 50 - Hemophilia Clinical - Inhibitors

    Tuesday, June 27, 2023
    10:45 – 12:00 ET
    Room:516

    Session Available Online As: Live-Stream and On-Demand

      Moderator(s)

    • Samantha Gouw, MD, PhD (she/her/hers)

      Pediatric Hematologist
      The University of Amsterdam
      Amsterdam, Noord-Holland, Netherlands

    • Lynn Malec, MD, MSc

      Senior Medical Director
      Versiti Blood Research Institute, Milwaukee, WI, USA; Division of Hematology & Oncology, Departments of Medicine and Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
      Milwaukee, Wisconsin, United States

    Presentations:

    • 10:45 – 11:00 ET
      Levels of IgG4 distinguish immune tolerance induction outcome in patients with inherited hemophilia A: results from the BrazIT Study

      Presenting Author: Daniel G. Chaves, Msc, PhD (he/him/his) – Fundação Centro de Hematologia e Hemoterapia de Minas Gerais (Hemominas), Minas Gerais, Brazil

      Co-Author: Brendon Ayala – Faculdade de Medicina, Universidade Federal de Minas Gerais, Minas Gerais, Brazil

      Co-Author: Ricardo M. Camelo, MD, MSc, MBA – Faculty of Pharmacy, Universidade Federal de Minas Gerais

      Co-Author: Maíse M. Dias – Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil

      Co-Author: Tânia H. Anegawa – Centro Regional de Hematologia e Hemoterapia de Londrina, Paraná, Brazil

      Co-Author: Andrea G. de Oliveira – Fundação Centro de Hematologia e Hemoterapia de Minas Gerais (Hemominas), Minas Gerais, Brazil

      Co-Author: Rosângela A. Ribeiro – Centro de Hematologia e Hemoterapia do Ceará (Hemoce), Ceará, Brazil

      Co-Author: Mônica H. Cerqueira – Instituto de Hematologia do Estado do Rio de Janeiro (Hemorio), Rio de Janeiro, Brazil

      Co-Author: Leina Y. Etto – Centro de Hematologia e Hemoterapia da Paraíba (Hemoíba), Paraíba, Brazil

      Co-Author: Fábia M R A Callado – Fundação de Hematologia e Hemoterapia de Pernambuco (Hemope), Pernambuco, Brazil

      Co-Author: Vivian K B Franco – Centro de Hematologia e Hemoterapia de Santa Catarina (Hemosc), Santa Catarina, Brazil

      Co-Author: Maria do Rosário F. Roberti – Centro de Hematologia e Hemoterapia de Goiás (Hemogo), Goiás, Brazil

      Co-Author: Maria Aline F. Cerqueira – Centro de Hematologia e Hemoterapia do Piauí (Hemopi), Piauí, Brazil

      Co-Author: Ieda S. Pinto – Fundação Centro de Hematologia e Hemoterapia do Pará (Hemopa), Pará, Brazil

      Co-Author: Suely Rezende, MD, PhD (she/her/hers) – Universidade Federal de Minas Gerais

    • 11:00 – 11:15 ET
      Low dose FVIII injections as a potential treatment to prevent Inhibitor development in Hemophilia A - an in vivo study

      Presenting Author: Wajeeha Zaheer (she/her/hers) – McMaster University

      Co-Author: Davide Matino, MD (he/him/his) – Department of Medicine, Division of Hematology, McMaster University, Hamilton, ON

      Co-Author: Anthony KC. Chan, MBBS – McMaster University, McMaster Children’s Hospital, Hamilton, Canada

    • 11:15 – 11:30 ET
      Inhibitor development upon switch after 50 EDs from plasma-derived to recombinant FVIII in PUPs with severe haemophilia A: the PUP-SWITCH study results

      Presenting Author: Syna Miri, MSc – Università degli Studi di Milano, Department of Biomedical Sciences for Health, Milan, Italy

      Co-Author: Frits R. R. Rosendaal – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands

