OC 65 - Inherited and Acquired Platelet Disorders

Moderator(s)

• PP

  Patricia Pelletier, MD

  Hematologist and Director of Transfusion Medicine Service
  McGill University Health Centre, Montreal, QC, Canada
• 

  Kathleen Freson, PhD

  Professor
  Cardiovascular Sciences
  Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium.
  Leuven, Vlaams-Brabant, Belgium

Presentations:

• 14:45 – 15:00 ET

  Long-Term Efficacy and Safety With Oral Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients With Immune Thrombocytopenia
  

  Presenting Author: David J. J. Kuter, MD, DPhil – Hematology Division, Massachusetts General Hospital, Harvard Medical School

  Co-Author: Merlin Efraim – Multiprofile Hospital for Active Treatment Sveta Marina EAD

  Co-Author: Zane Kaplan – Monash Medical Centre

  Co-Author: Jiri Mayer – Department of Internal Medicine, Hematology and Oncology, Masaryk University Hospital

  Co-Author: Philip Choi, MBBS PhD FRACP FRCPA – Canberra Hospital

  Co-Author: Gerard A. J. Jansen – Department of Hematology, Erasmus MC, University Medical Center

  Co-Author: Vickie McDonald – Barts Health NHS Trust, The Royal London Hospital

  Co-Author: Ross Baker, MD – Health Futures Institute, Murdoch University, Perth, Australia

  Co-Author: Robert Bird – Princess Alexandra Hospital

  Co-Author: Mamta Garg – Leicester Royal Infirmary

  Co-Author: Jaromír Gumulec – Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine University of Ostrava

  Co-Author: Milan Košťál – University Hospital of Hradec Králové

  Co-Author: Terry Gernsheimer – University of Washington Medical Center

  Co-Author: Waleed Ghanima, MD – Østfold Hospital Foundation

  Co-Author: Umer Khan – Sanofi, San Diego, CA, USA

  Co-Author: Ahmed Daak – Sanofi Genzyme

  Co-Author: Nichola Cooper, MS (Cantab), MBBS, MD, FRCP, FRCPath, – Hammersmith Hospital
• 15:15 – 15:30 ET

  LongRead Nanopore Sequencing reveal novel structural variants in ITGB3, HPS5 and HPS3, allowing genetic diagnosis of Glanzmann's Thrombasthenia and Hermansky-Pudlak Syndrome in four unrelated patients
  

  Presenting Author: Ana Marin-Quilez, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, University of Murcia, IMIB, CIBERER-U765, Murcia, Spain

  Co-Author: Ana Zamora-Cánovas – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain.

  Co-Author: Belen de la morena-Barrio, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain

  Co-Author: Cristina Sierra Aisa, MD – Hospital Universitario Cruces (Barakalo-Bizkaia)

  Co-Author: Christoph Male, MD, MSc – Department of Paediatrics, Medical University of Vienna, Vienna, Austria.

  Co-Author: Jose Padilla – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain

  Co-Author: Nuria Fernández-Mosteirín, PhD MD – Hospital Universitario Miguel Servet (Zaragoza)

  Co-Author: María Trapero-Marugán – Hospital Universitario Puerta de Hierro, Madrid

  Co-Author: Pedro L Gómez-González – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain.

  Co-Author: Maria Eugenia de la Morena-Barrio, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Arrixaca, CIBERER, Murcia, Spain

  Co-Author: Ana Sánchez-Fuentes, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER-U765, Murcia

  Co-Author: Agustín Rodríguez-Alén – Hematology Department, Hospital Universitario de Toledo, Spain

  Co-Author: Nuria Revilla, MD, PhD – Hospital Universitario Fundación Jiménez Díaz, Instituto Investigación Sanitaria FJD (IIS-FJD) Madrid, Spain.

  Co-Author: Rocío Benito – Cancer Research Center - CSIC, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Spain

  Co-Author: Jose Mª Bastida, PhD, MD – Complejo Asistencial Universitario de Salamanca-IBSAL-USAL (Salamanca)

  Co-Author: María Luisa Lozano – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain

  Co-Author: Javier Corral, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, CIBERER, Murcia, Spain

  Co-Author: José RIVERA Rivera, PhD – Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, Murcia, Spain
• 15:45 – 16:00 ET

  Platelet-specific gene dysregulation and intron retention in a patient with syndromic thrombocytopenia
  

  Presenting Author: Fabienne Ver Donck, MS – KU Leuven

  Co-Author: Koen De Wispelaere – KU Leuven

  Co-Author: Kato Ramaekers – KU Leuven

  Co-Author: Chantal Thys – KU Leuven

  Co-Author: Veerle Labarque, MD, PhD – University Hospitals Leuven, Belgium

  Co-Author: Ernest Turro, PhD – Icahn School of Medicine at Mount Sinai

  Co-Author: Kathleen Freson, PhD – Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium.