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    Oral Communication

    Vascular Biology
    Oral Communication Session

    OC 10 - Mechanisms Regulating Vessel Wall Function and Integrity

    Saturday, June 24, 2023
    13:00 – 14:15 ET
    Room:515

    Session Available Online As: On-Demand

    Presentations:

    • 13:00 – 13:15 ET
      The impact of the platelet collagen receptor GPVI on inflammation and extracellular matrix remodelling in abdominal aortic aneurysm formation

      Presenting Author: Tobias Feige, M.Sc. (he/him/his) – Department of Vascular and Endovascular Surgery, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

      Co-Author: Agnes Ehrenberg, M.Sc. (she/her/hers) – Department of Vascular and Endovascular Surgery

      Co-Author: Kim-Jürgen Krott – Clinic of Vascular and Endovascular Surgery,University Clinic of the Heinrich-Heine-University, Düsseldorf, Germany

      Co-Author: Madhumita Chatterjee – Department of Pharmacology, Experimental Therapy and Toxicology, University Hospital Tübingen, Tübingen, Germany

      Co-Author: Mulorz Joscha – Clinic of endovascular surgery

      Co-Author: Hubert Schelzig – Clinic of endovascular surgery

      Co-Author: Margitta Elvers – Clinic for Vascular- and Endovascular Surgery, University Clinic of the Heinrich-Heine- University Düsseldorf, Düsseldorf, Germany.

    • 13:15 – 13:30 ET
      Mechanical stress induces an anti-fibrinolytic and pro-thrombotic state in macrophages and smooth muscle cells in atherosclerotic lesions

      Presenting Author: Frieda Marka, MSc (she/her/hers) – Medical university of vienna

      Co-Author: Roman Lieber – Medical University of Vienna

      Co-Author: Laura Boccuni – Medical University of Vienna

      Co-Author: Manuel Salzmann, PhD (he/him/his) – Medical University of Vienna

      Co-Author: Barbara Kapeller – Medical University of Vienna

      Co-Author: Max Lenz – Medical University of Vienna

      Co-Author: Mira Brekalo – Medical University of Vienna

      Co-Author: Julia B. Pointner, PhD – Medical University of Vienna

      Co-Author: Bruno Podesser – Medical University of Vienna

      Co-Author: Philipp Hohensinner – Medical University of Vienna

    • 13:30 – 13:45 ET
      Platelets mediate intracranial aneurysm formation and rupture in mice

      Presenting Author: Clémence MAUPU – INSERM

      Co-Author: Héloïse Lebas, PhD – INSERM U1148, Université Paris Cité

      Co-Author: Jonas SALFATI – INSERM

      Co-Author: Alexandre Boutigny – INSERM

      Co-Author: Caterina Casari, PhD (she/her/hers) – Laboratory for Hemostasis, Inflammation and Thrombosis, Unité Mixte de Recherche S1176, Institut National de la Santé et de la Recherche Médicale, Université Paris-Saclay

      Co-Author: Craig Fletcher – Department of Pathology and Laboratory Medicine

      Co-Author: jerry Ware – Physiology and Biophysics, University of Arkansas for Medical Sciences

      Co-Author: Pamela Conley – Portola Pharmaceuticals, Inc.

      Co-Author: Pierre Mangin – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France

      Co-Author: Bernhard Nieswandt – Institute of Experimental Biomedicine - Chair I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Biomaging, University of Würzburg, Germany

      Co-Author: Stéphane Loyau – INSERM UMRS-1148

      Co-Author: Philippe Bonnin – Service de physiopathologie clinique exploration fonctionnelles, AP-HP, hôpital Lariboisière

      Co-Author: Véronique AROCAS – Inserm U1148

      Co-Author: Martine JANDROT-PERRUS, MD., PhD. (she/her/hers) – INSERM

      Co-Author: Marie-Christine BOUTON – Inserm U1148

      Co-Author: Yacine Boulaftali, PhD – Unité INSERM U1148, Université Paris Cité

    • 13:45 – 14:00 ET
      Proprotein convertase subtilisin kexin type 9 inhibitors reduce platelet nets release driver thrombosis in familial hypercholesterolemia

