OC 18 - Modulators of Platelet Function

Moderator(s)

• 

  Marie Hollenhorst, MD PhD (she/her/hers)

  Instructor, Associate Physician
  Brigham and Women's Hospital, Harvard Medical School
  Boston, Massachusetts, United States
• 

  Marie Lordkipanidzé, B.Pharm, PhD (she/her/hers)

  Associate professor
  Research Center
  Faculty of pharmacy, University of Montreal
  Montreal, Quebec, Canada

Presentations:

• 10:45 – 11:00 ET

  The role of Mitochondrial Calcium Uniporter in platelet function
  

  Presenting Author: Abigail Ajanel, MS (she/her/hers) – University of Utah

  Co-Author: Frederik Denorme, PhD (he/him/his) – University of Utah

  Co-Author: Irina Portier, PhD – University of Utah

  Co-Author: Yasuhiro Kosaka – University of Utah Molecular Medicine Program

  Co-Author: Robert A. Campbell, PhD – University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
• 11:00 – 11:15 ET

  A signature of platelet reactivity in complete blood count scattergrams identifies genes with thrombotic disease associations
  

  Co-Author: Hippolyte Verdier – Institut Pasteur, CNRS

  Co-Author: Kate Downes, PhD – East Genomics, Cambridge Genomics Laboratory

  Co-Author: William Astle – University of Cambridge

  Presenting Author: Ernest Turro, PhD – Icahn School of Medicine at Mount Sinai
• 11:15 – 11:30 ET

  Platelet mitochondrial bioenergetics is critical for clot contraction, hemostasis and thrombosis
  

  Presenting Author: Kanakanagavalli Shravani Prakhya, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA

  Co-Author: Hemendra Vekaria – University of Kentucky

  Co-Author: Joshua Lykins – University of Kentucky

  Co-Author: Daniëlle M. Coenen, MSc, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA

  Co-Author: Smita Joshi, PhD (she/her/hers) – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA

  Co-Author: Patrick Sullivan – University of Kentucky

  Co-Author: Sidney W. Whiteheart – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
• 11:30 – 11:45 ET

  Actin Bundling Protein L-Plastin Regulates Platelet Spreading and Thrombosis
  

  Co-Author: Li GUO, MD PhD (she/her/hers) – 1. Bloodworks Research Institute; 2. Hematology Division University of Washington; 3. University of Utah

  Presenting Author: Raymond Adili – Bloodworks Research Institute

  Co-Author: Shancy Jacob – Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA

  Co-Author: Bhanu Kanth Manne – University of Utah

  Co-Author: Seema Bhatlekar – University of Utah
• 11:45 – 12:00 ET

  Alpha-dystroglycan supports platelet aggregation and hemostasis/thrombosis via binding to GPIbα
  

  Presenting Author: Viktor Prifti – Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

  Co-Author: Reid Gallant – Department of Medicine, University of Toronto, Toronto, Canada

  Co-Author: Aron A. Shoara, PhD – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada

  Co-Author: Kanwal Singh – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada

  Co-Author: Xi Lei – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada

  Co-Author: Yiming Wang – Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada

  Co-Author: Heyu Ni, MD, PhD – Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada