PhD student
Inserm, Univ Brest, CHRU Brest, UMR 1304, GETBO, Brest, France
BREST, Bretagne, France
My name is Marion PILARD, I am a PhD student at the Brittany research group on thrombosis (GETBO - INSERM 1304) in Brest, France. I am studying the epigenetic mechanisms involved in endothelial dysfunction in thromboembolic venous disease and how it may be implicated in the recurrence of venous thrombosis. I work with two distinct models: an in vitro model in which I use human umbilical vein endothelial cells (HUVEC) and an in vivo model in which I mimic a venous thrombosis event via the induction of an electric current in the inferior vena cava in mice. During my thesis I wrote a review on the importance of endothelial cell phenotype in venous thromboinflammation.
Previously, I obtained my Master degree in Gene Cell Development at the University of Paris-Saclay. I did an internship in which I published a scientific paper on the role of glucose on Sup35p prion export via vesicular traffic.
During my thesis, I also teach classes at the University of Bretagne Occidentale (UBO).
Pilard M, Ollivier EL, Gourdou-Latyszenok V, Couturaud F, Lemarié CA. Endothelial Cell Phenotype, a Major Determinant of Venous Thrombo-Inflammation. Front Cardiovasc Med. 2022 Apr 21;9:864735.
Kabani M, Pilard M, Melki R. Glucose availability dictates the export of the soluble and prion forms of Sup35p via periplasmic or extracellular vesicles. Mol Microbiol. 2020 Aug;114(2):322-332.
OC 19.2 - HDAC6 regulates endothelial dysfunction in thromboembolic venous disease
Sunday, June 25, 2023
11:00 – 11:15 ET