      Presenting Author: Vittoria Cammisotto, PhD – Sapienza University of Rome,Department of Clinical Internal, Anaesthesiological and Cardiovascular Sciences

      Co-Author: Francesco Baratta – Sapienza University of Rome,Department of Clinical Internal, Anaesthesiological and Cardiovascular Sciences

      Co-Author: Cristina Nocella, PhD – Sapienza University of Rome, Department of Clinical Internal, Anesthesiology and Cardiovascular Sciences

      Co-Author: Simona Bartimoccia – Sapienza University of Rome,Department of Clinical Internal, Anaesthesiological and Cardiovascular Sciences

      Co-Author: Valentina Castellani – Sapienza University of Rome, Department of General Surgery and Surgical Speciality Paride Stefanini

      Co-Author: Laura D’Erasmo – 4Department of Translationaland Precision Medicine, Sapienza Universityof Rome, Rome, Italy

      Co-Author: Cristina Barale – Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

      Co-Author: Roberto Scicali – Department of Clinicaland ExperimentalMedicine, InternalMedicine, Universityof Catania, Catania, Italy

      Co-Author: Isabella Russo – Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

      Co-Author: Francesco Purrello – Department of Clinical and Experimental Medicine, Internal Medicine, University of Catania, Catania,

      Co-Author: Marcello Arca – Department of Translationaland Precision Medicine, Sapienza Universityof Rome, Rome, Italy

      Co-Author: Daniele Pastori – Department of Clinical, InternalMedicine, Anesthesiologicaland CardiovascularSciences, Sapienza Universityof Rome, Rome, Italy

      Co-Author: Roberto Carnevale – Sapienza University of Rome, Department of Medical-Surgical Sciences and Biotechnologies

      Co-Author: Francesco Violi, Professor of internal medicine, Sapienza University, Rome – Department of Clinical, InternalMedicine, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy

      Co-Author: Pasquale Pignatelli, PhD – Dept. of Clinical, Internistic, Anesthesiologic and Cardiovascular Sciences, Sapienza University

    • 14:00 – 14:15 ET
      Endotheliopathy, innate-immune activation and hemostatic imbalance underlying CAR -T cell toxicities: tools for early and differential diagnosis

      Co-Author: Ana Belén Moreno-Castaño, MD – Hemostasis and Erythropathology Laboratory, Hematopathology, Department of Pathology, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

      Co-Author: Sara Fernandez – Medical Intensive Care Unit, Hospital Clinic, Barcelona, Spain.

      Co-Author: Marta Palomo – Hematology External Quality Assessment Laboratory, Biomedical Diagnostic Center, Hospital Clinic of Barcelona, Barcelona, Spain.

      Presenting Author: Julia Martinez-Sanchez, PhD – Hemostasis and Erythropathology Laboratory, Hematopathology, Department of Pathology, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.

      Co-Author: Alex Ramos – Josep Carreras Leukaemia Research Institute (Campus Clinic). Barcelona

      Co-Author: Patricia Molina – Hemostasis and Erythropathology Laboratory, Hematopathology, Pathology Department, Centre Diagnòstic Biomèdic (CDB), Hospital Clínic, Barcelona, Spain

      Co-Author: Marc Pino – Hemostasis and Erythropatology Laboratory, Pathology Department, CDB

      Co-Author: Valentín Ortiz-Maldonado – Hematology Department, Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Barcelona

      Co-Author: Julio Delgado – Hematology Department, Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Barcelona

      Co-Author: Carlos Fernández de Larrea – Hematology Department, Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Barcelona

      Co-Author: Álvaro Urbano – Hematology Department, Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Barcelona

      Co-Author: Gines Escolar – Hemostasis and Erythropathology Laboratory, Hematopathology, Department of Pathology, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

      Co-Author: Enric Carreras – Josep Carreras Leukaemia Research Institute, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.

      Co-Author: Francesc Fernández-Avilés – Hematology Department, Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Barcelona

      Co-Author: Pedro Castro – Medical Intensive Care Unit, Hospital Clinic, Barcelona, Spain.

      Co-Author: Maribel Diaz-Ricart – Hemostasis and Erythropathology Laboratory, Hematopathology, Department of Pathology, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.