Research TechnicianThomas Jefferson UniversityPhiladelphia, Pennsylvania, United States
OC 23.3 - Naked miRNA mimics and siRNAs selectively transfect megakaryocytes and platelets in vivo and durably suppress target gene expression to modulate megakaryocyte and platelet function in mice.
Sunday, June 25, 202315:15 – 15:30 ET
PB0394 - Argonaute2 (Ago2) modulates megakaryocyte development and platelet reactivity in a sex-specific manner via suppression of mitochondrial genes; evidence for diverse RNA granule species in platelets.
Sunday, June 25, 202318:30 – 19:30 ET
OC 61.5 - Plasma growth factors drive constitutive translation in circulating platelets to maintain protein homeostasis and regulate platelet GPCR reactivity and the hemostatic and thrombotic balance.
Tuesday, June 27, 202315:45 – 16:00 ET
