OC 62 - Novel Antithrombotic Strategies

Moderator(s)

• 

  Georges JOURDI, PharmD, PhD (he/him/his)

  Associate Professor in Hematology
  Université Paris Cité and APHP. Nord
  Paris, Ile-de-France, France
• 

  Deborah Siegal, MD MSc FRCPC

  Associate Professor/Associate Scientist
  Medicine and Clinical Epidemiology Program
  The Ottawa Hospital
  Ottawa, Ontario, Canada

Presentations:

• 14:45 – 15:00 ET

  Differential suppression of arterial versus venous thrombosis but preserved hemostasis in mice expressing fibrinogen that cannot support fibrin formation
  

  Presenting Author: Woosuk Steve Hur, PhD – University of North Carolina at Chapel Hill

  Co-Author: Tomohiro Kawano – University of North Carolina at Chapel Hill

  Co-Author: Jean Marie Mwiza, PhD (he/him/his) – University of North Carolina at Chapel Hill

  Co-Author: David S. Paul, PhD – University of North Carolina at Chapel Hill

  Co-Author: Robert H. H. Lee, PhD – University of North Carolina at Chapel Hill

  Co-Author: Emily G. Clarke – University of North Carolina at Chapel Hill

  Co-Author: Emma Bouck – University of North Carolina at Chapel Hill

  Co-Author: Nigel Mackman, PhD – Univerisity of North Carolina at Chapel Hill

  Co-Author: Alisa S. Wolberg, PhD – Univerisity of North Carolina at Chapel Hill

  Co-Author: Wolfgang Bergmeier, PhD – University of North Carolina at Chapel Hill

  Co-Author: Matthew J. Flick, PhD – University of North Carolina at Chapel Hill
• 15:00 – 15:15 ET

  Antiplatelet and anticoagulant compound (APAC) restricts thromboinflammation to ameliorates myocardial ischemia reperfusion injury
  

  Co-Author: Sameen Fatima, MPhil – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany

  Co-Author: Saira Ambreen – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany

  Co-Author: Shrey Kohli, PhD – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany

  Co-Author: Riitta Lassila, MD, PhD (she/her/hers) – Helsinki University Hospital, Coagulation Disorders Unit, Department of Haematology, Comprehensive Cancer Centre, and Research Program Unit in System Oncology, University of Helsinki, Helsinki, Finland

  Co-Author: Berend Isermann, PhD MD (he/him/his) – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany

  Presenting Author: Khurrum Shahzad – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University hospital Leipzig, Leipzig, Germany
• 15:15 – 15:30 ET

  A noble metal stent coating reduces thrombo-inflammatory reactions and acute stent thrombosis – an in vitro and in vivo study
  

  Presenting Author: Mikael Sandell, MSc (he/him/his) – KTH Royal Institute of Technology

  Co-Author: Anna Ericsson – Bactiguard AB

  Co-Author: Jonathan Al-Saadi – Karolinska Institute

  Co-Author: Billy Södervall – Bactiguard AB

  Co-Author: Erika Södergren – Bactiguard AB

  Co-Author: Stefan Grass – Bactiguard AB

  Co-Author: Javier Sanchez – Bactiguard AB

  Co-Author: Staffan Holmin – Karolinska Institute
• 15:30 – 15:45 ET

  Factor XI(a) antibody abelacimab reduces thrombus growth and propagation in a baboon model of vascular graft thrombosis.
  

  Presenting Author: Michael Wallisch, PhD (he/him/his) – Aronora, Inc.

  Co-Author: Yasser Khder – Anthos Therapeutics, Inc.

  Co-Author: Jennifer Johnson – Oregon Health & Science University

  Co-Author: Monica T. Hinds – Oregon Health & Science University

  Co-Author: Erik I. Tucker – Aronora, Inc.

  Co-Author: Dan Bloomfield, MD (he/him/his) – Anthos Therapeutics, Inc.

  Co-Author: Andras Gruber – Aronora, Inc.
• 15:45 – 16:00 ET

  Next-generation, dendrimer-like polyphosphate inhibitor is a safe and effective antithrombotic agent
  

  Presenting Author: Stephanie A. Smith, DVM (she/her/hers) – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA

  Co-Author: Chanel La – Centre for Blood Research, University of British Columbia

  Co-Author: Sreeparna Vappala, PhD (she/her/hers) – University of British Columbia

  Co-Author: Raymond Adili – Bloodworks Research Institute

  Co-Author: Catherine Luke – University of Michigan

  Co-Author: Srinivas Abbina – Centre for Blood Research, University of British Columbia

  Co-Author: Haiming D. Luo – Centre for Blood Research, University of British Columbia

  Co-Author: Irina Chafeeva – Centre for Blood Research, University of British Columbia

  Co-Author: Matthew Drayton – Centre for Blood Research, University of British Columbia

  Co-Author: Louise A. Creagh – University of British Columbia

  Co-Author: Nicole Rhoads – Bloodworks Research Institute

  Co-Author: Manu Thomas Kalathottukaren – University of British Columbia

  Co-Author: Peter Henke – University of Michigan

  Co-Author: Suzana K. Straus – University of British Columbia

  Co-Author: Caigan Du – University of British Columbia

  Co-Author: Edward M Conway, MD, PhD – Centre for Blood Research, University of British Columbia

  Co-Author: Michael Holinstat, PhD – University of Michigan

  Co-Author: Charles A Haynes – Michael Smith Laboratories, Chemical & Biological Engineering, University of British Columbia

  Co-Author: James H. Morrissey, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA

  Co-Author: Jayachandran N. Kizhakkedathu, PhD (he/him/his) – Centre for Blood Research, University of British Columbia