Assistant Professor
University of Lodz, Faculty of Biology and Environmental Protection, Department of General Biochemistry
Lodz, Lodzkie, Poland
PhD DSc Michał Błażej Ponczek is a biochemist and bioinformatician in the field of hemostasis and a research and teaching employee at the Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Poland.
He graduated from biological studies in the specialty of biochemistry in 2003 (MSc), completed postgraduate studies in computer science in 2007, obtained a doctorate in the field of biological sciences in the discipline of biochemistry in the specialty of blood coagulation biochemistry (PhD) in 2007 (Modifications of fibrinogen coagulation activity Induced by reactive nitrogen and oxygen Species) and habilitation (DSc) in 2017 (Application of bioinformatic and computational chemistry in the study of evolution and biochemical processes of serine proteases of blood coagulation and fibrinolysis) in the discipline of biochemistry, specialization in bioinformatics. He completed internships abroad as a Postdoctoral Fellow as part of the 2008 EMBO Short-Term Fellowship (ASTF 83.00-2008) at the University of California (Russell Doolittle lab), and as a Visiting Scholar in 2019 at the Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, USA (David Gailani lab).
Scientific interests and methods include molecular evolution, phylogenetics, molecular modeling, docking, dynamics, and bioinformatics in the field of biochemistry of proteins of hemostasis and drug design, with particular emphasis on the importance of contact proteases (FXI, FXII, PK) in thrombotic diseases, simulations of ligand binding to proteins - molecular docking, structural prediction, modeling, molecular dynamics and other analyses of proteins, drug likeliness prediction, and structural biology - CryoEM - the structure of kininogens.
Monday, June 26, 2023
18:30 – 19:30 ET
Wednesday, June 28, 2023
10:30 – 10:45 ET