      Co-Author: Kaan Kavakli – Ege Hemophilia Center, Izmir, Turkey

      Co-Author: Peyman Eshghi, MD – Pediatric Congenital Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

      Co-Author: Soha Mohammadi Moghaddam – Pediatric Congenital Hematologic Disorders Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

      Co-Author: Mohsen Elalfy – Ain Shams University, Cairo, Egypt

      Co-Author: Susan Halimeh – Gerinnungszentrum Rhein-Ruhr

      Co-Author: Dilek Gürlek Gökçebay – Ministry of Health Ankara City Hospital, Ankara, Turkey

      Co-Author: Namık Özbek – Ministry of Health Ankara City Hospital, Ankara, Turkey

      Co-Author: Tiraje Celkan – Cerrahpaşa Faculty of Medicine, İstanbul University, Istanbul, Turkey

      Co-Author: Ahmad Mohammadi – Seyed Shohada Hospital, Esfahan Hemophilia Treatment Centre, Esfahan, Iran

      Co-Author: Mehran Karimi, MD – Shiraz University of Medical Sciences, Shiraz, Iran

      Co-Author: Bariş Yılmaz – Marmara University, Istanbul, Turkey

      Co-Author: Canan Albayrak, MD (she/her/hers) – Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey

      Co-Author: Burçak Tatli Güneş – Tepecik Education and Research Hospital, Izmir, Turkey

      Co-Author: Zühre Kaya, MD – Gazi University Faculty of Medicine, Department of Pediatric Hematology

      Co-Author: Yilmaz Ay – Pamukkale University Faculty of Medicine, Denizli, Turkey

      Co-Author: Sinan Akbayram – Gaziantep University Faculty of Medicine, Gaziantep, Turkey

      Co-Author: Hale Ören, MD (she/her/hers) – Dokuz Eylül University Faculty of Medicine

      Co-Author: Flora Peyvandi, MD, PhD (she/her/hers) – IRCCS Ca' Granda Maggiore Hospital Foundation, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

    • 11:30 – 11:45 ET
      Maternal microchimerism promote FVIII tolerance in haemophilia A children with inhibitor under ITI

      Co-Author: Zekun Li, PhD – Hemophilia Comprehensive Care Center, Hematology Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health

      Co-Author: Yeling lu – Faculty of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

      Presenting Author: Zhenping CHEN, MD – Beijing Children’s Hospital, Capital Medical University

      Co-Author: Jing Dai – Shanghai Jiaotong University School of Medicine affiliated Ruijin Hospital

      Co-Author: Wenman Wu – Department of Clinical Laboratory Medicine

      Co-Author: Xuefeng Wang – Faculty of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine

      Co-Author: Runhui Wu – Beijing Children’s Hospital, Capital Medical University, Beijing, China

    • 11:45 – 12:00 ET
      Prediction of inhibitor development in previously untreated children with hemophilia A using a machine-learning network and information theory quantifiers: Results from the HEMFIL Cohort Study

      Presenting Author: Letícia Lemos Jardim, PhD (she/her/hers) – Instituto René Rachou (Fiocruz Minas), Belo Horizonte, Minas Gerais, Brazil

      Co-Author: Tiago A. Schieber – Faculdade de Ciências Econômicas

      Co-Author: Marcio Portugal Santana – Fundação Hemominas

      Co-Author: Vivian K B Franco – Centro de Hematologia e Hemoterapia de Santa Catarina (Hemosc), Santa Catarina, Brazil

      Co-Author: Mônica H. Cerqueira – Instituto de Hematologia do Estado do Rio de Janeiro (Hemorio), Rio de Janeiro, Brazil

      Co-Author: Claudia Santos Lorenzato – Centro de Hematologia e Hemoterapia do Paraná (HEMEPAR),

      Co-Author: Luciana Werneck Zuccherato, PhD – Faculty of Medicine, Universidade Federal de Minas Gerais

      Co-Author: Daniel Gonçalves Chaves – Fundação Hemominas

      Co-Author: Suely Rezende, MD, PhD (she/her/hers) – Universidade Federal de Minas Gerais