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    Brooke Sadler, PhD, MA

    Assistant Professor in Pediatrics, Hematology and Oncology
    Department of Pediatrics, School of Medicine, Washington University
    St. Louis, Missouri, United States

    Dr. Brooke Sadler, PhD, is an Assistant Professor in the Department of Pediatrics, Division of Hematology and Oncology at Washintgon University School of Medicine in St. Louis. She is an ASH Scholar Award recipient and the co-director of a genetics and genomics core for a program project grant on the biology of von Willebrand Disease, but has also done work on the genetics of heavy menstrual bleeding, COVID-19, and several pediatric musculoskeletal and neurological disorders. She is engaged in performing bioinformatical analyses on large-scale genomic datasets. She is currently using her interdisciplinary skills from genetics, evolutionary biology and epidemiology to attempt to explain the missing genetic heritability in Type 1 von Willebrand Disease (VWD), as well as determine the effect of rare variants including rare CNVs and structural variation on genetic risk for VWF and other pediatric disorders of bleeding and clotting. She and her collaborators are in the process of moving towards a multi-omic approach to these disorders, as this is where the field is currently headed.

    Presentation(s):